Zollinger-Ellison syndrome: Clinical presentation in 261 patients

Medicine

Volumn 79, Issue 6, 2000, Pages 379-411

  Roy, Praveen K ^a   Venzon, David J ^b   Shojamanesh, Houmayoun ^a   Abou Saif, Alaa ^a   Peghini, Paolo ^a   Doppman, John L ^c   Gibril, Fathia ^a   Jensen, Robert T ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE H2 RECEPTOR ANTAGONIST;

ABDOMINAL PAIN; ADULT; ARTICLE; CLINICAL FEATURE; DIARRHEA; DIFFERENTIAL DIAGNOSIS; FEMALE; GASTRECTOMY; HEARTBURN; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE ENDOCRINE NEOPLASIA; NEPHROLITHIASIS; ONSET AGE; PANCREAS TUMOR; PEPTIC ULCER; PRIORITY JOURNAL; STOMACH ACID SECRETION; ZOLLINGER ELLISON SYNDROME;

ABDOMINAL PAIN; ADULT; AGE DISTRIBUTION; AGE OF ONSET; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC ERRORS; DIARRHEA; GASTROESOPHAGEAL REFLUX; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; NAUSEA; PROSPECTIVE STUDIES; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; VOMITING; ZOLLINGER-ELLISON SYNDROME;

EID: 0033668418     PISSN: 00257974     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005792-200011000-00004     Document Type: Article

References (267)

1. Case records of the Massachusetts General Hospital: Case 3-1968
2. Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises. Case 47-1974
3. Case records of the Massachusetts General Hospital: Case 1-1976
4. AGA technical review on the evaluation and management of chronic diarrhea
5. Esophageal involvement in Zollinger-Ellison syndrome
6. Prospective study of somatostatin receptor scintigraphy and its effect on operative outcome in patients with Zollinger-Ellison syndrome
7. Neuroendocrine islet cell tumour producing gastrin and ACTH in a patient with calcifying chronic pancreatitis
8. Roentgenographic observations in the Zollinger-Ellison syndrome
9. Clinical course of symptomatic duodeno-jejunal Crohn's disease
10. Somatostatin analogue octreotide and inhibition of tumour growth in metastatic endocrine gastroenteropancreatic tumours
11. Apparent lymph node primary gastrinoma
12. The Zollinger-Ellison syndrome. Clinical, biological, and anatomical study of 10 cases
13. Syndrome de Zollinger-Ellison
14. Omeprazole in the Zollinger-Ellison syndrome
15. Frequency of endocrine disorders in patients with the Zollinger-Ellison syndrome
16. Zollinger-Ellison syndrome can be the initial endocrine manifestation in patients with multiple endocrine neoplasia-type 1
17. Stricture and perforation of the esophagus: Overlooked threats in the Zollinger-Ellison syndrome
18. The diagnosis of Zollinger-Ellison syndrome with special reference to the multiple endocrine adenomas
19. Metiamide treatment in five patients with Zollinger-Ellison syndrome
20. Severe peptic oesophagitis
21. Stenosing esophagitis in Zollinger-Ellison syndrome
22. Diagnosis of Zollinger-Ellison syndrome. From symptoms to biological evidence
23. Zollinger-Ellison syndrome; Clinical features and long-term follow-up
24. Barrett's esophagus: Age, prevalence, and extent of columnar epithelium
25. Prospective study of aggressive resection of metastatic pancreatic endocrine tumors
26. Cytology of islet tumours and hyperplasias associated with the Zollinger-Ellison syndrome
27. Positional cloning of the gene for multiple endocrine neoplasia-type 1
28. Selective venous sampling for gastrin to localize gastrinomas. A prospective study
29. A 7-year-old child with primary tumour localisation in the distal duodenum - New imaging procedures for an improved diagnosis
30. Zollinger-Ellison syndrome
31. Radiologic manifestations of ulcerogenic tumors of the pancreas. The Zollinger-Ellison syndrome
32. Clinical syndromes associated with tumors of the female genital tract
33. Malignant Zollinger-Ellison syndrome with gastrin-containing skin metastases
34. Comparison of ranitidine and cimetidine in the treatment of gastric hypersecretion
35. Gastric acid hypersecretion in refractory gastroesophageal reflux disease
36. Changing patterns in presentation and management of the Zollinger-Ellison syndrome in Northern Ireland, 1970-1988
37. Insulinoma
38. Physiologic responses to gastric acid hypersecretion in Zollinger-Ellison syndrome
39. Could the widespread use of proton pump inhibitors (PPI) mask, delay and/or complicate the diagnosis of Zollinger-Ellison syndrome (ZES)?
