Preparation and characterization of gelatin-poly(L-lactic) acid/poly(hydroxybutyrate-co-hydroxyvalerate) composite nanofibrous scaffolds

Journal of Macromolecular Science, Part B: Physics

Volumn 50, Issue 9, 2011, Pages 1705-1713

  Feng, Shuqin ^a   Shen, Xinyuan ^a   Fu, Zhongyu ^b   Shao, Meiling ^a  

^a DONGHUA UNIVERSITY   (China)

^b BEIJING INSTITUTE OF FASHION TECHNOLOGY   (China)

Author keywords

Cell biocompatibility; Electrospinning; Mechanical properties; PLLA; Tissue engineering

Indexed keywords

BIOLOGICAL FIELDS; CELL MORPHOLOGY; COMPOSITE NANOFIBERS; COMPOSITE SCAFFOLDS; DEGRADATION RATE; DEGRADATION TEST; DERMAL FIBROBLASTS; ELECTROSPUNS; HYDROPHOBIC NATURE; IN-VITRO; NANOFIBROUS SCAFFOLDS; PLLA; POLY L LACTIC ACID; SEM IMAGE; SLOW DEGRADATION; TISSUE ENGINEERING SCAFFOLD; WATER CONTACT ANGLE MEASUREMENT;

ADHESION; BIOCOMPATIBILITY; BIOMECHANICS; BROMINE COMPOUNDS; CELL CULTURE; CONTACT ANGLE; DEGRADATION; ELECTROSPINNING; FIBROBLASTS; HYDROPHILICITY; MECHANICAL PROPERTIES; MORPHOLOGY; NANOFIBERS; SCANNING ELECTRON MICROSCOPY; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

EID: 84856072316     PISSN: 00222348     EISSN: 1525609X     Source Type: Journal    
DOI: 10.1080/00222348.2010.541002     Document Type: Article

References (23)

