Hyperglycaemia emerging during general anaesthesia induces rat acute kidney injury via impaired microcirculation, augmented apoptosis and inhibited cell proliferation

Nephrology

Volumn 17, Issue 2, 2012, Pages 111-122

  Efrati, Shai ^a,b   Berman, Sylvia ^a,b   Hamad, Ramzia Abu ^b   Siman Tov, Yariv ^b   Chanimov, Michael ^b   Weissgarten, Joshua ^a  

^a Nephrology Division   (Israel)

^b ASSAF HAROFEH MEDICAL CENTER   (Israel)

Author keywords

acute kidney injury; anaesthesia; hyperglycaemia; renal auto regulation

Indexed keywords

ANESTHETIC AGENT; ANGIOTENSIN II; CYSTATIN C; GLUCOSE; INSULIN; UREA;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD PRESSURE; CELL PROLIFERATION; CONTROLLED STUDY; GENERAL ANESTHESIA; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN SYNTHESIS; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY PERFUSION; KIDNEY TUBULE; LASER DOPPLER FLOWMETRY; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

ACUTE KIDNEY INJURY; ANESTHESIA, GENERAL; ANGIOTENSIN II; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; CELL PROLIFERATION; CYSTATIN C; DISEASE MODELS, ANIMAL; GLUCOSE; HYPERGLYCEMIA; INSULIN; KIDNEY; MICROCIRCULATION; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; TIME FACTORS; UREA;

EID: 84856205851     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2011.01538.x     Document Type: Article

References (40)

