Beyond effect size: Consideration of the minimum effect size of interest in anesthesia trials

Anesthesia and Analgesia

Volumn 114, Issue 2, 2012, Pages 471-475

  Gibbs, Neville M ^a   Weightman, William M ^a  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHESIA; ARTICLE; CLINICAL TRIAL (TOPIC); HUMAN; INFERENTIAL STATISTICS; NULL HYPOTHESIS; OUTCOME ASSESSMENT; OUTCOMES RESEARCH; PRIORITY JOURNAL; SAMPLE SIZE; STATISTICAL SIGNIFICANCE; STUDY DESIGN;

ANESTHESIA; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CLINICAL TRIALS AS TOPIC; DATA INTERPRETATION, STATISTICAL; ENDPOINT DETERMINATION; EVIDENCE-BASED MEDICINE; HEART RATE; HUMANS; HYPERTENSION; INTUBATION, INTRATRACHEAL; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84856163851     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e31823d2ab7     Document Type: Article

References (30)

1. Katz MH. Study Design and Statistical Analysis. A Practical Guide for Clinicians. Cambridge: Cambridge University Press, 2006;127-40
2. Kusuoka H, Hoffman JIE. Advice on statistical analysis for circulation research. Circ Res 2002;91:662-71 (Pubitemid 35204948)
3. Husler J, Wernecke K-D. How to design trials/studies. In: Zbinden AM, Thomson D, Eds. Conducting Research in Anaesthesia and Intensive Care Medicine. Oxford: Butterworth Heinemann, 2001;97-138
4. Myles PS, Gin T. Statistical Methods for Anaesthesia and Intensive Care. Edinburgh: Butterworth Heinemann, 2000;19-31
5. Daly LE. Confidence intervals and sample sizes. In: Altman DG, Machin D, Bryant TN, Gardner MJ, Eds. Statistics with Confidence. 2nd ed. Bristol: BMJ Books, 2000;139-52
6. Goodman SN, Berlin JA. The use of predicted confidence intervals when planning experiments and the misuse of power when interpreting results. Ann Intern Med 1994;121:200-6 (Pubitemid 24225638)
7. Hintze J. NCSS. Kaysville, UT, 2007 (www.NCSS.com)
8. Goodman SN. A comment on replication, P values and evidence. StatMed 1992;11:875-9
9. O'Neill RT. Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear significance. Control Clin Trials 1997;18:550-6
10. Flood P. Primary versus secondary outcomes in gargantuan studies. Anesthesiology 2009;111:704-5
11. Rigg JRA, Jamrozik K, Myles PS, Silbert BS, Peyton PJ, Parsons RW, Collins KS. Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial. Lancet 2002;359:1276-82 (Pubitemid 34310632)
12. Apfel CC, Kranke P, Katz MH, Goepfert C, Papenfuss T, Rauch S, Heineck R, Greim C-A, Roewer N. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design. Br J Anaesth 2002;88:659-68 (Pubitemid 34498594)
13. Myles PS, Leslie K, McNeil J, Forbes A, Chan MTV. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet 2004;363:1757-63 (Pubitemid 38698378)
14. Moller AM, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet 2002;359:114-7 (Pubitemid 34112539)
15. De Hert SG, ten Broeke PW, Mertens E, Van Sommeren EW, De Blier IG, Stockman BA, Rodrigus IE. Sevoflurane but not propofol preserves myocardial function in coronary surgery patients. Anesthesiology 2002;97:42-9 (Pubitemid 34733920)
16. Monk TG, Saini V, Weldon BC, Sigl JC. Anesthetic management and one-year mortality after noncardiac surgery. Anesth Analg 2005;100:4-10 (Pubitemid 40013594)
17. Carli F, Mayo N, Klubien K, Schricker T, Trudel J, Belliveau P. Epidural analgesia enhances functional exercise capacity and health-related quality of life after colonic surgery: results of a randomized trial. Anesthesiology 2002;97:540-9 (Pubitemid 34977311)
18. Scott NB, Turfrey D, Ray D, Nzewi O, Sutcliffe NP, Lal AB, Norrie J, Nagels W, Ramayya GP. A prospective randomized study of the potential benefits of thoracic epidural anesthesia and analgesia in patients undergoing coronary artery bypass grafting. Anesth Analg 2001;93:528-35 (Pubitemid 32783271)
19. Apfel CC, Kortilla K, Abdalla M, Kerger H, Turan A, Vedder I, Zernak C, Danner K, Jokela R, Pocock SJ, Trenkler S, Kredel M, Biedler A, Sessler DI, Roewer N. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004;350:2441-51
20. Brimacombe J, Keller C, Fullekrug B, Agro F, Rosenblatt W, Dierdorf SF, Garcia de Lucas E, Capdevilla X, Brimacombe N. A multicenter study comparing the ProsealTM and ClassicTM laryngeal mask airway in anesthetized, nonparalyzed patients. Anesthesiology 2002;96:289-95 (Pubitemid 34121735)
21. Fassoulaki A, Patris K, Sarantopoulos C, Hogan Q. The analgesic effect of gabapentin and mexiletine after breast surgery for cancer. Anesth Analg 2002;95:985-91
22. Norris EJ, Beattie C, Perler BA, Martinez EA, Meinert CL, Anderson GF, Grass JA, Sakima NT, Gorman R, Achuff SC, Martin BK, Minken SL, Williams GM, Traystman. Double masked randomized trial comparing alternate combinations of intraoperative anesthesia and postoperative analgesia in abdominal aortic surgery. Anesthesiology 2001;95:1054-67 (Pubitemid 33043217)
23. Struys MMRF, De Smet T, Versichelen LFM, Van de Velde S, Van den Broecke R, Mortier EP. Comparison of closed-loop controlled administration of propofol using bispectral index as the controlled variable versus "standard practice" controlled administration. Anesthesiology 2001;95:6-17 (Pubitemid 32622990)
24. Cook TM, Nolan JP, Verghese C, Strube PJ, Lees M, Millar JM, Baskett PJF. Randomized crossover comparison of the ProSeal with the classic laryngeal mask airway in paralysed anaesthetized patients. Br J Anaesth 2002;88:527-33 (Pubitemid 34285203)
25. Bannister CF, Brosius KK, Sigl JC, Meyer BJ, Sebel PS. The effect of bispectral index monitoring on anesthetic use and recovery in children anesthetized with sevoflurane in nitrous oxide. Anesth Analg 2001;92:877-81
26. Avidan MS, Zhang L, Burnside BA, Finkel KJ, Searleman AC, Selvidge JA, Saager L, Turner MS, Rao S, Bottros M, Hantler C, Jacobsohn E, Evers AS. Anesthesia awareness and the bispectral index. N Engl J Med 2008;358:1097-108 (Pubitemid 351398484)
27. Willams SR, Chouinard P, Arcand G, Harris P, Ruel M, Boudreault D, Girad F. Ultrasound guidance speeds execution and improves the quality of supraclavicular block. Anesth Analg 2003;97:1518-23 (Pubitemid 37310160)
28. Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology 2002;97:1582-90 (Pubitemid 35417460)
29. Rossaint R, Reyle-Hahn M, Schulteamesch J, Scholz J, Scherpereel P, Vallet B, Giunta F, Del Turco M, Erdmann W, Tenbrinck R, Hammerle AF, Nagele P. Multicenter randomized comparison of the efficacy and safety of xenon and isoflurane in patients undergoing elective surgery. Anesthesiology 2003;98:6-13 (Pubitemid 36043402)
30. Hausenloy DJ, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM. Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial. Lancet 2007;370:575-9 (Pubitemid 47247853)