Toddlers with anasarca and severe anemia: A lesson in preventive medicine

Current Opinion in Pediatrics

Volumn 24, Issue 1, 2012, Pages 129-133

  Salstrom, Jennifer L ^a   Kent, Michael ^a   Liang, Xiayuan ^a   Wang, Michael ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

anasarca; anemia; edema; enteropathy; hypoalbuminemia; hypoproteinemia; iron

Indexed keywords

IRON;

ANASARCA; CASE REPORT; CHILD; DISEASE SEVERITY; EARLY DIAGNOSIS; EARLY INTERVENTION; HUMAN; HYPOALBUMINEMIA; HYPOPROTEINEMIA; IRON DEFICIENCY ANEMIA; LABORATORY DIAGNOSIS; MALE; NUTRITIONAL DEFICIENCY; PRACTICE GUIDELINE; PRESCHOOL CHILD; PREVENTIVE MEDICINE; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; PROTEIN LOSING GASTROENTEROPATHY; REVIEW; VITAMIN SUPPLEMENTATION;

ANEMIA, IRON-DEFICIENCY; CHILD, PRESCHOOL; EDEMA; HUMANS; HYPOALBUMINEMIA; HYPOPROTEINEMIA; INFANT; PROTEIN-LOSING ENTEROPATHIES;

EID: 84856115442     PISSN: 10408703     EISSN: 1531698X     Source Type: Journal    
DOI: 10.1097/MOP.0b013e32834dfc92     Document Type: Review

References (34)

