메뉴 건너뛰기




Volumn 205, Issue 1, 2012, Pages 139-147

Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons

Author keywords

Cell targeting; Motor neurons; Promoters; Viral vectors

Indexed keywords

LENTIVIRUS VECTOR; RECOMBINANT LENTIVIRUS VECTOR; UNCLASSIFIED DRUG;

EID: 84856064875     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.12.024     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 33746932893 scopus 로고    scopus 로고
    • Gene delivery to the spinal cord: comparison between lentiviral, adenoviral, and retroviral vector delivery systems
    • Abdellatif A.A., Pelt J.L., Benton R.L., Howard R.M., Tsoulfas P., Ping P., et al. Gene delivery to the spinal cord: comparison between lentiviral, adenoviral, and retroviral vector delivery systems. J Neurosci Res 2006, 84:553-567.
    • (2006) J Neurosci Res , vol.84 , pp. 553-567
    • Abdellatif, A.A.1    Pelt, J.L.2    Benton, R.L.3    Howard, R.M.4    Tsoulfas, P.5    Ping, P.6
  • 2
    • 20844463069 scopus 로고    scopus 로고
    • Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses
    • Abordo-Adesida E., Follenzi A., Barcia C., Sciascia S., Castro M.G., Naldini L., et al. Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses. Hum Gene Ther 2005, 16:741-751.
    • (2005) Hum Gene Ther , vol.16 , pp. 741-751
    • Abordo-Adesida, E.1    Follenzi, A.2    Barcia, C.3    Sciascia, S.4    Castro, M.G.5    Naldini, L.6
  • 3
    • 0033180516 scopus 로고    scopus 로고
    • Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity
    • Arber S., Han B., Mendelsohn M., Smith M., Jessell T.M., Sockanathan S. Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 1999, 23:659-674.
    • (1999) Neuron , vol.23 , pp. 659-674
    • Arber, S.1    Han, B.2    Mendelsohn, M.3    Smith, M.4    Jessell, T.M.5    Sockanathan, S.6
  • 4
    • 4444225921 scopus 로고    scopus 로고
    • Non-primate EIAV-based lentiviral vectors as gene delivery system for motor neuron diseases
    • Azzouz M., Mazarakis N. Non-primate EIAV-based lentiviral vectors as gene delivery system for motor neuron diseases. Curr Gene Ther 2004, 4:277-286.
    • (2004) Curr Gene Ther , vol.4 , pp. 277-286
    • Azzouz, M.1    Mazarakis, N.2
  • 5
    • 2642526164 scopus 로고    scopus 로고
    • VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
    • Azzouz M., Ralph G.S., Storkebaum E., Walmsley L.E., Mitrophanous K.A., Kingsman S.M., et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004, 429:413-417.
    • (2004) Nature , vol.429 , pp. 413-417
    • Azzouz, M.1    Ralph, G.S.2    Storkebaum, E.3    Walmsley, L.E.4    Mitrophanous, K.A.5    Kingsman, S.M.6
  • 6
    • 2342446492 scopus 로고    scopus 로고
    • Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer
    • Blesch A. Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer. Methods 2004, 33:164-172.
    • (2004) Methods , vol.33 , pp. 164-172
    • Blesch, A.1
  • 7
    • 36849060584 scopus 로고    scopus 로고
    • Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
    • Brown B.D., Gentner B., Cantore A., Colleoni S., Amendola M., Zingale A., et al. Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state. Nat Biotechnol 2007, 25:1457-1467.
    • (2007) Nat Biotechnol , vol.25 , pp. 1457-1467
    • Brown, B.D.1    Gentner, B.2    Cantore, A.3    Colleoni, S.4    Amendola, M.5    Zingale, A.6
  • 8
    • 33646564701 scopus 로고    scopus 로고
    • Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
    • Brown B.D., Venneri M.A., Zingale A., Sergi Sergi L., Naldini L. Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer. Nat Med 2006, 12:585-591.
    • (2006) Nat Med , vol.12 , pp. 585-591
    • Brown, B.D.1    Venneri, M.A.2    Zingale, A.3    Sergi Sergi, L.4    Naldini, L.5
