Transmyocardial drilling revascularization combined with heparinized bFGF-incorporating stent activates resident cardiac stem cells via SDF-1/CXCR4 axis

Experimental Cell Research

Volumn 318, Issue 4, 2012, Pages 391-399

  Zhang, Guang Wei ^a   Wen, Ti ^b   Gu, Tian Xiang ^a   Li Ling, Jesse ^a,c   Wang, Chun ^a   Zhao, Ye ^a   Liu, Jing ^a   Wang, Ying ^a   Liu, Tian Jun ^d   Lü, Feng ^d  

^a CHINA MEDICAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

^d INSTITUTE OF BIOMEDICAL ENGINEERING   (China)

Author keywords

Coronary artery disease; Fibroblast growth factor 2; Myocardium; Regeneration; Stents

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; STROMAL CELL DERIVED FACTOR 1ALPHA;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL DIAMETER; CARDIAC STEM CELL; CELL ACTIVATION; CELL DIFFERENTIATION; CELL VIABILITY; CLINICAL EFFECTIVENESS; CLINICAL FEATURE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; GENE EXPRESSION REGULATION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HISTOPATHOLOGY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MINIPIG; MUSCLE REGENERATION; MYOCARDIUM REGENERATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVASCULARIZATION; STEM CELL; STENT; TRANSMYOCARDIAL DRILLING REVASCULARIZATION; TREATMENT RESPONSE;

ANIMALIA;

EID: 84856089327     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.11.009     Document Type: Article

References (36)

