Identifying missed opportunities for early intervention among HIV-infected paediatric admissions at Chris Hani Baragwanath hospital, Soweto, South Africa

Southern African Journal of HIV Medicine

Volumn , Issue 42, 2011, Pages 16-23

  Dramowski, Angela ^a   Coovadia, Ashraf ^b   Meyers, Tammy ^c   Goga, Ameena ^d  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; COTRIMOXAZOLE; NEVIRAPINE;

ANTIBIOTIC PROPHYLAXIS; ANTIVIRAL THERAPY; ARTICLE; CAUSE OF DEATH; CHILD; CHILD HOSPITALIZATION; CROSS-SECTIONAL STUDY; CYTOMEGALOVIRUS INFECTION; CYTOMEGALOVIRUS PNEUMONITIS; EARLY DIAGNOSIS; EARLY INFANT DIAGNOSIS; EARLY INTERVENTION; FEMALE; HEALTH CARE UTILIZATION; HOSPITAL ADMISSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN IMMUNODEFICIENCY VIRUS PREVALENCE; INFANT; INFECTION PREVENTION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PNEUMOCYSTIS PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PREVENTION OF MOTHER TO CHILD TRANSMISSION; RETROSPECTIVE STUDY; SOUTH AFRICA; STREPTOCOCCUS PNEUMONIAE;

EID: 84856144496     PISSN: 16089693     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. UNAIDS World Health Organisation. Global report: UNAIDS report on the global AIDS epidemic 2010. http.//wwwunaids.org/documents/20101123-GlobalReport- empdf (accessed 1 December 2010).
2. Rogerson SR, Gladstone M, Callaghan M, et al. HIV infection among paediatric in-patients in Blantyre, Malawi. Trans R Soc Trop Med Hyg 2004;98(9):544-552. (Pubitemid 38987091)
3. Bradshaw D, Chopra M, Kerber K, et al. Every death counts: use of mortality audit data for decision making to save the lives of mothers, babies, and children in South Africa. Lancet 2008;371:1294-1304.
4. ChildInfo. Monitoring the situation of children and women: Trends in underfive mortality rates (1960-2008). 2010. http://wwwunicef.org/infobycountry/ southafrica-statistics.html (accessed 1 December 2010).
5. Bourne DE, Thompson M, Brody LL, et al. Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa. AIDS 2009;23(1):101-106.
6. Newell ML, Coovadia H, Cortina-Borja M, Rollins N, Gaillard P, Dabis F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet 2004;364:1236-1243. (Pubitemid 39311344)
7. South African National Department of Health. Guidelines For the Management of HIV-infected Children. Pretoria: Jacana Media, 2005.
8. Meyers T, Moultrie H, Naidoo K, Cotton M, Eley B, Sherman G. Challenges to pediatric HIV care and treatment in South Africa. J Infect Dis 2007;196(suppl 3):S474-481. (Pubitemid 351417241)
9. Kellerman S, Essajee S. HIV testing for children in resource-limited settings: what are we waiting for? PLoS Med 2010;7(7):e1000285.
10. Finlayson H, Eley B. Treatment and outcome of hositalised, very young, HIV-infected children. South African Journal of Child Health 2007;1(4):140-144.
11. Patrick M, Stephen C Child PIP: Making mortality meaningful by using a structured mortality review process to improve the quality of care that children receive in the South African health system. South African Journal of Child Health 2008;2(2):38-42.
12. Zwi K, Pettifor J, Soderlund N, Meyers T. HIV infection and in-hospital mortality at an academic hospital in South Africa. Arch Dis Child 2000;83(3):227-230.
13. Meyers TM, Pettifor JM, Gray GE, Crewe-Brown H, Galpin JS. Pediatric admissions with human immunodeficiency virus infection at a regional hospital in Soweto, South Africa. J Trop Pediatr 2000;46(4):224-230. (Pubitemid 30614558)
14. Statistics South Africa.Mid-year population estimates. 2010. http://wwwstatssa.govza/publications/P0302/P03022010.pdf (accessed 6 November 2011).
15. WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. 2007. wwwwhoint/hiv/pub/guidelines/HIVstaging150307.pdf (accessed 6 November 2011).
16. Fatti GL, Zar HJ, Swingler GH. Clinical indicators of Pneumocystis jiroveci pneumonia (PCP) in South African children infected with the human immunodeficiency virus. Int J Infect Dis 2006;10(4):282-285 (Pubitemid 44183714)
17. Wijesingha S, Graham S. Evidence behind the WHO guidelines: hospital care for children. What are the clinical indicators of PCP? J Trop Pediatr 2007;53(1):4-7. (Pubitemid 46195887)
18. 2006 WHO Child Growth Standards. wwwwho.int/childgrowth/standards/en/ (accessed 4 February 2011).
19. Antenatal Survey 2009: National Antenatal Sentinel HIV and Syphilis Prevalence Survey in South Africa, 2009. Pretoria: National Department of Health, 2010. http://wwwhstorgza/healthstats/13/data (accessed 10 May 2011).
20. Moodley D, Esterhuizen TM, Pather T, Chetty V, Ngaleka L. High HIV incidence during pregnancy: compelling reason for repeat HIV testing. AIDS 2009;23(10):1255-1259.
21. Sherman GG, Jones SA, Coovadia AH, Urban MF, Bolton KD. PMTCT from research to reality - results from a routine service. S Afr Med J 2004;94(4):289-292. (Pubitemid 38585224)
22. Coetzee D, Hilderbrand K, Boulle A, Draper B, Abdullah F, Goemaere E. Effectiveness of the first district-wide programme for the prevention of mother-to-child transmission of HIV in South Africa. Bull World Health Organ 2005;83(7):489-494. (Pubitemid 41003323)
23. Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008;359(21):2233-2244.
24. Maree L, van Zyl GU, Lotter SL, de Beer C, Esser MM, Preiser W. Young age a predictor of weak reactivity in a rapid antibody test in infants infected with HIV. J Med Virol 2010;82(8):1314-1317.
25. Countdown to 2015 Maternal, Newborn and Child Health - Country Profiles - South Africa, 2008 Report. http//www- countdown2015mnch.org/documents/ countryprofiles/south-africa-20080312.pdf (accessed 12 June 2010).
26. Puthanakit T, Aurpibul L, Oberdorfer P, et al. Hospitalization and mortality among HIV-infected children after receiving highly active antiretroviral therapy. Clin Infect Dis 2007;44(4):599-604. (Pubitemid 46233267)
27. Chopra M, Daviaud E, Pattinson R, Fonn S, Lawn JE Saving the lives of South Africa's mothers, babies, and children: can the health system deliver? Lancet 2009;374(9692):835-846.