  • 10
    • 79951991424 scopus 로고    scopus 로고
    • Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis
    • Chang Q., Martin L.J. Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci 2011, 31(8):2815-2827.
    • (2011) J Neurosci , vol.31 , Issue.8 , pp. 2815-2827
    • Chang, Q.1    Martin, L.J.2
  • 12
    • 80052435603 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: an update
    • de Carvalho M., Swash M. Amyotrophic lateral sclerosis: an update. Curr Opin Neurol 2011, 24:497-503.
    • (2011) Curr Opin Neurol , vol.24 , pp. 497-503
    • de Carvalho, M.1    Swash, M.2
  • 14
    • 78149251540 scopus 로고    scopus 로고
    • Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS
    • Ezzi S.A., Lariviere R., Urushitani M., Julien J.P. Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS. J Neurochem 2010, 115:1102-1111.
    • (2010) J Neurochem , vol.115 , pp. 1102-1111
    • Ezzi, S.A.1    Lariviere, R.2    Urushitani, M.3    Julien, J.P.4
  • 15
    • 2342614295 scopus 로고    scopus 로고
    • Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice
    • Guillot S., Azzouz M., Deglon N., Zurn A., Aebischer P. Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice. Neurobiol Dis 2004, 16:139-149.
    • (2004) Neurobiol Dis , vol.16 , pp. 139-149
    • Guillot, S.1    Azzouz, M.2    Deglon, N.3    Zurn, A.4    Aebischer, P.5
  • 16
    • 35848967574 scopus 로고    scopus 로고
    • Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells
    • Hendriks W.T., Eggers R., Verhaagen J., Boer G.J. Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells. J Neurosci Res 2007, 85:3041-3052.
    • (2007) J Neurosci Res , vol.85 , pp. 3041-3052
    • Hendriks, W.T.1    Eggers, R.2    Verhaagen, J.3    Boer, G.J.4
  • 17
    • 73449091512 scopus 로고    scopus 로고
    • AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS
    • Hester M.E., Foust K.D., Kaspar R.W., Kaspar B.K. AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS. Curr Gene Ther 2009, 9:428-433.
    • (2009) Curr Gene Ther , vol.9 , pp. 428-433
    • Hester, M.E.1    Foust, K.D.2    Kaspar, R.W.3    Kaspar, B.K.4
  • 18
    • 0034982656 scopus 로고    scopus 로고
    • Neuron-specific expression of Cre recombinase during the late phase of brain development
    • Hirasawa M., Cho A., Sreenath T., Sauer B., Julien J.P., Kulkarni A.B. Neuron-specific expression of Cre recombinase during the late phase of brain development. Neurosci Res 2001, 40:125-132.
    • (2001) Neurosci Res , vol.40 , pp. 125-132
    • Hirasawa, M.1    Cho, A.2    Sreenath, T.3    Sauer, B.4    Julien, J.P.5    Kulkarni, A.B.6
  • 19
    • 39849103473 scopus 로고    scopus 로고
    • Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
    • Jaarsma D., Teuling E., Haasdijk E.D., De Zeeuw C.I., Hoogenraad C.C. Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J Neurosci 2008, 28:2075-2088.
    • (2008) J Neurosci , vol.28 , pp. 2075-2088
    • Jaarsma, D.1    Teuling, E.2    Haasdijk, E.D.3    De Zeeuw, C.I.4    Hoogenraad, C.C.5
  • 21
    • 33744820829 scopus 로고    scopus 로고
    • Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors
    • Jakobsson J., Nielsen T.T., Staflin K., Georgievska B., Lundberg C. Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors. Gene Ther 2006, 13:966-973.
    • (2006) Gene Ther , vol.13 , pp. 966-973
    • Jakobsson, J.1    Nielsen, T.T.2    Staflin, K.3    Georgievska, B.4    Lundberg, C.5
  • 22
    • 69449095509 scopus 로고    scopus 로고
    • Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells
    • Keller A.F., Gravel M., Kriz J. Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells. Glia 2009, 57:1130-1142.
    • (2009) Glia , vol.57 , pp. 1130-1142
