Permeability of peritoneal and glomerular capillaries: What are the differences according to pore theory?

Peritoneal Dialysis International

Volumn 31, Issue 3, 2011, Pages 249-258

  Rippe, Bengt ^a   Davies, Simon ^b  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY HOSPITAL OF NORTH STAFFORDSHIRE   (United Kingdom)

Author keywords

Capillary permeability; Ficoll; Glomerular filtration; Interendothelial cleft; Molecular charge; Molecular flexibility; Peritoneal transport

Indexed keywords

ALBUMIN; AQUAPORIN; DEXTRAN; DEXTRAN SULFATE; FICOLL;

ANION EXCHANGE; BLOOD VESSEL DIAMETER; BLOOD VESSEL TONE; CAPILLARY FLOW; CAPILLARY PERMEABILITY; CATION EXCHANGE; GLOMERULAR FILTRATION BARRIER; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; GLYCOCALYX; HUMAN; MEMBRANE TRANSPORT; MOLECULAR SIZE; NONHUMAN; PERITONEAL CAVITY; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN TRANSPORT; REVIEW; TISSUE STRUCTURE;

ANIMALS; CAPILLARIES; CAPILLARY PERMEABILITY; ELECTROPHYSIOLOGICAL PROCESSES; HUMANS; KIDNEY GLOMERULUS; PERITONEUM;

EID: 84856137894     PISSN: 08968608     EISSN: 17184304     Source Type: Journal    
DOI: 10.3747/pdi.2010.00124     Document Type: Review

References (63)

