Promotion of hematopoietic differentiation from mouse induced pluripotent stem cells by transient HoxB4 transduction

Stem Cell Research

Volumn 8, Issue 2, 2012, Pages 300-311

  Tashiro, Katsuhisa ^a   Kawabata, Kenji ^a,b   Omori, Miyuki ^a,b   Yamaguchi, Tomoko ^a   Sakurai, Fuminori ^b   Katayama, Kazufumi ^b   Hayakawa, Takao ^c,d   Mizuguchi, Hiroyuki ^a,b  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

^d KINKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD45 ANTIGEN; FIBRINOGEN RECEPTOR; HOX PROTEIN; HOXB4 PROTEIN; STEM CELL ANTIGEN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DIFFERENTIATION; CELL LINE; COLONY FORMATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; FLOW CYTOMETRY; GENETIC TRANSDUCTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; IN VITRO STUDY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSIENT EXPRESSION; TRANSIENT TRANSFECTION; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; ANTIGENS, SURFACE; BIOLOGICAL MARKERS; CELL COUNT; CELL DIFFERENTIATION; COLONY-FORMING UNITS ASSAY; EMBRYOID BODIES; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; IPS;

EID: 84856084977     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2011.09.001     Document Type: Article

References (42)

1. Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., Ito K., Koh G.Y., Suda T. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004, 118:149-161.
2. Bergelson J.M., Cunningham J.A., Droguett G., Kurt-Jones E.A., Krithivas A., Hong J.S., Horwitz M.S., Crowell R.L., Finberg R.W. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 1997, 275:1320-1323.
3. Bowles K.M., Vallier L., Smith J.R., Alexander M.R., Pedersen R.A. HOXB4 overexpression promotes hematopoietic development by human embryonic stem cells. Stem Cells 2006, 24:1359-1369.
4. Carson S.D. Limited proteolysis of the coxsackievirus and adenovirus receptor (CAR) on HeLa cells exposed to trypsin. FEBS Lett. 2000, 484:149-152.
5. Chadwick K., Wang L., Li L., Menendez P., Murdoch B., Rouleau A., Bhatia M. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood 2003, 102:906-915.
6. Evans M.J., Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292:154-156.
7. Godin I., Cumano A. The hare and the tortoise: an embryonic haematopoietic race. Nat. Rev. Immunol. 2002, 2:593-604.
8. Hacein-Bey-Abina S., Von Kalle C., Schmidt M., McCormack M.P., Wulffraat N., Leboulch P., Lim A., Osborne C.S., Pawliuk R., Morillon E., Sorensen R., Forster A., Fraser P., Cohen J.I., de Saint Basile G., Alexander I., Wintergerst U., Frebourg T., Aurias A., Stoppa-Lyonnet D., Romana S., Radford-Weiss I., Gross F., Valensi F., Delabesse E., Macintyre E., Sigaux F., Soulier J., Leiva L.E., Wissler M., Prinz C., Rabbitts T.H., Le Deist F., Fischer A., Cavazzana-Calvo M. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003, 302:415-419.
9. Inamura M., Kawabata K., Takayama K., Tashiro K., Sakurai F., Katayama K., Toyoda M., Akutsu H., Miyagawa Y., Okita H., Kiyokawa N., Umezawa A., Hayakawa T., Furue M.K., Mizuguchi H. Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX. Mol. Ther. 2011, 19:400-407.
10. Kawabata K., Sakurai F., Yamaguchi T., Hayakawa T., Mizuguchi H. Efficient gene transfer into mouse embryonic stem cells with adenovirus vectors. Mol. Ther. 2005, 12:547-554.
11. Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 2005, 19:1129-1155.
12. Kim K., Doi A., Wen B., Ng K., Zhao R., Cahan P., Kim J., Aryee M.J., Ji H., Ehrlich L.I., Yabuuchi A., Takeuchi A., Cunniff K.C., Hongguang H., McKinney-Freeman S., Naveiras O., Yoon T.J., Irizarry R.A., Jung N., Seita J., Hanna J., Murakami P., Jaenisch R., Weissleder R., Orkin S.H., Weissman I.L., Feinberg A.P., Daley G.Q. Epigenetic memory in induced pluripotent stem cells. Nature 2010, 467:285-290.
13. Kulkeaw K., Horio Y., Mizuochi C., Ogawa M., Sugiyama D. Variation in hematopoietic potential of induced pluripotent stem cell lines. Stem Cell Rev. 2010, 6:381-389.
14. Kurita R., Sasaki E., Yokoo T., Hiroyama T., Takasugi K., Imoto H., Izawa K., Dong Y., Hashiguchi T., Soda Y., Maeda T., Suehiro Y., Tanioka Y., Nakazaki Y., Tani K. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells. Stem Cells 2006, 24:2014-2022.
15. Kyba M., Perlingeiro R.C., Daley G.Q. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 2002, 109:29-37.