    • Keller, A.F.1    Gravel, M.2    Kriz, J.3
  • 23
    • 79953023267 scopus 로고    scopus 로고
    • Optimization of lentiviral vectors generation for biomedical and clinical research purposes: contemporary trends in technology development and applications
    • Kumar P., Woon-Khiong C. Optimization of lentiviral vectors generation for biomedical and clinical research purposes: contemporary trends in technology development and applications. Curr Gene Ther 2011, 11:144-153.
    • (2011) Curr Gene Ther , vol.11 , pp. 144-153
    • Kumar, P.1    Woon-Khiong, C.2
  • 24
    • 16244414899 scopus 로고    scopus 로고
    • Rabies virus receptors
    • Lafon M. Rabies virus receptors. J Neurovirol 2005, 11:82-87.
    • (2005) J Neurovirol , vol.11 , pp. 82-87
    • Lafon, M.1
  • 25
    • 77649273815 scopus 로고    scopus 로고
    • Recent advances in lentiviral vector development and applications
    • Matrai J., Chuah M.K., VandenDriessche T. Recent advances in lentiviral vector development and applications. Mol Ther 2010, 18:477-490.
    • (2010) Mol Ther , vol.18 , pp. 477-490
    • Matrai, J.1    Chuah, M.K.2    VandenDriessche, T.3
  • 26
    • 0034781791 scopus 로고    scopus 로고
    • Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery
    • Mazarakis N.D., Azzouz M., Rohll J.B., Ellard F.M., Wilkes F.J., Olsen A.L., et al. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Hum Mol Genet 2001, 10:2109-2121.
    • (2001) Hum Mol Genet , vol.10 , pp. 2109-2121
    • Mazarakis, N.D.1    Azzouz, M.2    Rohll, J.B.3    Ellard, F.M.4    Wilkes, F.J.5    Olsen, A.L.6
  • 28
    • 33748439119 scopus 로고    scopus 로고
    • Transduction of motor neurons and muscle fibers by intramuscular injection of HIV-1-based vectors pseudotyped with select rabies virus glycoproteins
    • Mentis G.Z., Gravell M., Hamilton R., Shneider N.A., O'Donovan M.J., Schubert M. Transduction of motor neurons and muscle fibers by intramuscular injection of HIV-1-based vectors pseudotyped with select rabies virus glycoproteins. J Neurosci Methods 2006, 157:208-217.
    • (2006) J Neurosci Methods , vol.157 , pp. 208-217
    • Mentis, G.Z.1    Gravell, M.2    Hamilton, R.3    Shneider, N.A.4    O'Donovan, M.J.5    Schubert, M.6
  • 29
    • 0032925296 scopus 로고    scopus 로고
    • Identification and transgenic analysis of a murine promoter that targets cholinergic neuron expression
    • Naciff J.M., Behbehani M.M., Misawa H., Dedman J.R. Identification and transgenic analysis of a murine promoter that targets cholinergic neuron expression. J Neurochem 1999, 72:17-28.
    • (1999) J Neurochem , vol.72 , pp. 17-28
    • Naciff, J.M.1    Behbehani, M.M.2    Misawa, H.3    Dedman, J.R.4
  • 30
    • 22144446344 scopus 로고    scopus 로고
    • Identification of a conserved 125 base-pair Hb9 enhancer that specifies gene expression to spinal motor neurons
    • Nakano T., Windrem M., Zappavigna V., Goldman S.A. Identification of a conserved 125 base-pair Hb9 enhancer that specifies gene expression to spinal motor neurons. Dev Biol 2005, 283:474-485.
    • (2005) Dev Biol , vol.283 , pp. 474-485
    • Nakano, T.1    Windrem, M.2    Zappavigna, V.3    Goldman, S.A.4
  • 31
    • 77957833643 scopus 로고    scopus 로고
    • Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
    • Reyes N.A., Fisher J.K., Austgen K., VandenBerg S., Huang E.J., Oakes S.A. Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis. J Clin Invest 2010, 120:3673-3679.
    • (2010) J Clin Invest , vol.120 , pp. 3673-3679
    • Reyes, N.A.1    Fisher, J.K.2    Austgen, K.3    VandenBerg, S.4    Huang, E.J.5    Oakes, S.A.6
  • 32
    • 74849087730 scopus 로고    scopus 로고
    • Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival
