Hypoxia triggers a HIF-mediated differentiation of peripheral blood mononuclear cells into osteoclasts

Orthodontics and Craniofacial Research

Volumn 15, Issue 1, 2012, Pages 1-9

  Dandajena, T C ^a,b   Ihnat, M A ^b   Disch, B ^a   Thorpe, J ^b   Currier, G F ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Hypoxia; Monocyte; Osteoclast; RANKL; Vascular endothelial growth factor

Indexed keywords

3-(5'-HYDROXYMETHYL-2'-FURYL)-1-BENZYLINDAZOLE; ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BIOLOGICAL MARKER; CARBOXYFLUORESCEINDIACETATE; DIAGNOSTIC AGENT; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDAZOLE DERIVATIVE; ISOENZYME; LIFICIGUAT; OSTEOCLAST DIFFERENTIATION FACTOR; TARTRATE-RESISTANT ACID PHOSPHATASE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; BONE REMODELING; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE; CULTURE TECHNIQUE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MONONUCLEAR CELL; OSTEOBLAST; OSTEOCLAST; PHYSIOLOGY; UPREGULATION; WESTERN BLOTTING;

ACID PHOSPHATASE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BONE REMODELING; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCEINS; FLUORESCENT DYES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INDAZOLES; ISOENZYMES; LEUKOCYTES, MONONUCLEAR; OSTEOBLASTS; OSTEOCLASTS; RANK LIGAND; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84856206023     PISSN: 16016335     EISSN: 16016343     Source Type: Journal    
DOI: 10.1111/j.1601-6343.2011.01530.x     Document Type: Article

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