A novel role for α-Tocopherol Transfer Protein (α-TTP) in protecting against chloroquine toxicity

Journal of Biological Chemistry

Volumn 287, Issue 4, 2012, Pages 2926-2934

  Shichiri, Mototada ^a,b,c   Kono, Nozomu ^a   Shimanaka, Yuta ^a   Tanito, Masaki ^d   Rotzoll, Daisy E ^e   Yoshida, Yasukazu ^b   Hagihara, Yoshihisa ^b   Tamai, Hiroshi ^c   Arai, Hiroyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EYE PROTECTION; MAMMALS; PROTEINS;

ANTIMALARIAL AGENT; AUTOIMMUNE DISEASE; CASPASE ACTIVATION; CLINICAL TREATMENTS; OSMOTIC SWELLING; PERMEABILIZATION; TRANSFECTANT CELLS; TRANSFER PROTEIN;

TOXICITY;

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL TRANSFER PROTEIN; BAFILOMYCIN A1; CELL PROTEIN; CHLOROQUINE; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL ORGANELLE; CELL PH; CELL PROTECTION; CELL VACUOLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; GENETIC TRANSFECTION; HEPATOMA CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINOPATHY; VITAMIN SUPPLEMENTATION; WILD TYPE;

MUS; RATTUS;

EID: 84856068485     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.321281     Document Type: Article

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