Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 6, 2005, Pages 947-951

  Michihara, Akihiro ^a   Toda, Ken ^a   Kubo, Takuo ^a   Fujiwara, Yoshiteru ^a   Akasaki, Kenji ^a   Tsuji, Hiroshi ^a  

^a FUKUYAMA UNIVERSITY   (Japan)

Author keywords

glucuronidase; Chloroquine; Cytosol; Lamp 1; Lysosome

Indexed keywords

ANTIMALARIAL AGENT; BETA GLUCURONIDASE; CARBOXYLYASE; CHLOROQUINE; DIGITONIN; DIPHOSPHOMEVALONATE DECARBOXYLASE; GLYCOPROTEIN; LYSOSOMAL MEMBRANE GLYCOPROTEIN 1; LYSOSOME ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DISRUPTION; CELL FRACTIONATION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOSOL; DENSITY GRADIENT CENTRIFUGATION; ENZYME ACTIVITY; LIVER CELL; LYSOSOME; MALE; NONHUMAN; RAT;

ANIMALS; CELLS, CULTURED; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; LYSOSOMES; MALE; RATS; RATS, WISTAR;

EID: 21144452389     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.947     Document Type: Article

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