-
2
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
DOI 10.1038/sj.onc.1208615
-
Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops Oncogene 24 2005 2899 2908 (Pubitemid 40638098)
-
(2005)
Oncogene
, vol.24
, Issue.17
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
3
-
-
33845270990
-
Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
-
DOI 10.1038/nrc2012, PII NRC2012
-
Toledo F., and Wahl G.M. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas Nat. Rev. Cancer 6 2006 909 923 (Pubitemid 44862676)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.12
, pp. 909-923
-
-
Toledo, F.1
Wahl, G.M.2
-
4
-
-
32544442894
-
Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress
-
DOI 10.1038/sj.onc.1209126, PII 1209126
-
Speidel D., Helmbold H., and Deppert W. Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress Oncogene 25 2006 940 953 (Pubitemid 43237712)
-
(2006)
Oncogene
, vol.25
, Issue.6
, pp. 940-953
-
-
Speidel, D.1
Helmbold, H.2
Deppert, W.3
-
5
-
-
50149097809
-
A complex barcode underlies the heterogeneous response of p53 to stress
-
Murray-Zmijewski F., Slee E.A., and Lu X. A complex barcode underlies the heterogeneous response of p53 to stress Nat. Rev. Mol. Cell Biol. 9 2008 702 712
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 702-712
-
-
Murray-Zmijewski, F.1
Slee, E.A.2
Lu, X.3
-
8
-
-
65549120715
-
Modes of p53 regulation
-
Kruse J.P., and Gu W. Modes of p53 regulation Cell 137 2009 609 622
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
9
-
-
0026702212
-
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
-
Zambetti G.P., Bargonetti J., Walker K., Prives C., and Levine A.J. Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element Genes Dev. 6 1992 1143 1152
-
(1992)
Genes Dev.
, vol.6
, pp. 1143-1152
-
-
Zambetti, G.P.1
Bargonetti, J.2
Walker, K.3
Prives, C.4
Levine, A.J.5
-
10
-
-
0034881964
-
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment
-
DOI 10.1016/S1097-2765(01)00283-0
-
Espinosa J.M., and Emerson B.M. Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment Mol. Cell 8 2001 57 69 (Pubitemid 32772905)
-
(2001)
Molecular Cell
, vol.8
, Issue.1
, pp. 57-69
-
-
Espinosa, J.M.1
Emerson, B.M.2
-
11
-
-
34047174813
-
Structural Biology of the Tumor Suppressor p53 and Cancer-Associated Mutants
-
DOI 10.1016/S0065-230X(06)97001-8, PII S0065230X06970018
-
Joerger A.C., and Fersht A.R. Structural biology of the tumor suppressor p53 and cancer-associated mutants Adv. Cancer Res. 97 2007 1 23 (Pubitemid 46528983)
-
(2007)
Advances in Cancer Research
, vol.97
, pp. 1-23
-
-
Joerger, A.C.1
Fersht, A.R.2
-
12
-
-
0027990725
-
P53 domains: Structure, oligomerization, and transformation
-
Wang P., Reed M., Wang Y., Mayr G., Stenger J.E., and Anderson M.E. p53 domains: structure, oligomerization, and transformation Mol. Cell. Biol. 14 1994 5182 5191 (Pubitemid 24235946)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.8
, pp. 5182-5191
-
-
Wang, P.1
Reed, M.2
Wang, Y.3
Mayr, G.4
Stenger, J.E.5
Anderson, M.E.6
Schwedes, J.F.7
Tegtmeyer, P.8
-
13
-
-
0034862475
-
The C-terminus of p53: The more you learn the less you know
-
DOI 10.1038/nsb0901-730
-
Ahn J., and Prives C. The C-terminus of p53: the more you learn the less you know Nat. Struct. Biol. 8 2001 730 732 (Pubitemid 32803581)
-
(2001)
Nature Structural Biology
, vol.8
, Issue.9
, pp. 730-732
-
-
Ahn, J.1
Prives, C.2
-
14
-
-
0026448672
-
Regulation of the specific DNA binding function of p53
-
Hupp T.R., Meek D.W., Midgley C.A., and Lane D.P. Regulation of the specific DNA binding function of p53 Cell 71 1992 875 886
-
(1992)
Cell
, vol.71
, pp. 875-886
-
-
Hupp, T.R.1
Meek, D.W.2
Midgley, C.A.3
Lane, D.P.4
-
15
-
-
0029124132
-
Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53
-
Abarzua P., LoSardo J.E., Gubler M.L., and Neri A. Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53 Cancer Res. 55 1995 3490 3494
-
(1995)
Cancer Res.