40. A case of pancreatitis associated with gastrinoma
41. Zollinger-Ellison syndrome
42. Use of calcium and secretin in the diagnosis of gastrinoma (Zollinger-Ellison syndrome)
43. The Zollinger-Ellison syndrome - 23 years later
44. Increased risk of nephrolithiasis in patients with steatorrhea
45. Relationship of gastrin processing to colon cancer
46. Radiologic manifestations of the Zollinger-Ellison syndrome
47. Severe peptic esophagitis in a patient with Zollinger-Ellison syndrome
48. Gastric hypersecretion, peptic ulceration and islet-cell tumor of the pancreas (The Zollinger-Ellison syndrome)
49. Surgical pathology of gastrinoma: Site, size, multicentricity, association with multiple endocrine neoplasia type 1, and malignancy
50. Diarrhee chronique ou steatorrhee manifestation inaugurale et revelatrice du syndrome de Zollinger-Ellison
51. Gastric emptying and secretion in Zollinger-Ellison syndrome
52. Early surgical treatment of gastrinoma
53. The ulcerogenic tumors of the pancreas
54. The Zollinger-Ellison syndrome: Re-appraisal and evaluation of 260 registered cases
55. Ulcerogenic tumor of the pancreas
56. Neuroendocrine pancreatic endocrine tumors. Clinical findings in a prospective study of 84 patients
57. Zollinger-Ellison syndrome with diarrhea as the predominant clinical feature
58. The Zollinger-Ellison syndrome. A collective surgical experience
59. Menetrier's disease complicated by development of the Zollinger-Ellison syndrome
60. Zollinger-Ellison syndrome. Relation to Helicobacter pylori-associated chronic gastritis and gastric acid secretion
61. Diarrhea
62. Assessment and prediction of long-term cure in patients with Zollinger-Ellison syndrome: The best approach
63. The influence of total gastrectomy on survival in malignant Zollinger-Ellison tumors
64. Surgical management of the Zollinger-Ellison syndrome
65. Pancreatic endocrine tumors
66. Clinical significance of hypergastrinaemia: Relevance to gastrin monitoring during omeprazole therapy
67. Changing approach to gastroenteropancreatic tumours. Case report of a gastrinoma metastasis localized by somatostatin-receptor scintigraphy
68. Tumors of the endocrine pancreas
69. Secretin and calcium provocative tests in the Zollinger-Ellison syndrome: A prospective study
70. Use of omeprazole in patients with the Zollinger-Ellison syndrome
71. Detection of duodenal gastrinomas by operative endoscopic transillumination: A prospective study
72. Pancreatitis associated with pancreatic carcinoma: A study of 26 cases
73. Zollinger-Ellison syndrome and neurofibromatosis in a 13-year-old boy
74. Chronic pancreatitis and pseudocyst formation secondary to carcinoid tumor of the pancreas
75. Metastatic gastrinomas: Localization with selective arterial injection of secretin
76. Specificity of somatostatin receptor scintigraphy: A prospective study and the effects of false positive localizations on management in patients with gastrinomas
77. Somatostatin receptor scintigraphy: Its sensitivity compared with that of other imaging methods in detecting primary and metastatic gastrinomas. A prospective study
78. Endoscopic diagnosis and removal of a duodenal wall gastrinoma
79. Prospective study of the value of serum chromogranin A or serum gastrin levels in assessment of the presence, extent, or growth of gastrinomas
80. Barrett's esophagus: Epidemiological and clinical results of a multicentric survey
81. Insulinoma
82. Zollinger-Ellison syndrome with interesting variations
83. Hypergastrinaemia evoked by omeprazole stimulates growth of gastric mucosa but not of pancreas of intestines in hamster, guinea pig and chicken
84. Gastrinoma presenting as chronic pancreatitis
85. Observations on steatorrhea associated with gastric hypersecretion and pancreatic islet cell neoplasm
86. Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumors of the endocrine pancreas
87. Gastrinoma
88. Gastrin-producing tumors
89. Management of the Zollinger-Ellison syndrome in patients with multiple endocrine neoplasia type 1
90. Diarrhea in neuroendocrine disorders
91. Natural history of digestive endocrine tumors
92. Overview of chronic diarrhea caused by functional neuroendocrine neoplasms
93. Use of omeprazole and other protein pump inhibitors in the Zollinger-Ellison syndrome
94. Treatment of pancreatic Zollinger-Ellison syndrome and other gastric hypersecretory states
95. Zollinger-Ellison syndrome
96. Zollinger-Ellison syndrome: Advances in treatment of the gastric hypersecretion and the gastrinoma
97. Zollinger-Ellison syndrome: Clinical presentation, pathology, diagnosis and treatment
98. Gastrinoma
99. Zollinger-Ellison syndrome: Current concepts and management
100. Definition of the role of somatostatin receptor scintigraphy in gastrointestinal neuroendocrine tumor localization
101. Endocrine neoplasms of the pancreas
102. Endocrine tumors of the pancreas
103. Esophageal acid sensitivity in Barrett's esophagus
104. Peripancreatic lymph node gastrinoma in a patient with Zollinger-Ellison syndrome
105. Primary gastrinoma of the liver
106. Gastrinomas: A 42-year experience
107. Zollinger-Ellison syndrome with esophagitis and barrett mucosa
108. Hypergastrinemia and colorectal carcinogenesis in the rat
109. Intestinal lactase deficiency and lactose intolerance in adults
110. Nutrient malabsorption in the Zollinger-Ellison Syndrome
111. Diarrhoea and reversible enteropathy in Zollinger-Ellison syndrome
112. Gastrinoma in a mesenteric lymph node
113. Hyperplastic gastropathy - Clinicopathological correlation
114. Somatostatin-receptor scintigraphy in gastroenteropancreatic tumors
115. Zollinger-Ellison syndrome caused by a duodenal wall tumour
116. The Zollinger-Ellison syndrome
117. Prevalence of endocrine abnormalities in patients with the Zollinger-Ellison syndrome and in their families
118. Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists
119. Gastrinomas and the change in their presentation and management in Northern Ireland, UK, from 1970 to 1996
120. Zollinger-Ellison syndrome presenting with osteomalacia
121. Long term follow up of patients with Zollinger-Ellisonsyndrome (ZES)
122. Perforation of a gastrojejunal ulcer into the pericardium
123. Zollinger-Ellison syndrome: Prospective assessment of abdominal US in the localization of gastrinomas
124. Failure to diagnose Zollinger-Ellison syndrome by pancreatic arteriography
125. A prospective study of surgical resection of duodenal and pancreatic gastrinomas in multiple endocrine neoplasia-type 1
126. Gastrinoma of the common bile duct: Immunohistochemical and ultrastructural study of a case
127. Intestinal mucosal function and structure in the steatorrhea of Zollinger-Ellison syndrome
128. Pancreatitis associated with neuroendocrine (islet cell) tumors of the pancreas
129. Zollinger-Ellison syndrome associated with pancreatic cystadenocarcinoma
130. Zollinger-Ellison syndrome in a Bantu woman with isolation of a gastrin-like substance from the primary and secondary tumors: Case report
131. Study of a primary gastrinoma in the common hepatic duct - A case report
132. Multiple endocrine neoplasia type 1: Clinical and genetic topics
133. Medical management of patients with Zollinger-Ellison syndrome who have had previous gastric surgery: A prospective study
134. Cushing's syndrome in patients with Zollinger-Ellison syndrome
135. Diagnosis and management of Zollinger-Ellison syndrome
136. H+-K+ ATPase inhibitors, anticholinergic agents, antidepressants and gastrin receptor antagonists as gastric acid antisecretory agents
