TGI-Simulator: A visual tool to support the preclinical phase of the drug discovery process by assessing in silico the effect of an anticancer drug

Computer Methods and Programs in Biomedicine

Volumn 105, Issue 2, 2012, Pages 162-174

  Terranova, Nadia ^a   Magni, Paolo ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Antitumor drug; Java and Matlab integration; Model simulation; Pharmacokinetic pharmacodynamic models; Tumor Growth Inhibition model

Indexed keywords

ANTICANCER DRUG; ANTITUMOR DRUGS; DIFFERENTIAL EQUATION SOLVERS; DRUG DEVELOPMENT; DRUG DISCOVERY PROCESS; GRAPHICAL ANIMATION; IN-SILICO; JAVA AND MATLAB INTEGRATION; JAVA GRAPHICAL USER INTERFACE; MODEL IDENTIFICATION; MODEL SIMULATION; OPTIMIZATION ALGORITHMS; PHARMA COMPANIES; POTENTIAL APPLICATIONS; PRECLINICAL STUDIES; SCIENTIFIC CALCULATIONS; SCIENTIFIC SOFTWARES; SELF-INSTALLING; SOFTWARE TOOL; TIME EFFECT; TUMOR GROWTH; TUMOR MASS; VISUAL TOOLS; WEIGHTED LEAST SQUARES;

ALGORITHMS; ANIMATION; COMPUTER SIMULATION; COMPUTER SOFTWARE; DIFFERENTIAL EQUATIONS; GRAPHICAL USER INTERFACES; INDUSTRY; JAVA PROGRAMMING LANGUAGE; MATLAB; PHARMACOKINETICS; TUMORS;

MATHEMATICAL MODELS;

ANTINEOPLASTIC AGENT;

ALGORITHM; ARTICLE; CALCULATION; CANCER INHIBITION; COMPUTER INTERFACE; COMPUTER MODEL; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG EFFECT; MATHEMATICAL MODEL; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; COMPUTER GRAPHICS; COMPUTER SIMULATION; DRUG DISCOVERY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEAST-SQUARES ANALYSIS; MODELS, BIOLOGICAL; NEOPLASMS; SOFTWARE; USER-COMPUTER INTERFACE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84856090378     PISSN: 01692607     EISSN: 18727565     Source Type: Journal    
DOI: 10.1016/j.cmpb.2011.09.001     Document Type: Article

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