Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: A multicenter study of clinicopathology and magnetic resonance imaging findings

International Journal of Gynecological Cancer

Volumn 21, Issue 7, 2011, Pages 1287-1296

  Takatsu, Akiko ^a   Shiozawa, Tanri ^a   Miyamoto, Tsutomu ^a   Kurosawa, Kazuko ^a   Kashima, Hiroyasu ^a   Yamada, Tomoko ^a   Kaku, Tsunehisa ^b   Mikami, Yoshiki ^c   Kiyokawa, Takako ^d   Tsuda, Hitoshi ^e   Ishii, Keiko ^f   Togashi, Kaori ^g   Koyama, Takashi ^h   Fujinaga, Yasunari ⁱ   Kadoya, Masumi ⁱ   Hashi, Akihiko ^j   Susumu, Nobuyuki ^k   Konishi, Ikuo ^l  

^a SHINSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d CHIBA UNIVERSITY   (Japan)

^e NATIONAL CANCER CENTER HOSPITAL   (Japan)

^f Okaya City Hospital   (Japan)

^g KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^h OSAKA RED CROSS HOSPITAL   (Japan)

ⁱ SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^j UNIVERSITY OF YAMANASHI   (Japan)

^k KEIO UNIVERSITY   (Japan)

^l KYOTO UNIVERSITY   (Japan)

more..

Author keywords

Diagnosis; Gastric type mucin; Lobular endocervical glandular hyperplasia (LEGH); Magnetic resonance imaging; Minimal deviation adenocarcinoma (MDA)

Indexed keywords

STOMACH MUCIN;

ARTICLE; CANCER MORPHOLOGY; CANCER RECURRENCE; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYSTERECTOMY; LOBULAR ENDOCERVICAL GLANDULAR HYPERPLASIA; MAJOR CLINICAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PAPANICOLAOU TEST; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; UTERINE CERVIX CANCER; UTERINE CERVIX CONIZATION; UTERINE CERVIX MINIMAL DEVIATION ADENOCARCINOMA; ADENOCARCINOMA; ADULT; AGED; CLINICAL TRIAL; HYPERPLASIA; MIDDLE AGED; MULTICENTER STUDY; PATHOLOGY; PREOPERATIVE CARE; RETROSPECTIVE STUDY; UTERINE CERVIX; UTERINE CERVIX TUMOR; VAGINA SMEAR;

ADENOCARCINOMA; ADULT; AGED; CERVIX UTERI; DIAGNOSIS, DIFFERENTIAL; FEMALE; GASTRIC MUCINS; HUMANS; HYPERPLASIA; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; PREOPERATIVE CARE; RETROSPECTIVE STUDIES; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 84856074072     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0b013e31821f746c     Document Type: Article

References (26)