137. Ovarian carcinoma as a cause of Zollinger-Ellison syndrome. Natural history, secretory products and response to provocative tests
138. Role of selective angiography in the management of Zollinger-Ellison syndrome
139. VIPomas and endocrine cholera: Clinical presentation, diagnosis, and advances in management
140. Steatorrhea associated with ulcerogenic tumor of the pancreas
141. Relationship between lower esophageal sphincter and serum gastrin concentration in Zollinger-Ellison syndrome and other clinical settings
142. H2-histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy
143. Trophic effects of gastrin on colorectal neoplasms in the rat
144. Secretin injection test in the diagnosis of gastrinoma
145. Changing concepts in the presentation, diagnosis and management of the Zollinger-Ellison syndrome
146. Advances in gastric antisecretory therapy in Zollinger-Ellison syndrome
147. Multiple endocrine neoplasia type 1: Clinical features and management
148. Flow cytometry and Zollinger-Ellison syndrome: Relationship to clinical course
149. Currently used doses of omeprazole in Zollinger-Ellison syndrome are too high
150. Use of omeprazole in Zollinger-Ellison: A prospective nine-year study of efficacy and safety
151. A reappraisal of the radiologic diagnosis of Zollinger-Ellison syndrome
152. Repeated vomiting of gastric juice in a patient with Zollinger-Ellison syndrome. Modifying influence upon clinical features
153. Diagnostic and therapeutic criteria in patients with Zollinger-Ellison syndrome and multiple endocrine neoplasia type 1
154. Management of islet cell tumors in patients with multiple endocrine neoplasia type 1
155. Clinical features and advances in biological diagnostic criteria for Zollinger-Ellison syndrome
156. Current approach to the management of tumoral process in patients with gastrinoma
157. Current approach to the management of gastrinoma and insulinoma in adults with multiple endocrine neoplasia type 1
158. Reflux esophagitis in Zollinger-Ellison syndrome is as frequent in France as in the United States
159. Zollinger-Ellison syndrome associated with ductal adenocarcinoma of the pancreas
160. Preoperative serum gastrin level as a prognostic indicator in Zollinger-Ellison syndrome
161. Zollinger-Ellison-syndrome. Advances in diagnosis and treatment
162. Reflux esophagitis in patients with Zollinger-Ellison syndrome
163. Roentgenographic findings in Zollinger-Ellison syndrome
164. Islet Cell adenoma and retention cyst: A rare cause of acute pancreatitis
165. Carcinoid tumor of the pancreas with obstructive pancreatitis
166. Cytoreductive hepatic surgery for metastatic gastrointestinal neuroendocrine tumors
167. Roentgenologic features of the Zollinger-Ellison syndrome - Ulcerogenic tumor of the pancreas
168. Parietal and chief cell population in four cases of the Zollinger-Ellison syndrome
169. Impact of stress on serum gastrin in Zollinger-Ellison syndrome
170. Advances in the management of Zollinger-Ellison syndrome
171. Intraoperative ultrasonographic localization of islet cell tumors. A prospective comparison to palpation
172. Surgical treatment of localized gastrinoma within the liver: A prospective study
173. Prospective study of gastrinoma localization and resection in patients with Zollinger-Ellison syndrome
174. Surgery to cure the Zollinger-Ellison syndrome
175. Surgery to cure the Zollinger-Ellison syndrome
176. Multiple endocrine neoplasia
177. Aggressive resection of metastatic disease in selected patients with malignant gastrinoma
178. Chronic obstructive pancreatitis, nesidioblastosis, and small endocrine pancreatic tumor
179. Syndrome de Zollinger-Ellison: Interet de l'endoscopie pour le diagnostic et la surveillance. A propos de 80 observations
180. Localization of pancreatic endocrine tumors
