Development and a practical synthesis of the JAK2 inhibitor LY2784544

Organic Process Research and Development

Volumn 16, Issue 1, 2012, Pages 70-81

  Mitchell, David ^a   Cole, Kevin P ^a   Pollock, Patrick M ^a   Coppert, David M ^a   Burkholder, Timothy P ^a   Clayton, Joshua R ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLATION REACTIONS; BENZYLIC; BENZYLIC AMINES; BOND FORMING; DEOXYGENATIONS; DERIVATIZATIONS; HIGH YIELD; LARGE-SCALE PRODUCTION; MORPHOLINES; PALLADIUM-CATALYZED AMINATION; PROTECTING GROUP; PYRAZOLES; RESEARCH AND DEVELOPMENT; ROUTE SELECTION; SYNTHESIS ROUTE;

AMINATION; CATALYSIS; KETONES; ORGANIC COMPOUNDS; PILOT PLANTS; VANADIUM;

SYNTHESIS (CHEMICAL);

EID: 84856185942     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200229j     Document Type: Article

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