The Zollinger-Ellison Syndrome: Dangers and Consequences of Interrupting Antisecretory Treatment

Clinical Gastroenterology and Hepatology

Volumn 10, Issue 2, 2012, Pages 199-202

  Poitras, Pierre ^a   Gingras, Marie Hélène ^a   Rehfeld, Jens F ^b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Gastrinoma; Gastrointestinal Hormones; Neuroendocrine Tumor; Regulatory Peptides

Indexed keywords

BARIUM; CLOZAPINE; ESOMEPRAZOLE; GASTRIN; OCTREOTIDE; PANTOPRAZOLE; PENTETREOTIDE; PROTON PUMP INHIBITOR;

ABDOMINAL PAIN; ACUTE KIDNEY FAILURE; ADULT; ARTICLE; ASPIRATION BIOPSY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DIARRHEA; DISEASE SEVERITY; DRUG WITHDRAWAL; DUODENUM ULCER; DYSPHAGIA; ESOPHAGUS STRICTURE; GASTRIC HYPERACIDITY; GASTRIN BLOOD LEVEL; GASTRINOMA; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN TISSUE; HYPOVOLEMIC SHOCK; INTESTINE PERFORATION; LETHALITY; LIVER TUMOR; MALE; NEUROENDOCRINE TUMOR; PEPTIC ULCER; SCINTIGRAPHY; SOMATOSTATIN RECEPTOR SCINTIGRAPHY; STOMACH ACID SECRETION; STOMACH CANCER; VOMITING; ZOLLINGER ELLISON SYNDROME;

ESOPHAGEAL STENOSIS; HUMANS; INTESTINAL PERFORATION; MALE; MIDDLE AGED; PROTON PUMP INHIBITORS; WITHHOLDING TREATMENT; ZOLLINGER-ELLISON SYNDROME;

EID: 84856038551     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2011.08.012     Document Type: Article

References (17)

1. Zollinger R.M., Ellison E.H. Primary peptic ulcerations of the jejunum associated with islet cell tumours of the pancreas. Ann Surg 1955, 142:709-723.
2. Maton P.N. Review article: the management of Zollinger-Ellison syndrome. Aliment Pharmacol Ther 1993, 7:467-475.
3. Kaltsas G.A., Besser G.M., Grossman A.B. The diagnosis and medical management of advanced neuroendocrine tumors. Endocr Rev 2004, 25:458-511.
4. Metz D.C., Jensen R.T. Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. Gastroenterology 2008, 135:1469-1492.
5. Ellison E.C. Zollinger-Ellison syndrome: a personal perspective. Am Surg 2008, 74:563-571.
6. Ellison E.C. The Zollinger-Ellison syndrome: a comprehensive review of historical, scientific, and clinical considerations. Curr Probl Surg 2009, 46:1-95.
7. O'Toole D., Grossman A., Gross D., et al. ENETS (European Neuroendocrine Tumour Society) consensus guidelines for the standards of care in neuroendocrine tumors: biochemical markers. Neuroendocrinology 2009, 90:194-202.
8. Arnold R. Diagnosis and differential diagnosis of hypergastrinemia. Wein Klin Wochenschr 2007, 119:564-569.
9. Murugesan S.V., Varro A., Pritchard D.M. Review article: strategies to determine whether hypergastrinaemia is due to Zollinger-Ellison syndrome rather than a more common benign cause. Aliment Pharmacol Ther 2009, 29:1055-1068.
10. Goldman J.A., Blanton W.P., Hay D.W., et al. False-positive secretin stimulation test for gastrinoma associated with the use of proton pump inhibitor therapy. Clin Gastroenterol Hepatol 2009, 7:600-602.
11. Berna M.J., Hoffmann K.M., Long S.H., et al. Serum gastrin in Zollinger-Ellison syndrome: II. Prospective study of gastrin provocative testing in 293 patients from the National Institutes of Health and comparison with 537 cases from the literature. Evaluation of diagnostic criteria, proposal of new criteria, and correlations with clinical and tumoral features. Medicine (Baltimore) 2006, 85:331-364.
12. Poitras P., Tassé D. Management of patients with Zollinger-Ellison syndrome. Can J Gastroenterol 1989, 3:77-83.
13. Désir B., Poitras P. Oral pantoprazole for acid suppression in the treatment of patients with Zollinger-Ellison Syndrome. Can J Gastroenterol 2001, 15:795-798.
14. Jensen R.T. Consequences of long-term proton pump blockade: insights from studies of patients with gastrinomas. Basic Clin Pharmacol Toxicol 2006, 98:4-19.
15. Rehfeld J.F., Gingras M.H., Bardram L., et al. The Zollinger-Ellison syndrome and mismeasurement of gastrin. Gastroenterology 2011, 140:1444-1453.
16. Roy P.K., Venzon D.J., Feigenbaum K.M., et al. Gastric secretion in Zollinger-Ellison syndrome. Correlation with clinical expression, tumor extent and role in diagnosis-a prospective NIH study of 235 patients and a review of 984 cases in the literature. Medicine (Baltimore) 2001, 80:189-222.
17. Roy P.K., Venzon D.J., Shojamanesh H., et al. Zollinger-Ellison syndrome. Clinical presentation in 261 patients. Medicine (Baltimore) 2000, 79:379-411.