1. Pavenstädt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev 2003; 83:253-307.
2. Haraldsson B, Nyström J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 2008; 88:451-87.
3. Venturoli D, Rippe B. Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability. Am J Physiol Renal Physiol 2005; 288:F605-13.
4. Kestilä M, Lenkkeri U, Männikkö M, Lamerdin J, McCready P, Putaala H, et al. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol Cell 1998; 1:575-82.
5. Axelsson J, Rippe A, Venturoli D, Swärd P, Rippe B. Effects of early endotoxemia and dextran-induced anaphylaxis on the size selectivity of the glomerular filtration barrier in rats. Am J Physiol Renal Physiol 2009; 296:F242-8.
6. Axelsson J, Rippe A, Rippe B. Acute hyperglycemia induces rapid, reversible increases in glomerular permeability in nondiabetic rats. Am J Physiol Renal Physiol 2010; 298:F1306-12.
7. Peti-Peterdi J, Sipos A. A high-powered view of the filtration barrier. J Am Soc Nephrol 2010; 21:1835-41.
8. Rippe B, Stelin G. Simulations of peritoneal solute transport during continuous ambulatory peritoneal dialysis (CAPD). Application of two-pore formalism. Kidney Int 1989; 35:1234-44.
9. Rippe B, Stelin G, Haraldsson B. Computer simulations of peritoneal fluid transport in CAPD. Kidney Int 1991; 40:315-25.
10. Rippe B, Levin L. Computer simulations of ultrafiltration profiles for an icodextrin-based peritoneal fluid in CAPD. Kidney Int 2000; 57:2546-56.
11. Waniewski J, Stachowska-Pietka J, Flessner MF. Distributed modeling of osmotically driven fluid transport in peritoneal dialysis: theoretical and computational investigations. Am J Physiol Heart Circ Physiol 2009; 296:H1960-8.
12. Stachowska-Pietka J, Waniewski J, Flessner MF, Lindholm B. Distributed model of peritoneal fluid absorption. Am J Physiol Heart Circ Physiol 2006; 291:H1862-74.
13. Renkin EM, Gilmore JP. Glomerular filtration. In: Geiger SR, ed. Handbook of Physiology. Section 8: Renal Physiology. Orloff J, Berliner RW, section eds. Washington, DC: American Physiological Society; 1973: 185-248.
14. Rippe B, Haraldsson B. Transport of macromolecules across microvascular walls: the two-pore theory. Physiol Rev 1994; 74:163-219.
15. Lund U, Rippe A, Venturoli D, Tenstad O, Grubb A, Rippe B. Glomerular filtration rate dependence of sieving of albumin and some neutral proteins in rat kidneys. Am J Physiol Renal Physiol 2003; 284:F1226-34.
16. Krediet RT, Koomen GC, Koopman MG, Hoek FJ, Struijk DG, Boeschoten EW, et al. The peritoneal transport of serum proteins and neutral dextran in CAPD patients. Kidney Int 1989; 35:1064-72.
17. Buis B, Koomen GC, Imholz AL, Struijk DG, Reddingius RE, Arisz L, et al. Effect of electric charge on the transperitoneal transport of plasma proteins during CAPD. Nephrol Dial Transplant 1996; 11:1113-20.
18. Asgeirsson D, Axelsson J, Rippe C, Rippe B. Similarity of permeabilities for Ficoll, pullulan, charge-modified albumin and native albumin across the rat peritoneal membrane. Acta Physiol (Oxf) 2009; 196:427-33.
19. Vyas SV, Comper WD. Dextran sulfate binding to isolated rat glomeruli and glomerular basement membrane. Biochim Biophys Acta 1994; 1201:367-72.
20. Axelsson J, Mahmutovic I, Rippe A, Rippe B. Loss of size selectivity of the glomerular filtration barrier in rats following laparotomy and muscle trauma. Am J Physiol Renal Physiol 2009; 297:F577-82.
21. Rippe C, Asgeirsson D, Venturoli D, Rippe A, Rippe B. Effects of glomerular filtration rate on Ficoll sieving coefficients (θ) in rats. Kidney Int 2006; 69:1326-32.
22. Jeansson M, Haraldsson B. Glomerular size and charge selectivity in the mouse after exposure to glucosaminoglycan-degrading enzymes. J Am Soc Nephrol 2003; 14:1756-65.
23. Asgeirsson D, Venturoli D, Fries E, Rippe B, Rippe C. Glomerular sieving of three neutral polysaccharides, polyethylene oxide and bikunin in rat. Effects of molecular size and conformation. Acta Physiol (Oxf) 2007; 191:237-46.
24. Rippe C, Rippe A, Larsson A, Asgeirsson D, Rippe B. Nature of glomerular capillary permeability changes following acute renal ischemia-reperfusion injury in rats. Am J Physiol Renal Physiol 2006; 291:F1362-8.
25. Brenner BM, Hostetter TH, Humes HD. Glomerular permselectivity: barrier function based on discrimination of molecular size and charge. Am J Physiol 1978; 234:F455-60.
26. Maddox DA, Deen WM, Brenner BM. Glomerular filtration. In: American Physiological Society. Handbook of Physiology. Section 8: Renal Physiology. Windhager EE, section ed. Vol. I. New York, NY: American Physiological Society; 1992: 545-638.
27. Tencer J, Frick IM, Öqvist BW, Alm P, Rippe B. Size-selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of shunt pathways. Kidney Int 1998; 53:709-15.
28. Curry FE, Michel CC. A fiber matrix model of capillary permeability. Microvasc Res 1980; 20:96-9.
29. Adamson RH, Lenz JF, Zhang X, Adamson GN, Weinbaum S, Curry FE. Oncotic pressures opposing filtration across non-fenestrated rat microvessels. J Physiol 2004; 557:889-907.
30. Farquhar MG, Kanwar YS. Characterization of anionic sites in the glomerular basement membranes of normal and nephrotic rats. In: Leaf A, Giebish G, Bolis L, Gorini S, eds. Renal Pathophysiology. New York, NY: Raven Press; 1980: 57-74.
31. Bundgaard M. The three-dimensional organization of tight junctions in a capillary endothelium revealed by serial-section electron microscopy. J Ultrastruct Res 1984; 88:1-17.