1. Wright TC, Ferenczy A, Kurman J. Carcinoma and other tumors of the cervix. In: Kurman RJ, ed. Blaustein's Pathology of the Female Genital Tract. 5th ed. New York: Springer-Verlag; 2002:325-381.
2. Vogelsang PJ, Nguyen G, Honoré LH. Exfoliative cytology of adenoma malignum (minimal deviation adenocarcinoma) of the uterine cervix. Diagn Cytopathol. 1995;13:146-150.
3. Granter SR, Lee KR. Cytologic findings in minimal deviation adenocarcinoma (adenoma malignum) of the cervix. A report of seven cases. Am J Clin Pathol. 1996;105:327-333. (Pubitemid 26077374)
4. Doi T, Yamashita Y, Yasunaga T, et al. Adenoma malignum: MR imaging and pathologic study. Radiology. 1997;204:39-42. (Pubitemid 27281706)
5. Oguri H, Maeda N, Izumiya C, et al. MRI of endocervical glandular disorders: three cases of a deep Nabothian cyst and three cases of a minimal-deviation adenocarcinoma. Magn Reson Imaging. 2004;22:1333-1337. (Pubitemid 39647735)
6. Toki T, Shiozawa T, Hosaka N, et al. Minimal deviation adenocarcinoma of the uterine cervix has abnormal expression of sex steroid receptors, CA125, and gastric mucin. Int J Gynecol Pathol. 1997;16:111-116. (Pubitemid 27231290)
7. Ishii K, Kumagai T, Tozuka M, et al. A new diagnostic method for adenoma malignum and related lesions: latex agglutination test with a new monoclonal antibody, HIK1083. Clin Chim Acta. 2001;312:231-233. (Pubitemid 32913603)
8. Ishii K, Katsuyama T, Ota H, et al. Cytologic and cytochemical features of adenoma malignum of the uterine cervix. Cancer. 1999;87:245-253. (Pubitemid 29503477)
9. Nucci MR, Clement PB, Young RH. Lobular endocervical glandular hyperplasia, not otherwise specified: a clinicopathologic analysis of thirteen cases of a distinctive pseudoneoplastic lesion and comparison with fourteen cases of adenoma malignum. Am J Surg Pathol. 1999;23:886-891. (Pubitemid 29360105)
10. Tsuda H, Mikami Y, Kaku T, et al. Interobserver variation in the diagnosis of adenoma malignum (minimal deviation adenocarcinoma) of the uterine cervix. Pathol Int. 2003;53:440-449. (Pubitemid 37000045)
11. Tsuda H, Mikami Y, Kaku T, et al. Reproducible and clinically meaningful differential diagnosis is possible between lobular endocervical glandular hyperplasia and 'adenoma malignum' based on common histopathological criteria. Pathol Int. 2005;55:412-418. (Pubitemid 41097805)
12. Nishio S, Tsuda H, Fujiyoshi N, et al. Clinicopathological significance of cervical adenocarcinoma associated with lobular endocervical glandular hyperplasia. Pathol Res Pract. 2009;205:331-337.
13. Kondo T, Hashi A, Murata S, et al. Endocervical adenocarcinomas associated with lobular endocervical glandular hyperplasia: a report of four cases with histochemical and immunohistochemical analyses. Mod Pathol. 2005;18:1199-1210. (Pubitemid 43079919)
14. Mikami Y, Hata S, Fujiwara K, et al. Florid endocervical glandular hyperplasia with intestinal and pyloric gland metaplasia: worrisome benign mimic of "adenoma malignum". Gynecol Oncol. 1999;74:504-511. (Pubitemid 29439901)
15. Kawauchi S, Kusuda T, Liu XP, et al. Is lobular endocervical glandular hyperplasia a cancerous precursor of minimal deviation adenocarcinoma?: a comparative molecular-genetic and immunohistochemical study. Am J Surg. 2008;32:1807-1815.
16. Ishii K, Hosaka N, Toki T, et al. A new view of the so-called adenoma malignum of the uterine cervix. Virchows Arch. 1998;432:315-322. (Pubitemid 28171993)
17. Honda T, Ota H, Ishii K, et al. Mucinous bronchioloalveolar carcinoma with organoid differentiation simulating the pyloric mucosa of the stomach: clinicopathologic, histochemical, and immunohistochemical analysis. Am J Clin Pathol. 1998;109:423-430. (Pubitemid 28151030)
18. Kaminski PF, Norris HJ. Minimal deviation carcinoma adenoma malignum) of the cervix. Int J Gynecol Pathol. 1983;2:141-152. (Pubitemid 14235221)
19. Michael H, Grawe L, Kraus FT. Minimal deviation endocervical adenocarcinoma: clinical and histologic features, immunohistochemical staining for carcinoembryonic antigen, and differentiation from confusing benign lesions. Int J Gynecol Pathol. 1984;3:261-276. (Pubitemid 15180381)
20. Omori M, Hashi A, Ishii Y, et al. Clinical impact of preoperative screening for gastric mucin secretion in cervical discharge by HIK1083-labeled latex agglutination test. Am J Clin Pathol. 2008;130:585-594.
21. Mikami Y, Kiyokawa T, Hata S, et al. Gastrointestinal immunophenotype in adenocarcinomas of the uterine cervix and related glandular lesions: a possible link between lobular endocervical glandular hyperplasia/pyloric gland metaplasia and 'adenoma malignum'. Mod Pathol. 2004;17:962-972. (Pubitemid 38993781)
22. Nara M, Hashi A, Murata S, et al. Lobular endocervical glandular hyperplasia as a presumed precursor of cervical adenocarcinoma independent of human papillomavirus infection. Gynecol Oncol. 2007;106:289-298. (Pubitemid 47087929)
23. Hashi A, Xu JY, Kondo T, et al. p16INK4a overexpression independent of human papillomavirus infection in lobular endocervical glandular hyperplasia. Int J Gynecol Pathol. 2006;25:187-194. (Pubitemid 44620184)
24. Yoden E, Mikami Y, Fujiwara K, et al. Florid endocervical glandular hyperplasia with pyloric gland metaplasia: a radiologic pitfall. J Comput Assist Tomogr. 2001;25:94-97. (Pubitemid 32099215)
25. Bardsley M, Pather S, Neesham D, et al. Benign endocervical cystic glandular change mimicking minimal deviation adenocarcinoma of the cervix on magnetic resonance imaging: a case report. Aust N Z J Obstet Gynaecol. 2004;44:358-359. (Pubitemid 39193374)
26. Sugiyama K, Takehara Y. MR findings of pseudoneoplastic lesions in the uterine cervix mimicking adenoma malignum. Br J Radiol. 2007;80:878-883. (Pubitemid 350206216)