Analysis of plasma ghrelin in patients with medium-chain acyl-CoA dehydrogenase deficiency and glutaric aciduria type II

European Journal of Endocrinology

Volumn 166, Issue 2, 2012, Pages 235-240

  Akamizu, Takashi ^a,b   Sakura, Nobuo ^c   Shigematsu, Yosuke ^d   Tajima, Go ^c   Ohtake, Akira ^e   Hosoda, Hiroshi ^f   Iwakura, Hiroshi ^b   Ariyasu, Hiroyuki ^b   Kangawa, Kenji ^f  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d UNIVERSITY OF FUKUI   (Japan)

^e SAITAMA MEDICAL UNIVERSITY   (Japan)

^f NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; GHRELIN;

ACYLATION; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME DEFICIENCY; FATTY ACID OXIDATION; FEMALE; GROWTH HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HORMONE SYNTHESIS; HUMAN; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE DEFICIENCY; MULTIPLE ACYL COA DEHYDROGENASE DEFICIENCY; PRESCHOOL CHILD; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCHOOL CHILD;

ACYL-COA DEHYDROGENASE; ADULT; BLOOD CHEMICAL ANALYSIS; CARNITINE; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GHRELIN; HUMANS; LIPID METABOLISM, INBORN ERRORS; MULTIPLE ACYL COENZYME A DEHYDROGENASE DEFICIENCY; PROTEIN PROCESSING, POST-TRANSLATIONAL; YOUNG ADULT;

EID: 84856096482     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-11-0785     Document Type: Article

References (29)

1. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H & Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999 402 656-660. (doi:10.1038/ 45230)
2. van der Lely AJ, Tschop M, Heiman ML & Ghigo E. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocrine Reviews 2004 25 426-457. (doi:10.1210/er. 2002-0029)
3. Korbonits M, Goldstone AP, Gueorguiev M & Grossman AB. Ghrelin - a hormone with multiple functions. Frontiers in Neuroendocrinology 2004 25 27-68. (doi:10.1016/j.yfrne.2004. 03.002)
4. Hosoda H, Kojima M, Mizushima T, Shimizu S & Kangawa K. Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing. Journal of Biological Chemistry 2003 278 64-70. (doi:10. 1074/jbc.M205366200)
5. Nishi Y, Hiejima H, Mifune H, Sato T, Kangawa K & Kojima M. Developmental changes in the pattern of ghrelin's acyl modification and the levels of acyl-modified ghrelins in murine stomach. Endocrinology 2005 146 2709-2715. (doi:10.1210/en.2004- 0645)
6. Yang J, Brown MS, Liang G, Grishin NV & Goldstein JL. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 2008 132 387-396. (doi:10.1016/j.cell.2008.01.017)
7. Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE & Hale JE. Ghrelin octanoylation mediated by an orphan lipid transferase. PNAS 2008 105 6320-6325. (doi:10.1073/pnas.0800708105)
8. Rinaldo P, Matern D & Bennett MJ. Fatty acid oxidation disorders. Annual Review of Physiology 2002 64 477-502. (doi:10.1146/ annurev.physiol.64. 082201.154705)
9. Shekhawat PS, Matern D & Strauss AW. Fetal fatty acid oxidation disorders, their effect on maternal health and neonatal outcome: impact of expanded newborn screening on their diagnosis and management. Pediatric Research 2005 57 78R-86R. (doi:10. 1203/01.PDR.0000159631.63843.3E)
10. Rinaldo P. Fatty acid transport and mitochondrial oxidation disorders. Seminars in Liver Disease 2001 21 489-500. (doi:10. 1055/s-2001-19037)
11. Rhead WJ. Newborn screening for medium-chain acyl-CoA dehydrogenase deficiency: a global perspective. Journal of Inherited Metabolic Disease 2006 29 370-377. (doi:10.1007/s10545-006- 0292-1)
12. Yasuno T, Kaneoka H, Tokuyasu T, Aoki J, Yoshida S, Takayanagi M, Ohtake A, Kanazawa M, Ogawa A, Tojo K & Saito T. Mutations of carnitine palmitoyltransferase II (CPT II) in Japanese patients with CPT II deficiency. Clinical Genetics 2008 73 496-501. (doi:10.1111/j.1399-0004.2008.00986.x)
13. Akamizu T, Shinomiya T, Irako T, Fukunaga M, Nakai Y & Kangawa K. Separate measurement of plasma levels of acylated and desacyl ghrelin in healthy subjects using a new direct ELISA assay. Journal of Clinical Endocrinology and Metabolism 2005 90 6-9. (doi:10.1210/jc.2004-1640)
14. Date Y, Kojima M, Hosoda H, Sawaguchi A, Mondal MS, Suganuma T, Matsukura S, Kangawa K & Nakazato M. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000 141 4255-4261. (doi:10. 1210/en.141.11.4255)
15. Hosoda H, Kojima M, Matsuo H & Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochemical and Biophysical Research Communications 2000 279 909-913. (doi:10.1006/bbrc.2000.4039)
16. Nishi Y, Hiejima H, Hosoda H, Kaiya H, Mori K, Fukue Y, Yanase T, Nawata H, Kangawa K & Kojima M. Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology 2005 146 2255-2264. (doi:10.1210/en.2004-0695)
17. Shigematsu Y, Hirano S, Hata I, Tanaka Y, Sudo M, Sakura N, Tajima T & Yamaguchi S. Newborn mass screening and selective screening using electrospray tandem mass spectrometry in Japan. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2002 776 39-48. (doi:10.1016/ S1570-0232(02)00077-6)
18. Shigematsu Y, Hata I & Tanaka Y. Stable-isotope dilution measurement of isovalerylglycine by tandem mass spectrometry in newborn screening for isovaleric acidemia. Clinica Chimica Acta 2007 386 82-86. (doi:10.1016/j.cca. 2007.08.003)
19. Ohgusu H, Shirouzu K, Nakamura Y, Nakashima Y, Ida T, Sato T & Kojima M. Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. Biochemical and Biophysical Research Communications 2009 386 153-158. (doi:10.1016/j.bbrc.2009.06.001)
20. Akamizu T, Murayama T, Teramukai S, Miura K, Bando I, Irako T, Iwakura H, Ariyasu H, Hosoda H, Tada H, Matsuyama A, Kojima S, Wada T, Wakatsuki Y, Matsubayashi K, Kawakita T, Shimizu A, Fukushima M, Yokode M & Kangawa K. Plasma ghrelin levels in healthy elderly volunteers: the levels of acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure. Journal of Endocrinology 2006 188 333-344. (doi:10.1677/joe.1.06442)
21. Rigamonti AE, Pincelli AI, Corra B, Viarengo R, Bonomo SM, Galimberti D, Scacchi M, Scarpini E, Cavagnini F & Muller EE. Plasma ghrelin concentrations in elderly subjects: comparison with anorexic and obese patients. Journal of Endocrinology 2002 175 R1-R5. (doi:10.1677/joe.0.175R001)
22. Ikezaki A, Hosoda H, Ito K, Iwama S, Miura N, Matsuoka H, Kondo C, Kojima M, Kangawa K & Sugihara S. Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents. Diabetes 2002 51 3408-3411. (doi:10.2337/diabetes.51. 12. 3408)
23. Inokuchi M, Hasegawa T, Anzo M & Matsuo N. Standardized centile curves of body mass index for Japanese children and adolescents based on the 1978-1981 national survey data. Annals of Human Biology 2006 33 444-453. (doi:10.1080/ 03014460600802353)
24. Kirchner H, Gutierrez JA, Solenberg PJ, Pfluger PT, Czyzyk TA, Willency JA, Schurmann A, Joost HG, Jandacek RJ, Hale JE, Heiman ML & Tschop MH. GOAT links dietary lipids with the endocrine control of energy balance. Nature Medicine 2009 15 741-745. (doi:10.1038/nm.1997)
25. Gempel K, Kiechl S, Hofmann S, Lochmuller H, Kiechl- Kohlendorfer U, Willeit J, Sperl W, Rettinger A, Bieger I, Pongratz D, Gerbitz KD & Bauer MF. Screening for carnitine palmitoyltransferase II deficiency by tandem mass spectrometry. Journal of Inherited Metabolic Disease 2002 25 17-27. (doi:10. 1023/A:1015109127986)
26. Nass R, Farhy LS, Liu J, Prudom CE, Johnson ML, Veldhuis P, Pezzoli SS, Oliveri MC, Gaylinn BD, Geysen HM & Thorner MO. Evidence for acyl-ghrelin modulation of growth hormone release in the fed state. Journal of Clinical Endocrinology and Metabolism 2008 93 1988-1994. (doi:10.1210/jc.2007-2234)
27. Zizzari P, Halem H, Taylor J, Dong JZ, Datta R, Culler MD, Epelbaum J & Bluet-Pajot MT. Endogenous ghrelin regulates episodic growth hormone (GH) secretion by amplifying GH pulse amplitude: evidence from antagonism of the GH secretagogue-R1a receptor. Endocrinology 2005 146 3836-3842. (doi:10.1210/en. 2005-0212)
28. Sun Y, Ahmed S & Smith RG. Deletion of ghrelin impairs neither growth nor appetite. Molecular and Cellular Biology 2003 23 7973-7981. (doi:10.1128/MCB.23.22.7973-7981.2003)
29. Sun Y, Wang P, Zheng H & Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. PNAS 2004 101 4679- 4684. (doi:10.1073/pnas.0305930101)