32. Adamson RH, Michel CC. Pathways through the intercellular clefts of frog mesenteric capillaries. J Physiol 1993; 466:303-27.
33. Curry FR. Microvascular solute and water transport. Microcirculation 2005; 12:17-31.
34. Rosengren BI, Rippe A, Rippe C, Venturoli D, Swärd K, Rippe B. Transvascular protein transport in mice lacking endothelial caveolae. Am J Physiol Heart Circ Physiol 2006; 291:H1371-7.
35. Rostgaard J, Qvortrup K. Sieve plugs in fenestrae of glomerular capillaries-site of the filtration barrier? Cells Tissues Organs 2002; 170:132-8.
36. Tryggvason K. Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm. J Am Soc Nephrol 1999; 10:2440-5.
37. Rippe B, Krediet RT. Peritoneal physiology-transport of solutes. In: Gokal RC, Nolph DK, eds. The Textbook of Peritoneal Dialysis. Dordrecht, Netherlands: Kluwer Academic Publishers; 1994: 68-132.
38. Haraldsson B, Ekholm C, Rippe B. Importance of molecular charge for the passage of endogenous macromolecules across continuous capillary walls, studied by serum clearance of lactate dehydrogenase (LDH) isoenzymes. Acta Physiol Scand 1983; 117:123-30.
39. Adamson RH, Huxley VH, Curry FE. Single capillary permeability to proteins having similar size but different charge. Am J Physiol 1988; 254:H304-12.
40. Perry MA, Benoit JN, Kvietys PR, Granger DN. Restricted transport of cationic macromolecules across intestinal capillaries. Am J Physiol 1983; 245:G568-72.
41. Pietra GG, Fishman AP, Lanken PN, Sampson P, Hansen-Flaschen J. Permeability of pulmonary endothelium to neutral and charged macromolecules. Ann N YAcad Sci 1982; 401:241-7.
42. Parker JC, Gilchrist S, Cartledge JT. Plasma-lymph exchange and interstitial distribution volumes of charged macromolecules in the lung. J Appl Physiol 1985; 59:1128-36.
43. Gilchrist SA, Parker JC. Exclusion of charged macromolecules in the pulmonary interstitium. Microvasc Res 1985; 30:88-98.
44. Bohrer MP, Baylis C, Humes HD, Glassock RJ, Robertson CR, Brenner BM. Permselectivity of the glomerular capillary wall. Facilitated filtration of circulating polycations. J Clin Invest 1978; 61:72-8.
45. Chang RL, Deen WM, Robertson CR, Brenner BM. Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions. Kidney Int 1975;8:212-18.
46. Tay M, Comper WD, Singh AK. Charge selectivity in kidney ultrafiltration is associated with glomerular uptake of transport probes. Am J Physiol 1991; 260:F549-54.
47. Guasch A, Deen WM, Myers BD. Charge selectivity of the glomerular filtration barrier in healthy and nephrotic humans. J Clin Invest 1993; 92:2274-82.
48. Bolton GR, Deen WM, Daniels BS. Assessment of the charge selectivity of glomerular basement membrane using Ficoll sulfate. Am J Physiol 1998; 274:F889-96.
49. Schaeffer RC Jr, Gratrix ML, Mucha DR, Carbajal JM. The rat glomerular filtration barrier does not show negative charge selectivity. Microcirculation 2002; 9:329-42.
50. Guimarães MA, Nikolovski J, Pratt LM, Greive K, Comper WD. Anomalous fractional clearance of negatively charged Ficoll relative to uncharged Ficoll. Am J Physiol Renal Physiol 2003; 285:F1118-24.
51. Asgeirsson D, Venturoli D, Rippe B, Rippe C. Increased glomerular permeability to negatively charged Ficoll relative to neutral Ficoll in rats. Am J Physiol Renal Physiol 2006; 291:F1083-9.
52. Groszek J, Li L, Ferrell N, Smith R, Zorman CA, Hofmann CL, et al. Molecular conformation and filtration properties of anionic Ficoll. Am J Physiol Renal Physiol 2010; 299:F752-7.
53. Comper WD, Glasgow EF. Charge selectivity in kidney ultrafiltration. Kidney Int 1995; 47:1242-51.
54. Lindström KE, Blom A, Johnsson E, Haraldsson B, Fries E. High glomerular permeability of bikunin despite similarity in charge and hydrodynamic size to serum albumin. Kidney Int 1997; 51:1053-8.
55. Bohrer MP, Deen WM, Robertson CR, Troy JL, Brenner BM. Influence of molecular configuration on the passage of macromolecules across the glomerular capillary wall. J Gen Physiol 1979; 4:583-93.
56. Deen WM, Lazzara MJ, Myers BD. Structural determinants of glomerular permeability. Am J Physiol Renal Physiol 2001; 281:F579-96.
57. Rennke HG, Venkatachalam MA. Glomerular permeability of macromolecules. Effect of molecular configuration on the fractional clearance of uncharged dextran and neutral horseradish peroxidase in the rat. J Clin Invest 1979; 63:713-17.
58. Hemmelder MH, de Jong PE, de Zeeuw D. A comparison of analytic procedures for measurement of fractional dextran clearances. J Lab Clin Med 1998; 132:390-403.
59. Fissell WH, Manley S, Dubnisheva A, Glass J, Magistrelli J, Eldridge AN, et al. Ficoll is not a rigid sphere. Am J Physiol Renal Physiol 2007; 293:F1209-13.
60. Fissell WH, Hofmann CL, Smith R, Chen MH. Size and conformation of Ficoll as determined by size-exclusion chromatography followed by multiangle light scattering. Am J Physiol Renal Physiol 2009; 298:F205-8.
61. Davies SJ. Longitudinal relationship between solute transport and ultrafiltration capacity in peritoneal dialysis patients. Kidney Int 2004; 66:2437-45.
62. Rippe B, Venturoli D. Simulations of osmotic ultrafiltration failure in CAPD using a serial three-pore membrane/fiber matrix model. Am J Physiol Renal Physiol 2007; 292:F1035-43.
63. Perl J, Huckvale K, Chellar M, John B, Davies SJ. Peritoneal protein clearance and not peritoneal membrane transport status predicts survival in a contemporary cohort of peritoneal dialysis patients. Clin J Am Soc Nephrol 2009; 4:1201-6.