1. Tallgren M, Niemi T, Poyhia R, et al,. Acute renal injury and dysfunction following elective abdominal aortic surgery. Eur. J. Vasc. Endovasc. Surg. 2007; 33: 550-5. (Pubitemid 46547476)
2. Wagener G, Brentjens TE,. Renal disease: The anesthesiologist's perspective. Anesthesiol. Clin. 2006; 24: 523-47. (Pubitemid 44416157)
3. Coleman MD, Shaefi S, Sladen RN,. Preventing acute kidney injury after cardiac surgery. Curr. Opin. Anaesthesiol. 2011; 24: 70-6.
4. Brienza N, Giglio MT, Marucci M,. Preventing acute kidney injury after noncardiac surgery. Curr. Opin. Crit. Care 2010; 16: 353-8.
5. Pisimisis GT, Khoynezhad A, Bashir K, Kruse MJ, Donayre CE, White RA,. Incidence and risk factors of renal dysfunction after thoracic endovascular aortic repair. J. Thorac. Cardiovasc. Surg. 2010; 140: S161-167.
6. Rosner MH, Portilla D, Okusa MD,. Cardiac surgery as a cause of acute kidney injury: Pathogenesis and potential therapies. J. Intensive Care Med. 2008; 23: 3-18.
7. Rosner MH, Okusa MD,. Acute kidney injury associated with cardiac surgery. Clin. J. Am. Soc. Nephrol. 2006; 1: 19-32.
8. Jimi N, Segawa K, Minami K, Sata T, Shigematsu A,. Inhibitory effect of the intravenous anesthetic, ketamine, on rat mesangial cell proliferation. Anesth. Analg. 1997; 84: 190-5. (Pubitemid 27020982)
9. Stockand JD, Sansom SC,. Regulation of filtration rate by glomerular mesangial cells in health and diabetic renal disease. Am. J. Kidney Dis. 1997; 29: 971-81. (Pubitemid 27251854)
10. Stockand JD, Sansom SC,. Glomerular mesangial cells: Electrophysiology and regulation of contraction. Physiol. Rev. 1998; 78: 723-44. (Pubitemid 28340601)
11. Vol A, Gribova O, Berman S, Siman-Tov Y, Efrati S,. Application of muscle biopotential measurement for sustained, noninvasive blood glucose survey. J. Appl. Physiol. 2009; 107: 253-60.
12. Efrati S, Berman S, Siman-Tov Y, et al,. N-acetylcysteine attenuates NSAID-induced rat renal failure by restoring intrarenal prostaglandin synthesis. Nephrol. Dial. Transplant. 2007; 22: 1873-81. (Pubitemid 47244755)
13. Herget-Rosenthal S, Marggraf G, Husing J, et al,. Early detection of acute renal failure by serum cystatin C. Kidney Int. 2004; 66: 1115-22. (Pubitemid 39121017)
14. Madero M, Sarnak MJ, Stevens LA,. Serum cystatin C as a marker of glomerular filtration rate. Curr. Opin. Nephrol. Hypertens. 2006; 15: 610-6. (Pubitemid 44607433)
15. Just A,. Mechanisms of renal blood flow autoregulation: Dynamics and contributions. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007; 292: R1-17. (Pubitemid 46089813)
16. Just A, Arendshorst WJ,. Dynamics and contribution of mechanisms mediating renal blood flow autoregulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003; 285: R619-631. (Pubitemid 37040570)
17. Just A, Arendshorst WJ,. Nitric oxide blunts myogenic autoregulation in rat renal but not skeletal muscle circulation via tubuloglomerular feedback. J. Physiol. 2005; 569: 959-74. (Pubitemid 41830236)
18. Kleinstreuer N, David T, Plank MJ, Endre Z,. Dynamic myogenic autoregulation in the rat kidney: A whole-organ model. Am. J. Physiol. Renal Physiol. 2008; 294: F1453-1464.
19. Hayashi K, Epstein M, Loutzenhiser R, Forster H,. Impaired myogenic responsiveness of the afferent arteriole in streptozotocin-induced diabetic rats: Role of eicosanoid derangements. J. Am. Soc. Nephrol. 1992; 2: 1578-86.
20. Bell TD, Wang Y, Brands MW,. Mechanisms for renal blood flow control early in diabetes as revealed by chronic flow measurement and transfer function analysis. J. Am. Soc. Nephrol. 2006; 17: 2184-92. (Pubitemid 44141908)
21. Hashimoto Y, Ideura T, Yoshimura A, Koshikawa S,. Autoregulation of renal blood flow in streptozocin-induced diabetic rats. Diabetes 1989; 38: 1109-13. (Pubitemid 19250395)
22. Vallon V, Blantz RC, Thomson S,. Homeostatic efficiency of tubuloglomerular feedback is reduced in established diabetes mellitus in rats. Am. J. Physiol. 1995; 269: F876-883. (Pubitemid 26026122)
23. Wang X, Aukland K, Bostad L, Iversen BM,. Autoregulation of total and zonal glomerular filtration rate in spontaneously hypertensive rats with mesangiolysis. Kidney Blood Press. Res. 1997; 20: 11-7. (Pubitemid 27246521)
24. Derylo B, Babazono T, Glogowski E, Kapor-Drezgic J, Hohman T, Whiteside C,. High glucose-induced mesangial cell altered contractility: Role of the polyol pathway. Diabetologia 1998; 41: 507-15. (Pubitemid 28206819)
25. Hurst RD, Stevanovic ZS, Munk S, et al,. Glomerular mesangial cell altered contractility in high glucose is Ca2+ independent. Diabetes 1995; 44: 759-66.
26. Seino S, Shibasaki T, Minami K,. Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J. Clin. Invest. 2001; 121: 2118-25.
27. Cerasi E, Luft R,. The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus. Acta Endocrinol. (Copenh.) 1967; 55: 278-304.
28. Henquin JC,. Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 2000; 49: 1751-60.
29. Sun X, Gao C,. Imaging the effects of propofol on human cerebral glucose metabolism using positron emission tomography. J. Int. Med. Res. 2008; 36: 1305-10.
30. Penicaud L, Leloup C, Lorsignol A, Alquier T, Guillod E,. Brain glucose sensing mechanism and glucose homeostasis. Curr. Opin. Clin. Nutr. Metab. Care 2002; 5: 539-43. (Pubitemid 40684650)
31. Nordquist L, Palm F,. Diabetes-induced alterations in renal medullary microcirculation and metabolism. Curr. Diabetes Rev. 2007; 3: 53-65. (Pubitemid 46592794)
32. Eckardt KU, Bernhardt WM, Weidemann A, et al,. Role of hypoxia in the pathogenesis of renal disease. Kidney Int. Suppl. 2005; 99: S46-51.
33. Brezis M, Rosen S,. Hypoxia of the renal medulla-its implications for disease. N. Engl. J. Med. 1995; 332: 647-55.
34. Menini S, Iacobini C, Oddi G, et al,. Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: Role in the development of diabetic glomerular disease. Diabetologia 2007; 50: 2591-9. (Pubitemid 350060642)
35. Park SH, Choi HJ, Lee JH, Woo CH, Kim JH, Han HJ,. High glucose inhibits renal proximal tubule cell proliferation and involves PKC, oxidative stress, and TGF-beta 1. Kidney Int. 2001; 59: 1695-705.
36. Efrati S, Berman S, Tov YS, Averbukh Z, Weissgarten J,. Hyperglycemia alters renal cell responsiveness to pressure in a model of malignant hypertension. J. Hypertens. 2009; 27: 365-75.
37. Kane CD, Greenhalgh DG,. Expression and localization of p53 and bcl-2 in healing wounds in diabetic and nondiabetic mice. Wound Repair Regen. 2000; 8: 45-58. (Pubitemid 30140799)
38. Ziyadeh FN,. Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy. Diabetes Res. Clin. Pract. 2008; 82 (Suppl 1): S38-41.
39. Shrader CD, Bailey KM, Konat GW, Cilento EV, Reilly FD,. Insulin enhances proliferation and viability of human umbilical vein endothelial cells. Arch. Dermatol. Res. 2009; 301: 159-66.
40. Gandhi GY, Nuttall GA, Abel MD, et al,. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clin. Proc. 2005; 80: 862-6. (Pubitemid 40911459)