    • Shneider N.A., Brown M.N., Smith C.A., Pickel J., Alvarez F.J. Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival. Neural Dev 2009, 4:42.
    • (2009) Neural Dev , vol.4 , pp. 42
    • Shneider, N.A.1    Brown, M.N.2    Smith, C.A.3    Pickel, J.4    Alvarez, F.J.5
  • 33
    • 0034912492 scopus 로고    scopus 로고
    • Biological activity of mammalian transcriptional repressors
    • Thiel G., Lietz M., Bach K., Guethlein L., Cibelli G. Biological activity of mammalian transcriptional repressors. Biol Chem 2001, 382:891-902.
    • (2001) Biol Chem , vol.382 , pp. 891-902
    • Thiel, G.1    Lietz, M.2    Bach, K.3    Guethlein, L.4    Cibelli, G.5
  • 34
    • 0345825889 scopus 로고    scopus 로고
    • Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress
    • Tortarolo M., Crossthwaite A.J., Conforti L., Spencer J.P., Williams R.J., Bendotti C., et al. Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. J Neurochem 2004, 88:481-493.
    • (2004) J Neurochem , vol.88 , pp. 481-493
    • Tortarolo, M.1    Crossthwaite, A.J.2    Conforti, L.3    Spencer, J.P.4    Williams, R.J.5    Bendotti, C.6
  • 35
    • 0038383029 scopus 로고    scopus 로고
    • Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression
    • Tortarolo M., Veglianese P., Calvaresi N., Botturi A., Rossi C., Giorgini A., et al. Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression. Mol Cell Neurosci 2003, 23:180-192.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 180-192
    • Tortarolo, M.1    Veglianese, P.2    Calvaresi, N.3    Botturi, A.4    Rossi, C.5    Giorgini, A.6
  • 36
    • 15744393452 scopus 로고    scopus 로고
    • DNA looping in gene regulation: from the assembly of macromolecular complexes to the control of transcriptional noise
    • Vilar J.M., Saiz L. DNA looping in gene regulation: from the assembly of macromolecular complexes to the control of transcriptional noise. Curr Opin Genet Dev 2005, 15:136-144.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 136-144
    • Vilar, J.M.1    Saiz, L.2
  • 37
    • 0036113626 scopus 로고    scopus 로고
    • Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins
    • Watson D.J., Kobinger G.P., Passini M.A., Wilson J.M., Wolfe J.H. Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins. Mol Ther 2002, 5:528-537.
    • (2002) Mol Ther , vol.5 , pp. 528-537
    • Watson, D.J.1    Kobinger, G.P.2    Passini, M.A.3    Wilson, J.M.4    Wolfe, J.H.5
  • 38
    • 20544473329 scopus 로고    scopus 로고
    • Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein
    • Wilson J.M., Hartley R., Maxwell D.J., Todd A.J., Lieberam I., Kaltschmidt J.A., et al. Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci 2005, 25:5710-5719.
    • (2005) J Neurosci , vol.25 , pp. 5710-5719
    • Wilson, J.M.1    Hartley, R.2    Maxwell, D.J.3    Todd, A.J.4    Lieberam, I.5    Kaltschmidt, J.A.6
  • 39
    • 77955411795 scopus 로고    scopus 로고
    • Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves
    • Zhang Y., Zheng Y., Zhang Y.P., Shields L.B., Hu X., Yu P., et al. Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves. J Neurosci Res 2010, 88:2374-2384.
    • (2010) J Neurosci Res , vol.88 , pp. 2374-2384
    • Zhang, Y.1    Zheng, Y.2    Zhang, Y.P.3    Shields, L.B.4    Hu, X.5    Yu, P.6
  • 40
    • 0345700868 scopus 로고    scopus 로고
    • Lentiviral vectors for gene delivery to normal and demyelinated white matter
    • Zhao C., Strappe P.M., Lever A.M., Franklin R.J. Lentiviral vectors for gene delivery to normal and demyelinated white matter. Glia 2003, 42:59-67.
    • (2003) Glia , vol.42 , pp. 59-67
    • Zhao, C.1    Strappe, P.M.2    Lever, A.M.3    Franklin, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.