1. Rai, B.; Noohom, W.; Kithva, PH.; Grondahl, L.; Trau, M. Bionanohydroxyapatite/poly(3hydroxybutyrate-co-3-hydroxyvalerate) composites with improved particle dispersion and superior mechanical properties. Chem. Mater. 2008, 20, 2802-2808. (Pubitemid 351655920)
2. Duan, B.; Wang, M.; Zhou, W.Y.; Cheung, W.L. Synthesis of Ca-P nanoparticles and fabrication of Ca-P/PHBV nanocomposite microspheres for bone tissue engineering applications. Appl. Surf. Sci. 2008, 255, 529-533.
3. Zhao, L.; He, C.G.; Gao, Y.J.; Cen, L.; Cui, L.; Cao, Y.L.J. Preparation and cytocompatibility of PLGA scaffolds with controllable fiber morphology and diameter using electrospinning method. Biomed. Mater. Res. Part B-Appl. Biomater. 2008, 87, 26-34.
4. Xu, C.Y; Inai, R.; Kotaki, M.; Ramakrishna, S. Aligned biodegradable nanotibrous structure: A potential scaffold for blood vessel engineering. Biomaterials 2004, 25, 877-886. (Pubitemid 37371995)
5. Li, J.X.; He, A.H.; Han, C.C; Fang, D.F.; Hsiao, B.S.; Chu, B. Electrospinning of hyaluronic acid (HA) and HA/gelatin blends. Macromol. Rapid. Commun. 2006, 27, 114-120.
6. Kim, C.H.; Khil, M.S.; Kim, H.Y; Lee, H.U.; Jahng, K.Y An improved hydrophilicity via electrospinning for enhanced cell attachment and proliferation. J. Biomat. Mater. Res. Part B-Appl. Biomater. 2006, 78, 283-290. (Pubitemid 44167730)
7. Cheng, M. Y; Deng, J.U.; Yang, F.; Gong, Y.D.; Zhao, N.M.; Zhang, X.F. Study on physical properties and nerve cell affinity of composite films from chitosan and gelatin solutions. Biomaterials 2003, 24, 2871-2880.
8. Chong, E.J.; Phan, T.T; Lim, I.J.; Zhang, YZ.; Bay, B.H.; Ramakrishna, S.; Lim, C.T Evaluation of electrospun PCL/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution. Acta Biomater. 2007, 3, 321-330. (Pubitemid 46555131)
9. Schnell, E.; Klinkhammer, K.; Balzer, S.; Brook, G.; Kleeb, D.; Dalton, P; Mey, J. Guidance of glial cell. Migration and axonal growth on electrospun nanofibers of poly-epsilon-caprolactone and a collagen/poly-epsilon-caprolactone blend. Biomaterials 2007, 28, 3012-3025. (Pubitemid 46560871)
10. Wang, S.A.; Ma, P.M.; Wang, R.Y; Wang, S.F.; Zhang, Y; Zhang, Y.X. Mechanical, thermal and degradation properties of poly(d,l-lactide)/ poly(hydroxybutyrate-cohydroxyvalerate)/poly(ethylene glycol) blend. Polym. Degrad. Stab. 2008, 93, 1364-1369.
11. Dai, Z.W.; Zou, X.H.; Chen, G.Q. Poly(3-hydroxybutyrate-co-3- hydroxyhexanoate) as an injectable implant system for prevention of post-surgical tissue adhesion. Biomaterials 2009, 30, 3075-3083.
12. Wang, YJ.; Wang, X.D.; Wei, K. Fabrication, characterization and long-term in vitro release of hydrophilic drug using PHBV/HA composite microspheres. Mater. Lett. 2007, 61, 1071-1076. (Pubitemid 46054271)
13. Wang, Y; Bian, Y.Z.; Wu, Q.; Chen, G.Q. Evaluation of three-dimensional scaffolds prepared from poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for growth of allogeneic chondrocytes for cartilage repair in rabbits. Biomaterials 2008, 29, 2858-2868.
14. Sun, Q.S.; Dong, J.; Lin, Z.X.; Yang, B.; Wang, J.Y Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro. Biopolymers 2005, 78, 268-274. (Pubitemid 41191966)
15. Zhang, L.L.; Xiong, C.D.; Dong, X.M. Miscibility, crystallization and morphology of poly(bhydroxybutyrate)/poly(d,l-lactide) blends. Polymer 1996, 37, 235-241.
16. Nagahama, H.; Maeda, H.; Kashiki, T; Jayakumar, R.; Furuike, T; Tamura, H. Preparation and characterization of novel chitosan/gelatin scaffoldss using chitosan hydrogel. Carbohydr. Polym. 2009, 76, 255-260.
17. Liu, X.H.; Won, Y.J.; Ma, P.X. Porogen-induced surface modification of nano-fibrous poly (Llactic acid) scaffolds for tissue engineering. Biomaterials 2006, 27, 3980-3987. (Pubitemid 44316597)
18. Hu, S.G.; Jou, C.H.; Yang, M.C. Biocompatibility and antibacterial activity of chitosan and collagen immobilized poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid). Carbohydr. Polym. 2004,58, 173-179.
19. Graham, G.J.; Freshney, M.G. CFU-A assay for measurement of the antiproliferative effects of chemokines on murine early hemopoietic progenitors. Methods Molec. Biol. 2008,138,179-189.
20. Correio, V.M.; Pinho, E.D.; Pashkuleva, L; Bhattacharya, M.; Neves, N.M.; Reis, R.L. Water absorption and degradation characteristics of chitosan-based polyesters and hydroxyapatite composites. Macromol. Biosci. 2007, 7, 354-363. (Pubitemid 47264656)
21. Li, W.J.; Cooper, J.; Mauck, R.L.; Tuan, R.S. Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications. Acta. Biomater. 2006, 2, 377-385. (Pubitemid 43840927)
22. Koh, H.S.; Yong, T; Chan, C.K.; Ramakrishna, S. Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin. Biomaterials 2008, 29, 3574-3582.
23. Babensee, J.E.; Anderson, J.M.; Mclntire, L.V.; Mikos, A.G. Host response to tissue engineered devices. Adv. Drug. Deliv. Rev. 1998, 33, 111-139. (Pubitemid 28403539)