, vol.55
, pp. 3490-3494
-
-
Abarzua, P.1
Losardo, J.E.2
Gubler, M.L.3
Neri, A.4
-
16
-
-
0028845158
-
Small peptides activate the latent sequence-specific DNA binding function of p53
-
Hupp T.R., Sparks A., and Lane D.P. Small peptides activate the latent sequence-specific DNA binding function of p53 Cell 83 1995 237 245
-
(1995)
Cell
, vol.83
, pp. 237-245
-
-
Hupp, T.R.1
Sparks, A.2
Lane, D.P.3
-
17
-
-
0030961889
-
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
-
DOI 10.1038/nm0697-632
-
Selivanova G., Iotsova V., Okan I., Fritsche M., Strom M., and Groner B. Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain Nat. Med. 3 1997 632 638 (Pubitemid 27264972)
-
(1997)
Nature Medicine
, vol.3
, Issue.6
, pp. 632-638
-
-
Selivanova, G.1
Iotsova, V.2
Okan, I.3
Fritsche, M.4
Strom, M.5
Groner, B.6
Grafstrom, R.C.7
Wiman, K.G.8
-
18
-
-
0032911047
-
Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain
-
Selivanova G., Ryabchenko L., Jansson E., Iotsova V., and Wiman K.G. Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain Mol. Cell. Biol. 19 1999 3395 3402 (Pubitemid 29193799)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3395-3402
-
-
Selivanova, G.1
Ryabchenko, L.2
Jansson, E.3
Iotsova, V.4
Wiman, K.G.5
-
19
-
-
0034869859
-
Latent and active p53 are identical in conformation
-
DOI 10.1038/nsb0901-756
-
Ayed A., Mulder F.A., Yi G.S., Lu Y., Kay L.E., and Arrowsmith C.H. Latent and active p53 are identical in conformation Nat. Struct. Biol. 8 2001 756 760 (Pubitemid 32803591)
-
(2001)
Nature Structural Biology
, vol.8
, Issue.9
, pp. 756-760
-
-
Ayed, A.1
Mulder, F.A.A.2
Yi, G.-S.3
Lu, Y.4
Kay, L.E.5
Arrowsmith, C.H.6
-
20
-
-
0037039319
-
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
-
DOI 10.1073/pnas.012283399
-
Kaeser M.D., and Iggo R.D. Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo Proc. Natl Acad. Sci. USA 99 2002 95 100 (Pubitemid 34060322)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.1
, pp. 95-100
-
-
Kaeser, M.D.1
Iggo, R.D.2
-
21
-
-
0036784608
-
Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein
-
McKinney K., and Prives C. Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein Mol. Cell. Biol. 22 2002 6797 6808
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6797-6808
-
-
McKinney, K.1
Prives, C.2
-
22
-
-
0037174933
-
Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain
-
DOI 10.1074/jbc.M202344200
-
Gohler T., Reimann M., Cherny D., Walter K., Warnecke G., Kim E., and Deppert W. Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain J. Biol. Chem. 277 2002 41192 41203 (Pubitemid 35215711)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 41192-41203
-
-
Gohler, T.1
Reimann, M.2
Cherny, D.3
Walter, K.4
Warnecke, G.5
Kim, E.6
Deppert, W.7
-
23
-
-
79952259642
-
A single-molecule characterization of p53 search on DNA
-
Tafvizi A., Huang F., Fersht A.R., Mirny L.A., and van Oijen A.M. A single-molecule characterization of p53 search on DNA Proc. Natl Acad. Sci. USA 108 2010 563 568
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 563-568
-
-
Tafvizi, A.1
Huang, F.2
Fersht, A.R.3
Mirny, L.A.4
Van Oijen, A.M.5
-
24
-
-
8644241631
-
P53 linear diffusion along DNA requires its C terminus
-
DOI 10.1016/j.molcel.2004.09.032, PII S1097276504005842
-
McKinney K., Mattia M., Gottifredi V., and Prives C. p53 linear diffusion along DNA requires its C terminus Mol. Cell 16 2004 413 424 (Pubitemid 39504795)
-
(2004)
Molecular Cell
, vol.16
, Issue.3
, pp. 413-424
-
-
McKinney, K.1
Mattia, M.2
Gottifredi, V.3
Prives, C.4
-
25
-
-
2942612843
-
Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53
-
DOI 10.1016/j.cell.2004.05.009, PII S0092867404004891
-
An W., Kim J., and Roeder R.G. Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53 Cell 117 2004 735 748 (Pubitemid 38748890)
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 735-748
-
-
An, W.1
Kim, J.2
Roeder, R.G.3
-
26
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
DOI 10.1016/S0092-8674(00)80521-8
-
Gu W., and Roeder R.G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain Cell 90 1997 595 606 (Pubitemid 27357952)
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
27
-
-
0028673142
-
Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases
-
Hupp T.R., and Lane D.P. Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases Cold Spring Harbor Symp. Quant. Biol. 59 1994 195 206
-
(1994)
Cold Spring Harbor Symp. Quant. Biol.
, vol.59
, pp. 195-206
-
-
Hupp, T.R.1
Lane, D.P.2
-
28
-
-
0029055808
-
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
-
Jayaraman J., and Prives C. Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus Cell 81 1995 1021 1029
-
(1995)
Cell
, vol.81
, pp. 1021-1029
-
-
Jayaraman, J.1
Prives, C.2
-
29
-
-
0842282837
-
Reconstitution and Transcriptional Analysis of Chromatin In Vitro
-
DOI 10.1016/S0076-6879(03)77030-X
-
An W., and Roeder R.G. Reconstitution and transcriptional analysis of chromatin in vitro Methods Enzymol. 377 2004 460 474 (Pubitemid 38166835)
-
(2004)
Methods in Enzymology
, vol.377
, pp. 460-474
-
-
An, W.1
Roeder, R.G.2
|