1. Bergmann O., Bhardwaj R.D., Bernard S., Zdunek S., Barnabé-Heider F., Walsh S., Zupicich J., Alkass K., Buchholz B.A., Druid H., Jovinge S., Frisén J. Evidence for cardiomyocyte renewal in humans. Science 2009, 324:98-102.
2. Kühn B., del Monte F., Hajjar R.J., Chang Y.S., Lebeche D., Arab S., Keating M.T. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat. Med. 2007, 13:962-969.
3. Jopling C., Sleep E., Raya M., Martí M., Raya A., Belmonte J.C. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 2010, 464:606-609.
4. Popescu L.M., Gherghiceanu M., Manole C.G., Faussone-Pellegrini M.S. Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches. J. Cell. Mol. Med. 2009, 13:866-886.
5. Stastna M., Abraham M.R., Van Eyk J.E. Cardiac stem/progenitor cells, secreted proteins, and proteomics. FEBS Lett. 2009, 583:1800-1807.
6. Liu X.C., Zhao J., Wang Y., Liu T.J., Lü F., He G.W. Heparin- and basic fibroblast growth factor- incorporated stent: a new promising method for myocardial revascularization. J. Surg. Res. 2010, 164:204-213.
7. Wang Y., Liu X.C., Zhang G.W., Zhao J., Zhang J.M., Shi R.F., Huang Y.Z., Zhao C.H., Liu T.J., Song C.X., Lü F., Yang Q., He G.W. A new transmyocardial degradable stent combined with growth factor, heparin, and stem cells in acute myocardial infarction. Cardiovasc. Res. 2009, 84:461-469.
8. Zhang G.W., Liu X.C., Li-Ling J., Luan Y., Ying Y.N., Wu X.S., Zhao C.H., Liu T.J., Lü F. Mechanisms of the protective effects of BMSCs promoted by TMDR with heparinized bFGF-incorporated stent in pig model of acute myocardial ischemia. J. Cell. Mol. Med. 2011, 15:1075-1086.
9. Klopsch C., Furlani D., Gäbel R., Li W., Pittermann E., Ugurlucan M., Kundt G., Zingler C., Titze U., Wang W., Ong L.L., Wagner K., Li R.K., Ma N., Steinhoff G. Intracardiac injection of erythropoietin induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model. J. Cell. Mol. Med. 2009, 13:664-679.
10. Wu Q., Shao H., Darwin E.D., Li J., Li J., Yang B., Webster K.A., Yu H. Extracellular calcium increases CXCR4 expression on bone marrow-derived cells and enhances pro-angiogenesis therapy. J. Cell. Mol. Med. 2009, 13:3764-3773.
11. Zhang Y.H., Zhang G.W., Gu T.X., Li-Ling J., Wen T., Zhao Y., Wang C., Fang Q., Yu L., Liu B. Exogenous basic fibroblast growth factor promotes cardiac stem cell mediated myocardial regeneration after miniswine acute myocardial infarction. Coron. Artery Dis. 2011, 22:279-285.
12. Guerrero M., Athota K., Moy J., Mehta L.S., Laguens R., Crottogini A., Borrelli M., Corry P., Schoenherr D., Gentry R., Boura J., Grines C.L., Raff G.L., Shanley C.J., O'Neill W.W. Vascular endothelial growth factor-165 gene therapy promotes cardiomyogenesis in reperfused myocardial infarction. J. Interv. Cardiol. 2008, 21:242-251.
13. Bisi G., Sciagrà R., Santoro G.M., Rossi V., Fazzini P.F. Technetium-99m-sestamibi imaging with nitrate infusion to detect viable hibernating myocardium and predict postrevascularization recovery. J. Nucl. Med. 1995, 36:1994-2000.
14. Djaballah W., Muller M.A., Angioï M., Moulin F., Codreanu A., Mandry D., Ethevenot G., Karcher G., Aliot E., Marie P.Y. Nitrate-enhanced gated SPECT in patients with primary angioplasty for acute myocardial infarction: evidence of a reversible and nitrate-sensitive impairment of myocardial perfusion. Eur. J. Nucl. Med. Mol. Imaging 2007, 34:1981-1990.
15. Spadafora M., Varrella P., Acampa W., Spirito M., Nappi C., Mansi L., Miletto P., Rosato G., Cuocolo A. Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction. Eur. J. Nucl. Med. Mol. Imaging 2010, 37:1730-1735.
16. Flotats A., Carrió I., Estorch M., Bernà L., Catafau A.M., Marí C., Ballester M. Nitrate administration to enhance the detection of myocardial viability by technetium-99m tetrofosmin single-photon emission tomography. Eur. J. Nucl. Med. 1997, 24:767-773.
17. Linke A., Müller P., Nurzynska D., Casarsa C., Torella D., Nascimbene A., Castaldo C., Cascapera S., Böhm M., Quaini F., Urbanek K., Leri A., Hintze T.H., Kajstura J., Anversa P. Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:8966-8971.
18. Urbanek K., Cesselli D., Rota M., Nascimbene A., De Angelis A., Hosoda T., Bearzi C., Boni A., Bolli R., Kajstura J., Anversa P., Leri A. Stem cell niches in the adult mouse heart. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:9226-9231.
19. Smith R.R., Barile L., Cho H.C., Leppo M.K., Hare J.M., Messina E., Giacomello A., Abraham M.R., Marban E. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 2007, 115:896-908.