181. Imaging for pancreatic endocrine tumor localization: Recent advances
182. Prolonged hypergastrinemia does not increase the frequency of colonic neoplasia in patients with Zollinger-Ellison syndrome
183. Vasoactive intestinal polypeptide-secreting tumours: Biology and therapy
184. The diagnosis of the Zollinger-Ellison syndrome
185. Islet-cell tumour of pancreas associated with peptic ulceration
186. The Zollinger-Ellison syndrome. Its place in the pathophysiology of gastric acid secretion and of its hormonal regulation
187. Helicobacter pylori and peptic nicer disease
188. Barrett's esophagus. Natural history, incidence, etiology, and complications
189. Prospective comparative study of ability of MR imaging and other imaging modalities to localize tumors in patients with Zollinger-Ellison syndrome
190. Parietal cell mass and gastric acid secretion in the Zollinger-Ellison syndrome
191. Malignant islet cell tumour arising in chronic pancreatitis
192. Zollinger-Ellison tumor associated with a malabsorption syndrome
193. Zollinger-Ellison syndrome presenting as reflux esophagitis and stricture
194. Fluid secretion in the duodenum and intestinal handling of water and electrolytes in Zollinger-Ellison syndrome
195. Diarrhoea due to circulating agents
196. Diarrhoea and digestive endocrine tumours
197. Familial occurrence of the Zollinger-Ellison syndrome associated with diabetes
198. Zollinger-Ellison syndrome with diarrhea and malabsorption. Observations on a patient before and after pancreatic islet-cell tumour removal without resort to gastric surgery
199. A reappraisal of clinical, roentgenographic, and endoscopic features of the Zollinger-Ellison syndrome
200. Zollinger-Ellison syndrome with diabetes mellitus
201. Gastrin and colorectal cancer: A never-ending dispute?
202. Treatment of Zollinger-Ellison syndrome with exploratory laparotomy, proximal gastric vagotomy, and H2-receptor antagonists. A prospective study
203. Gastroesophageal reflux disease in the Zollinger-Ellison syndrome
204. The Zollinger-Ellison syndrome in children. A review
205. Gastric secretion in ulcerogenic tumors of the pancreas
206. Helicobacter pylori and the Zollinger-Ellison syndrome
207. Pancreatitis associated with pancreatic islet cell tumors
208. Management of islet cell tumors in patients with multiple endocrine neoplasia: A prospective study
209. The Zollinger-Ellison syndrome with steatorrhea. I. Anticholinergic treatment followed by total gastrectomy and colonic interposition
210. The Zollinger-Ellison syndrome with steatorrhea. II. The mechanism of fat and vitamin B 12 malabsorption
211. Nonfunctioning pancreatic neuroendocrine tumors presenting as pancreatitis: Report of four cases
212. Atrophic gastritis and its sequelae
213. Zollinger-Ellison syndrome presenting as esophageal stricture
214. Barrett's esophagus in children and young adults. Frequent association with mental retardation
215. Chronic endogenous hypergastrinemia in humans: Evidence for a mitogenic effect on the colonic mucosa
216. Mechanism of diarrhea in the Zollinger-Ellison syndrome, non-insulin-producing tumors of the pancreas
217. The gastrinoma/Zollinger-Ellison syndrome: Statistical evaluation of a Japanese series of 359 cases
218. Insulinomas/hypoglycemic syndrome: A statistical evaluation of 1085 reported cases of a Japanese series
219. Serum gastrin and human chorionic gonadotropin in the Zollinger-Ellison syndrome
220. Benign and malignant gastrinoma
221. The Zollinger-Ellison syndrome
222. The clinical diagnosis of the Zollinger-Ellison syndrome
223. Hyperoxaluria and intestinal disease. The role of steatorrhea and dietary calcium in regulating intestinal oxalate absorption
224. Esophageal function and occurrence of Barrett's esophagus in Zollinger-Ellison syndrome
