Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes

Journal of Investigative Dermatology

Volumn 132, Issue 1, 2012, Pages 246-249

  Jabbari, Ali ^a,b   Suárez Farĩas, Mayte ^b   Dewell, Scott ^b   Krueger, James G ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

DOWN REGULATION; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; KERATINOCYTE; LETTER; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PSORIASIS; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SKIN BIOPSY; TRANSCRIPTOMICS; UPREGULATION;

EID: 84856086455     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.267     Document Type: Letter

References (8)

1. Bowcock AM, Shannon W, Du F et al. (2001) Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum Mol Genet 10:1793-805 (Pubitemid 32899097)
2. Chandran V, Raychaudhuri SP (2010) Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. J Autoimmun 34:J314-21
3. Chiricozzi A, Guttman-Yassky E, Suarez-Farinas M et al. (2011) Integrative responses to IL-17 and TNF-alpha in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis. J Invest Dermatol 131:677-87
4. Gelfand JM, Neimann AL, Shin DB et al. (2006) Risk of myocardial infarction in patients with psoriasis. JAMA 296:1735-41 (Pubitemid 44547793)
5. Gudjonsson JE, Ding J, Li X et al. (2009) Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. J Invest Dermatol 129: 2795-804
6. Jabbari A, Johnson-Huang LM, Krueger JG (2011) Role of the immune system and immunological circuits in psoriasis. G Ital Dermatol Venereol 146:17-30
7. Suarez-Farinas M, Lowes MA, Zaba LC et al. (2010) Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA). PLoS One 5:e10247
8. Zhou X, Krueger JG, Kao MC et al. (2003) Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. Physiol Genomics 13:69-78 (Pubitemid 37129170)