20. Urbanek K., Rota M., Cascapera S., Bearzi C., Nascimbene A., De Angelis A., Hosoda T., Chimenti S., Baker M., Limana F., Nurzynska D., Torella D., Rotatori F., Rastaldo R., Musso E., Quaini F., Leri A., Kajstura J., Anversa P. Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ. Res. 2005, 97:663-673.
21. Hsieh P.C., Segers V.F., Davis M.E., MacGillivray C., Gannon J., Molkentin J.D., Robbins J., Lee R.T. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat. Med. 2007, 13:970-974.
22. Muraski J.A., Rota M., Misao Y., Fransioli J., Cottage C., Gude N., Esposito G., Delucchi F., Arcarese M., Alvarez R., Siddiqi S., Emmanuel G.N., Wu W., Fischer K., Martindale J.J., Glembotski C.C., Leri A., Kajstura J., Magnuson N., Berns A., Beretta R.M., Houser S.R., Schaefer E.M., Anversa P., Sussman M.A. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat. Med. 2007, 13:1467-1475.
23. Reimer K.A., Lowe J.E., Rasmussen M.M., Jennings R.B. The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs. duration of coronary occlusion in dogs. Circulation 1977, 56:786-794.
24. Tallini Y.N., Greene K.S., Craven M., Spealman A., Breitbach M., Smith J., Fisher P.J., Steffey M., Hesse M., Doran R.M., Woods A., Singh B., Yen A., Fleischmann B.K., Kotlikoff M.I. c-Kit expression identifies cardiovascular precursors in the neonatal heart. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:1808-1813.
25. Wu S.M., Fujiwara Y., Cibulsky S.M., Clapham D.E., Lien C.L., Schultheiss T.M., Orkin S.H. Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 2006, 127:1137-1150.
26. Bearzi C., Rota M., Hosoda T., Tillmanns J., Nascimbene A., De Angelis A., Yasuzawa-Amano S., Trofimova I., Siggins R.W., Lecapitaine N., Cascapera S., Beltrami A.P., D'Alessandro D.A., Zias E., Quaini F., Urbanek K., Michler R.E., Bolli R., Kajstura J., Leri A., Anversa P. Human cardiac stem cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:14068-14073.
27. Hu X., Dai S., Wu W.J., Tan W., Zhu X., Mu J., Guo Y., Bolli R., Rokosh G. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation 2007, 116:654-663.
28. Penn M.S. Importance of the SDF-1:CXCR4 axis in myocardial repair. Circ. Res. 2009, 104:1133-1135.
29. Zakharova L., Mastroeni D., Mutlu N., Molina M., Goldman S., Diethrich E., Gaballa M.A. Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function. Cardiovasc. Res. 2010, 87:40-49.
30. Takehara N., Tsutsumi Y., Tateishi K., Ogata T., Tanaka H., Ueyama T., Takahashi T., Takamatsu T., Fukushima M., Komeda M., Yamagishi M., Yaku H., Tabata Y., Matsubara H., Oh H. Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction. J. Am. Coll. Cardiol. 2008, 52:1858-1865.
31. Rosenblatt-Velin N., Lepore M.G., Cartoni C., Beermann F., Pedrazzini T. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J. Clin. Invest. 2005, 115:1724-1733.
32. Siddiqi S., Gude N., Hosoda T., Muraski J., Rubio M., Emmanuel G., Fransioli J., Vitale S., Parolin C., D'Amario D., Schaefer E., Kajstura J., Leri A., Anversa P., Sussman M.A. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circ. Res. 2008, 103:89-97.
33. Liu X.S., Chopp M., Santra M., Hozeska-Solgot A., Zhang R.L., Wang L., Teng H., Lu M., Zhang Z.G. Functional response to SDF1 alpha through over-expression of CXCR4 on adult subventricular zone progenitor cells. Brain Res. 2008, 1226:18-26.
34. Yoon K.A., Chae Y.M., Cho J.Y. FGF2 stimulates SDF-1 expression through the Erm transcription factor in Sertoli cells. J. Cell. Physiol. 2009, 220:245-256.
35. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS), European Association for Percutaneous Cardiovascular Interventions (EAPCI), Kolh P., Wijns W., Danchin N., Di Mario C., Falk V., Folliguet T., Garg S., Huber K., James S., Knuuti J., Lopez-Sendon J., Marco J., Menicanti L., Ostojic M., Piepoli M.F., Pirlet C., Pomar J.L., Reifart N., Ribichini F.L., Schalij M.J., Sergeant P., Serruys P.W., Silber S., Sousa Uva M., Taggart D. Guidelines on myocardial revascularization. Eur. J. Cardiothorac. Surg. 2010, 38:S1-S52. (Suppl.).
36. Parikh S.V., de Lemos J.A., Jessen M.E., Brilakis E.S., Ohman E.M., Chen A.Y., Wang T.Y., Peterson E.D., Roe M.T., Holper E.M. CRUSADE and ACTION registry-GWTG participants. Timing of in-hospital coronary artery bypass graft surgery for non-ST-segment elevation myocardial infarction patients results from the National Cardiovascular Data Registry ACTION Registry-GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines). JACC Cardiovasc. Interv. 2010, 3:419-427.