Minimization of the preanalytical error in plasma samples for pharmacokinetic analyses and therapeutic drug monitoring - Using doxorubicin as an example

Therapeutic Drug Monitoring

Volumn 33, Issue 6, 2011, Pages 766-771

  Kontny, Nina E ^a   Hempel, Georg ^a   Boos, Joachim ^b   Boddy, Alan V ^c   Krischke, Miriam ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Blood sampling; Contamination; Doxorubicin; Pharmacokinetics; Preanalytical error

Indexed keywords

DOXORUBICIN;

ARTICLE; BLOOD SAMPLING; CATHETER; CLINICAL PRACTICE; DRUG BLOOD LEVEL; DRUG CONTAMINATION; DRUG MONITORING; PHARMACOKINETICS; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; BLOOD SPECIMEN COLLECTION; DOXORUBICIN; DRUG MONITORING; GREAT BRITAIN; HUMANS; REPRODUCIBILITY OF RESULTS;

EID: 84856082121     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e31823aa8ab     Document Type: Article

References (27)

1. Bachmann MB, Biscoping J, Adams HA, et al. The significance of the sampling site in the determination of plasma levels of local anesthetics using 0.75% bupivacaine as an example. Reg Anaesth. 1990;13:16-20. (Pubitemid 20088037)
2. Palm C, Bjork O, Bjorkholm M, et al. Quantification of doxorubicin in plasma-a comparative study of capillary and venous blood sampling. Anticancer Drugs. 2001;12:859-864. (Pubitemid 33151536)
3. Shulman RJ, Ou C, Reed T, et al. Central venous catheters versus peripheral veins for sampling blood levels of commonly used drugs. J Parenter Enteral Nutr. 1998;22:234-237. (Pubitemid 28307587)
4. Huitema AD, Holtkamp M, Tibben MM, et al. Sampling technique from central venous catheters proves critical for pharmacokinetic studies. Ther Drug Monit. 1999;21:102-104. (Pubitemid 29077462)
5. Leson CL, Bryson SM, Giesbrecht EE, et al. Therapeutic monitoring of cyclosporine following pediatric bone marrow transplantation: problems with sampling from silicone central venous lines. DICP. 1989;23:300-303. (Pubitemid 19102682)
6. Shader RI, Greenblatt DJ. It's in the bag: drug absorption by drug-delivery systems. J Clin Psychopharmacol. 1997;17:339-340. (Pubitemid 27414387)
7. European Medicines Agency. Guideline on the Investigation of Medicinal Products in the Term and Preterm Neonate. 2007. Available at: http://www.ema.europa.eu/docs/en-GB/document-library/Scientific-guideline/2009/ 09/WC500003754.pdf. Accessed June 27, 2011.
8. European Medicines Agency. Ethical Considerations for Clinical Trials on Medicinal Products Conducted with the Paediatric Population. 2008. Available at: ftp://ftp.cordis.europa.eu/pub/fp7/docs/ethical-considerationspaediatrics-en. pdf. Accessed June 27, 2011.
9. Barton SJ, Chase T, Latham B, et al. Comparing two methods to obtain blood specimens from pediatric central venous catheters. J Pediatr Oncol Nurs. 2004;21:320-326. (Pubitemid 39486328)
10. MacGeorte L, Steeves L, Steeves RH. Comparison of the mixing and reinfusion methods of drawing blood from a Hickman catheter. Oncol Nurs Forum. 1988;15:335-338.
11. Wanwimolruk S, Murphy JE. Effect of monitoring drug concentrations through lines used to administer the drugs: an in vitro study. Ther Drug Monit. 1991;13:443-447.
12. Cole M, Price L, Parry A, et al. A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer. Pediatr Blood Cancer. 2007;48:687-695. (Pubitemid 46717616)
13. Odum L, Drenck NE. Blood sampling for biochemical analysis from central venous catheters: minimizing the volume of discarded blood. Clin Chem Lab Med. 2002;40:152-155. (Pubitemid 34257829)
14. Piazza E, Broggini M, Trabattoni A, et al. Adriamycin distribution in plasma and blood cells of cancer patients with altered hematocrit. Eur J Cancer Clin Oncol. 1981;17:1089-1096. (Pubitemid 11030521)
15. Tomlinson E, Malspeis L. Concomitant adsorption and stability of some anthracycline antibiotics. J Pharm Sci. 1982;71:1121-1125. (Pubitemid 12032676)
16. Hempel G, Schulze-Westhoff P, Flege S, et al. Therapeutic drug monitoring of doxorubicin in paediatric oncology using capillary electrophoresis. Electrophoresis. 1998;19:2939-2943. (Pubitemid 28559922)
17. Maudens KE, Stove CP, Cocquyt VF, et al. Development and validation of a liquid chromatographic method for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites in plasma and saliva. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877:3907-3915.
18. Cash M, Schafhauser B, Byers JF. Venipuncture versus central venous access: a comparison of methotrexate levels in pediatric leukemia patients. J Pediatr Oncol Nurs. 1999;16:189-193.
19. Ritzmo C, Albertioni F, Cosic K, et al. Therapeutic drug monitoring of methotrexate on the pediatric oncology ward: can blood sampling from central venous accesses substitute for capillary finger punctures? Ther Drug Monit. 2007;29:447-451. (Pubitemid 47220462)
20. Ponto LL, Graham MM, Richmond JC, et al. Contamination levels in blood samples drawn from the injection intravenous line. Mol Imaging Bio. 2002;4:410-414. (Pubitemid 36221808)
21. Murphy JE, Ward ES. Elevated phenytoin concentration caused by sampling through the drug-administration catheter. Pharmacotherapy. 1991;11:348-350.
22. Grouzmann E, Buclin T, Biollaz J. Misleading tacrolimus concentration value in blood taken from a catheter used for tacrolimus administration. Am J Health Syst Pharm. 2008;65:226-228. (Pubitemid 351220772)
23. Mogayzel PJ, Pierce E, Mills J, et al. Accuracy of tobramycin levels obtained from central venous access devices in patients with cystic fibrosis is technique dependent. Pediatr Nurs. 2008;34:464-468; quiz 468-469.
24. Wright DF, Al-Sallami HS, Jackson PM, et al. Falsely elevated vancomycin plasma concentrations sampled from central venous implantable catheters (portacaths). Br J Clin Pharmacol. 2010;70:769-772.
25. McBeth CL, McDonald RJ, Hodge MB. Antibiotic sampling from central venous catheters versus peripheral veins. Pediatr Nurs. 2004;30:200-202.
26. Boodhan S, Maloney AM, Dupuis LL. Extent of agreement in gentamicin concentration between serum that is drawn peripherally and from central venous catheters. Pediatrics. 2006;118:1650-1656.
27. Skolnik JM, Zhang AY, Barrett JS. Approaches to clear residual chemotherapeutics from indwelling catheters in children with cancer. Ther Drug Monit. 2010;32:741-748.