225. The Brooklyn gastrinomas
226. Differential diagnosis of hypergastrinemia
227. A prospective study of intraoperative methods to diagnose and resect duodenal gastrinomas
228. Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet cell hyperplasia
229. Growth of newly diagnosed, untreated metastatic gastrinomas and predictors of growth patterns
230. Adenocarcinoma arising in Barrett's esophagus with Zollinger-Ellison syndrome
231. Primary hepatic gastrinoma
232. Duodenal gastrinoma - Clinical features and usefulness of selective arterial secretin injection test
233. Mixed ductal-endocrine carcinoma of the pancreas presenting as gastrinoma with Zollinger-Ellison syndrome: An autopsy case with a 24-year survival period
234. Distinguishing small hepatic hemangiomas from vascular liver metastases in patients with gastrinoma: Use of a somatostatin-receptor scintigraphic agent
235. Value of somatostatin receptor scintigraphy: A prospective study in gastrinoma of its effect on clinical management
236. Natural history and experience with diagnosis and treatment of the Zollinger-Ellison syndrome
237. Management of pancreatic endocrine tumors in patients with multiple endocrine neoplasia type 1
238. Duodenal gastrinomas, duodenotomy, and duodenal exploration in the surgical management of Zollinger-Ellison syndrome
239. Microgastrinomas of the duodenum. A cause of failed operations for the Zollinger-Ellison syndrome
240. Gastrin and colorectal cancer: A prospective study
241. Primary liver gastrinoma
242. Helicobacter pylori infection and duodenal ulcer disease
243. Ovarian cancers express and process progastrin
244. The Zollinger-Ellison syndrome: A review of the St. Vincent's hospital, Melbourne experience
245. Mechanisms of steatorrhea in the Zollinger-Ellison syndrome
246. Prospective study of the ability of computerized axial tomography to localize gastrinomas in patients with Zollinger-Ellison syndrome
247. Perforated jejunal ulcer and the Zollinger-Ellison syndrome
248. Zollinger-Ellison syndrome. An analysis of twenty-five cases
249. Pancreatic endocrine tumors and carcinoid tumors: Recent insights from genetic and molecular biologic studies
250. Studies on the interrelation between Zollinger-Ellison syndrome, Helicobacter pylori and proton pump inhibitor therapy
251. Determinants of metastatic rate and survival in patients with Zollinger-Ellison syndrome: A prospective long-term study
252. Surgery for the Zollinger-Ellison syndrome
253. Trophic action of gastrin on specific target cells in the gut
254. The role of surgery in children with the Zollinger-Ellison syndrome
255. Longevity studies following total gastrectomy. In children with the Zollinger-Ellison syndrome
256. Zollinger-Ellison syndrome: Current concepts in diagnosis and management
257. Zollinger-Ellison syndrome
258. A prospective analysis of the frequency, location, and curability of ectopic (non-pancreaticoduodenal, non-nodal) gastrinoma
259. A review of the Zollinger-Ellison syndrome - With particular reference to a patient treated with cimetidine
260. Zollinger-Ellison syndrome in a patient with normal screening gastrin level
261. Prospective study of the clinical course, prognostic factors and survival in patients with longstanding Zollinger-Ellison syndrome
262. Detection of the Zollinger-Ellison syndrome: The radiologist's responsibility
263. Brief report: A duodenal gastrinoma in a patient with diarrhea and normal serum gastrin concentrations
264. Pancreatic problems. 2. Chronic pancreatitis and pancreatic tumors
265. Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas
266. Ulcerogenic tumor of the pancreas
267. Observations on the postoperative tumor growth behavior of certain islet cell tumors