1. Baker RD, Greer FR. Diagnosis and prevention of iron deficiency and irondeficiency anemia in infants and young children (0-3 years of age). Pediatrics 2010; 126:1040-1050. This review summarizes important clinical data regarding IDA and provides updated AAP guidelines regarding the treatment and prevention of IDA in children.
2. Zimmermann MB, Hurrell RF. Nutritional iron deficiency. Lancet 2007; 370:511-520. (Pubitemid 47214636)
3. Naiman JL, Oski FA, Diamond LK, et al. The gastrointestinal effects of irondeficiency anemia. Pediatrics 1964; 33:83-99.
4. Woodruff CW, Wright SW, Wright RP. The role of fresh cow's milk in iron deficiency. II. Comparison of fresh cow's milk with a prepared formula. Am J Dis Child 1972; 124:26-30.
5. Woodruff CW, Clark JL. The role of fresh cow's milk in iron deficiency. I. Albumin turnover in infants with iron deficiency anemia. Am J Dis Child 1972; 124:18-23.
6. Lundstrom U, Perkkio M, Savilahti E, Siimes M. Iron deficiency anaemia with hypoproteinaemia. Arch Dis Child 1983; 58:438-441. (Pubitemid 13056486)
7. Iron-deficiency anemia with hypoproteinemia in an infant. Nutr Rev 1989; 47:48-50.
8. Nickerson HJ, Silberman T, Park RW, et al. Treatment of iron deficiency anemia and associated protein-losing enteropathy in children. J Pediatr Hematol Oncol 2000; 22:50-54. (Pubitemid 32266838)
9. Hamrick HJ. Whole cow's milk, iron deficiency anemia, and hypoproteinemia: an old problem revisited. Arch Pediatr Adolesc Med 1994; 148:1351-1352. (Pubitemid 24375654)
10. Crossley JR, Elliott RB. Simple method for diagnosing protein-losing enteropathies. Br Med J 1977; 1:428-429. (Pubitemid 8023951)
11. Sakai Y, Sakai R, Yoshida N, Miyazaki S. Iron deficiency anemia and hypoproteinemia induced by fresh cow's milk [in Japanese]. Rinsho Ketsueki 1992; 33:1691-1696.
12. Savilahti E. Food-induced malabsorption syndromes. J Pediatr Gastroenterol Nutr 2000; 30 (Suppl):S61-S66. (Pubitemid 30366216)
13. Zamani F, Mohamadnejad M, Shakeri R, et al. Gluten sensitive enteropathy in patients with iron deficiency anemia of unknown origin. World J Gastroenterol 2008; 14:7381-7385.
14. Monzon H, Forne M, Gonzalez C, et al. Mild enteropathy as a cause of iron-deficiency anaemia of previously unknown origin. Dig Liver Dis 2011; 43:448-453.
15. Kosnai I, Kuitunen P, Siimes MA. Iron deficiency in children with celiac disease on treatment with gluten-free diet. Role of intestinal blood loss. Arch Dis Child 1979; 54:375-378. (Pubitemid 9158991)
16. Kalayci AG, Kanber Y, Birinci A, et al. The prevalence of coeliac disease as detected by screening in children with iron deficiency anaemia. Acta Paediatr 2005; 94:678-681. (Pubitemid 40839794)
17. Booth CC, Peters TJ, Doe WF. Immunopathology of coeliac disease. Ciba Found Symp 1977; 46:329-346.
18. Leon F, Sanchez L, Camarero C, Roy G. Cytokine production by intestinal intraepithelial lymphocyte subsets in celiac disease. Dig Dis Sci 2005; 50:593-600. (Pubitemid 40543754)
19. Kuitunen P, Savilahti E, Verkasalo M. Intestinal cow's milk allergy. Klin Padiatr 1985; 197:355-359.
20. Lebenthal E, Laor J, Lewitus Z, et al. Gastrointestinal protein loss in allergy to cow's milk beta-lactoglobulin. Isr J Med Sci 1970; 6:506-510.
21. Caffarelli C, Baldi F, Bendandi B, et al. Cow's milk protein allergy in children: a practical guide. Ital J Pediatr 2010; 36:5-11.
22. Kosnai I, Kuitunen P, Savilahti E, Sipponen P. Mast cells and eosinophils in the jejunal mucosa of patients with intestinal cow's milk allergy and celiac disease of childhood. J Pediatr Gastroenterol Nutr 1984; 3:368-372. (Pubitemid 14108908)
23. Katz AJ, Twarog FJ, Zeiger RS, Falchuk ZM. Milk-sensitive and eosinophilic gastroenteropathy: similar clinical features with contrasting mechanisms and clinical course. J Allergy Clin Immunol 1984; 74:72-78. (Pubitemid 14093029)
24. Ganz T. Molecular control of iron transport. J Am Soc Nephrol 2007; 18:394-400. (Pubitemid 46193304)
25. Lieu PT, Heiskala M, Peterson PA, Yang Y. The roles of iron in health and disease. Mol Aspects Med 2001; 22:1-87. (Pubitemid 32143801)
26. Wang J, Pantopoulos K. Regulation of cellular iron metabolism. Biochem J 2011; 434:365-381.
27. Chua AC, Graham RM, Trinder D, Olynyk JK. The regulation of cellular iron metabolism. Crit Rev Clin Lab Sci 2007; 44:413-459. (Pubitemid 47619398)
28. Watson WS, Morrison J, Bethel MI, et al. Food iron and lead absorption in humans. Am J Clin Nutr 1986; 44:248-256. (Pubitemid 16051496)
29. Wright RO, Shannon MW, Wright RJ, Hu H. Association between iron deficiency and low-level lead poisoning in an urban primary care clinic. Am J Public Health 1999; 89:1049-1053. (Pubitemid 30433942)
30. Wright RO, Tsaih SW, Schwartz J, et al. Association between iron deficiency and blood lead level in a longitudinal analysis of children followed in an urban primary care clinic. J Pediatr 2003; 142:9-14. (Pubitemid 36106380)
31. Lozoff B, Jimenez E, Wolf AW. Long-term developmental outcome of infants with iron deficiency. N Engl J Med 1991; 325:687-694.
32. Lozoff B, Jimenez E, Hagen J, et al. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics 2000; 105:E51.
33. McCann JC, Ames BN. An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function. Am J Clin Nutr 2007; 85:931-945. (Pubitemid 46557905)
34. Sherry B, Mei Z, Yip R. Continuation of the decline in prevalence of anemia in low-income infants and children in five states. Pediatrics 2001; 107:677-682. (Pubitemid 32273162)