-
1
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L et al (2004) BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64:7099-7109
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
3
-
-
38149117040
-
Pneumatosis intestinalis: A variant of bevacizumab related perforation possibly associated with chemotherapy related GI toxicity
-
Asmis TR, Chung KY, Teitcher JB, Kelsen DP, Shah MA (2008) Pneumatosis intestinalis: a variant of bevacizumab related perforation possibly associated with chemotherapy related GI toxicity. Invest New Drugs 26:95-96
-
(2008)
Invest New Drugs
, vol.26
, pp. 95-96
-
-
Asmis, T.R.1
Chung, K.Y.2
Teitcher, J.B.3
Kelsen, D.P.4
Shah, M.A.5
-
5
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
Faivre S, Delbaldo C, Vera K et al (2006) Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 24:25-35
-
(2006)
J Clin Oncol
, vol.24
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
-
6
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
Strumberg D, Richly H, Hilger RA et al (2005) Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 23:965-972
-
(2005)
J Clin Oncol
, vol.23
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
-
7
-
-
77953354537
-
Reversibility of capillary density after discontinuation of bevacizumab treatment
-
Steeghs N, Rabelink TJ, Op't Roodt J, et al (2009) Reversibility of capillary density after discontinuation of bevacizumab treatment. Ann Oncol
-
(2009)
Ann Oncol
-
-
Steeghs, N.1
Rabelink, T.J.2
Op't Roodt, J.3
-
8
-
-
34249894171
-
Gastrointestinal perforation due to bevacizumab in colorectal cancer
-
Saif MW, Elfiky A, Salem RR (2007) Gastrointestinal perforation due to bevacizumab in colorectal cancer. Ann Surg Oncol 14:1860-1869
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 1860-1869
-
-
Saif, M.W.1
Elfiky, A.2
Salem, R.R.3
-
9
-
-
33645362726
-
Increased risk of ischemic bowel complications during treatment with bevacizumab after pelvic irradiation: Report of three cases
-
Lordick F, Geinitz H, Theisen J, Sendler A, Sarbia M (2006) Increased risk of ischemic bowel complications during treatment with bevacizumab after pelvic irradiation: report of three cases. Int J Radiat Oncol Biol Phys 64:1295-1298
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.64
, pp. 1295-1298
-
-
Lordick, F.1
Geinitz, H.2
Theisen, J.3
Sendler, A.4
Sarbia, M.5
-
10
-
-
34548582184
-
Pneumatosis intestinalis in adults: Management, surgical indications, and risk factors for mortality
-
Greenstein AJ, Nguyen SQ, Berlin A et al (2007) Pneumatosis intestinalis in adults: management, surgical indications, and risk factors for mortality. J Gastrointest Surg 11:1268-1274
-
(2007)
J Gastrointest Surg
, vol.11
, pp. 1268-1274
-
-
Greenstein, A.J.1
Nguyen, S.Q.2
Berlin, A.3
-
12
-
-
34249883316
-
Pneumatosis intestinalis in the adult: Benign to life-threatening causes
-
Ho LM, Paulson EK, Thompson WM (2007) Pneumatosis intestinalis in the adult: benign to life-threatening causes. Ajr 188:1604-1613
-
(2007)
Ajr
, vol.188
, pp. 1604-1613
-
-
Ho, L.M.1
Paulson, E.K.2
Thompson, W.M.3
-
13
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain RK (2001) Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 7:987-989
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
14
-
-
33846998337
-
Bevacizumabinduced cardiovascular events: A consequence of cholesterol emboli syndrome?
-
Mir O, Mouthon L, Alexandre J et al (2007) Bevacizumabinduced cardiovascular events: a consequence of cholesterol emboli syndrome? J Natl Cancer Inst 99:85-86
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 85-86
-
-
Mir, O.1
Mouthon, L.2
Alexandre, J.3
-
15
-
-
42649121962
-
Drug insight: Gastrointestinal and hepatic adverse effects of molecular-targeted agents in cancer therapy
-
Loriot Y, Perlemuter G, Malka D et al (2008) Drug insight: gastrointestinal and hepatic adverse effects of molecular-targeted agents in cancer therapy. Nat Clinical Practice 5:268-278
-
(2008)
Nat Clinical Practice
, vol.5
, pp. 268-278
-
-
Loriot, Y.1
Perlemuter, G.2
Malka, D.3
-
16
-
-
66149121478
-
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
-
Hapani S, Chu D, Wu S (2009) Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol 10:559-568
-
(2009)
Lancet Oncol
, vol.10
, pp. 559-568
-
-
Hapani, S.1
Chu, D.2
Wu, S.3
-
17
-
-
62749196646
-
Colonic pneumatosis and intestinal perforations with sunitinib treatment for renal cell carcinoma
-
Flaig TW, Kim FJ, La Rosa FG et al (2009) Colonic pneumatosis and intestinal perforations with sunitinib treatment for renal cell carcinoma. Invest New Drugs 27:83-87
-
(2009)
Invest New Drugs
, vol.27
, pp. 83-87
-
-
Flaig, T.W.1
Kim, F.J.2
La Rosa, F.G.3
-
18
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
Mancuso MR, Davis R, Norberg SM et al (2006) Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 116:2610-2621
-
(2006)
J Clin Invest
, vol.116
, pp. 2610-2621
-
-
Mancuso, M.R.1
Davis, R.2
Norberg, S.M.3
-
19
-
-
50849089255
-
Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery
-
Cacheux W, Boisserie T, Staudacher L et al (2008) Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery. Ann Oncol 19:1659-1661
-
(2008)
Ann Oncol
, vol.19
, pp. 1659-1661
-
-
Cacheux, W.1
Boisserie, T.2
Staudacher, L.3
-
20
-
-
0019799332
-
A method for estimating the probability of adverse drug reactions
-
Naranjo CA, Busto U, Sellers EM et al (1981) A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30:239-245
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 239-245
-
-
Naranjo, C.A.1
Busto, U.2
Sellers, E.M.3
|