GM-CSF-independent CD1a expression in epidermal langerhans cells: Evidence from human CD1A genome-transgenic mice

Journal of Investigative Dermatology

Volumn 132, Issue 1, 2012, Pages 241-244

  Kobayashi, Chisa ^a   Shiina, Takashi ^b   Tokioka, Atsuko ^c   Hattori, Yuki ^a   Komori, Takaya ^a   Kobayashi Miura, Mikiko ^b   Takizawa, Toshihiro ^d   Takahara, Kazuhiko ^a   Inaba, Kayo ^a   Inoko, Hidetoshi ^b   Takeya, Motohiro ^e   Dranoff, Glenn ^f   Sugita, Masahiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHIMANE UNIVERSITY   (Japan)

^d NIPPON MEDICAL SCHOOL   (Japan)

^e KUMAMOTO UNIVERSITY   (Japan)

^f DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; T6 ANTIGEN;

ANTIGEN EXPRESSION; CD1A GENE; CELL DIFFERENTIATION; EPIDERMIS; FLOW CYTOMETRY; GENE; GENE EXPRESSION REGULATION; GENOME; LANGERHANS CELL; LETTER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

EID: 84856116322     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.280     Document Type: Letter

References (9)

1. Caux C, Dezutter-Dambuyant C, Schmitt D et al. (1992) GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Nature 360:258-61
2. De Jong A, Pena-Cruz V, Cheng TY et al. (2010) CD1a-autoreactive T cells are a normal component of the human alphabeta T cell repertoire. Nat Immunol 11:1102-9
3. Dranoff G, Crawford AD, Sadelain M et al. (1994) Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 264:713-6 (Pubitemid 24185882)
4. Geissmann F, Prost C, Monnet JP et al. (1998) Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. J Exp Med 187:961-6 (Pubitemid 28141669)
5. Hunger RE, Sieling PA, Ochoa MT et al. (2004) Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. J Clin Invest 113:701-8 (Pubitemid 38544163)
6. Metcalf D (2008) Hematopoietic cytokines. Blood 111:485-91
7. Mohamadzadeh M, Berard F, Essert G et al. (2001) Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med 194: 1013-20
8. Pena-Cruz V, Ito S, Dascher CC et al. (2003) Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. J Invest Dermatol 121:517-21 (Pubitemid 37072263)
9. Sugita M, Grant EP, van Donselaar E et al. (1999) Separate pathways for antigen presentation by CD1molecules. Immunity 11:743-52 (Pubitemid 30030713)