16. Li Z., Dullmann J., Schiedlmeier B., Schmidt M., von Kalle C., Meyer J., Forster M., Stocking C., Wahlers A., Frank O., Ostertag W., Kuhlcke K., Eckert H.G., Fehse B., Baum C. Murine leukemia induced by retroviral gene marking. Science 2002, 296:497.
17. Maizel J.V., White D.O., Scharff M.D. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology 1968, 36:115-125.
18. Matsumoto K., Isagawa T., Nishimura T., Ogaeri T., Eto K., Miyazaki S., Miyazaki J., Aburatani H., Nakauchi H., Ema H. Stepwise development of hematopoietic stem cells from embryonic stem cells. PLoS One 2009, 4:e4820.
19. McKinney-Freeman S.L., Naveiras O., Yates F., Loewer S., Philitas M., Curran M., Park P.J., Daley G.Q. Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. Blood 2009, 114:268-278.
20. Mikkola H.K., Fujiwara Y., Schlaeger T.M., Traver D., Orkin S.H. Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 2003, 101:508-516.
21. Mitjavila-Garcia M.T., Cailleret M., Godin I., Nogueira M.M., Cohen-Solal K., Schiavon V., Lecluse Y., Le Pesteur F., Lagrue A.H., Vainchenker W. Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development 2002, 129:2003-2013.
22. Mizuguchi H., Kay M.A. Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Hum. Gene Ther. 1998, 9:2577-2583.
23. Mizuguchi H., Kay M.A. A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors. Hum. Gene Ther. 1999, 10:2013-2017.
24. Nakano T., Kodama H., Honjo T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 1994, 265:1098-1101.
25. Niwa H., Yamamura K., Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 1991, 108:193-199.
26. Okabe M., Otsu M., Ahn D.H., Kobayashi T., Morita Y., Wakiyama Y., Onodera M., Eto K., Ema H., Nakauchi H. Definitive proof for direct reprogramming of hematopoietic cells to pluripotency. Blood 2009, 114:1764-1767.
27. Okita K., Ichisaka T., Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007, 448:313-317.
28. Pilat S., Carotta S., Schiedlmeier B., Kamino K., Mairhofer A., Will E., Modlich U., Steinlein P., Ostertag W., Baum C., Beug H., Klump H. HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:12101-12106.
29. Polo J.M., Liu S., Figueroa M.E., Kulalert W., Eminli S., Tan K.Y., Apostolou E., Stadtfeld M., Li Y., Shioda T., Natesan S., Wagers A.J., Melnick A., Evans T., Hochedlinger K. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat. Biotechnol. 2010, 28:848-855.
30. Schiedlmeier B., Santos A.C., Ribeiro A., Moncaut N., Lesinski D., Auer H., Kornacker K., Ostertag W., Baum C., Mallo M., Klump H. HOXB4's road map to stem cell expansion. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:16952-16957.
31. Schmitt T.M., de Pooter R.F., Gronski M.A., Cho S.K., Ohashi P.S., Zuniga-Pflucker J.C. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat. Immunol. 2004, 5:410-417.
32. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
33. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
34. Tashiro K., Kawabata K., Sakurai H., Kurachi S., Sakurai F., Yamanishi K., Mizuguchi H. Efficient adenovirus vector-mediated PPAR gamma gene transfer into mouse embryoid bodies promotes adipocyte differentiation. J. Gene Med. 2008, 10:498-507.
35. Tashiro K., Inamura M., Kawabata K., Sakurai F., Yamanishi K., Hayakawa T., Mizuguchi H. Efficient adipocyte and osteoblast differentiation from mouse induced pluripotent stem cells by adenoviral transduction. Stem Cells 2009, 27:1802-1811.
36. Tashiro K., Kawabata K., Inamura M., Takayama K., Furukawa N., Sakurai F., Katayama K., Hayakawa T., Furue M.K., Mizuguchi H. Adenovirus vector-mediated efficient transduction into human embryonic and induced pluripotent stem cells. Cell. Reprogram. 2010, 12:501-507.
37. Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., Jones J.M. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.
38. Tomko R.P., Xu R., Philipson L. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:3352-3356.
39. Vodyanik M.A., Bork J.A., Thomson J.A., Slukvin I.I. Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood 2005, 105:617-626.
40. Wang Y., Yates F., Naveiras O., Ernst P., Daley G.Q. Embryonic stem cell-derived hematopoietic stem cells. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:19081-19086.
41. Williams D., Baum C. Gene therapy needs both trials and new strategies. Nature 2004, 429:129.
42. Zhang X.B., Beard B.C., Trobridge G.D., Wood B.L., Sale G.E., Sud R., Humphries R.K., Kiem H.P. High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. J. Clin. Invest. 2008, 118:1502-1510.