Now take a deep breath: Inhaled loxapine for the treatment of acute agitation

Journal of Psychosocial Nursing and Mental Health Services

Volumn 50, Issue 1, 2012, Pages 16-18

  Howland, Robert H ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84856030841     PISSN: 02793695     EISSN: None     Source Type: Journal    
DOI: 10.3928/02793695-20111213-05     Document Type: Article

References (10)

1. Allen, M.H., Feifel, D., Lesem, M.D., Zimbroff, D.L., Ross, R., Munzar, P., Cassella, J.V. (2011). Effcacy and safety of loxapine for inhalation in the treatment of agitation in patients with schizophrenia: A randomized double-blind placebo-controlled trial. Journal of Clinical Psychiatry, 72, 1313-1321.
2. Citrome, L. (2011). Aerosolised antipsychotic assuages agitation: Inhaled loxapine for agitation associated with schizophrenia or bipolar disorder. International Journal of Clinical Practice, 65, 330-340.
3. Dubin, W.R., & Weiss, K.J. (1986). Rapid tran-quilization: A comparison of thiothixene with loxapine. Journal of Clinical Psychiatry, 47, 294-297.
4. Glazer, W.M. (1999). Does loxapine have "atypical" properties? Clinical evidence. Journal of Clinical Psychiatry, 60(Suppl. 10), 42-46.
5. Lesem, M.D., Tran-Johnson, T.K., Riesenberg, R.A., Feifel, D., Allen, M.H., Fishman, R., Cassella, J.V. (2011). Rapid acute treatment of agitation in individuals with schizophrenia: Multicentre randomised placebo-controlled study of inhaled loxap-ine. British Journal of Psychiatry, 198, 51-58.
6. Patton, J.S., & Byron, P.R. (2007). Inhaling medicines: Delivering drugs to the body through the lungs. Nature Reviews Drug Discovery, 6, 67-74. doi:10.1038/nrd2153
7. Rabinowitz, J.D., Lloyd, P.M., Munzar, P., Rabi-nowitz, J.D., Lloyd, P.M., Munzar, P., Cas-sella, J.V. (2006). Ultra-fast absorption of amorphous pure drug aerosols via deep lung inhalation. Journal of Pharmaceutical Sciences, 95, 2438-2451.
8. Spyker, D.A., Munzar, P., & Cassella, J.V. (2010). Pharmacokinetics of loxapine following inhalation of a thermally generated aerosol in healthy volunteers. Journal of Clinical Pharmacology, 50, 169-179. doi:10.1177/0091270009347866
9. U.S. Food and Drug Administration. (2011a). December 12, 2011: Psychopharmacologic Drugs Advisory Committee meeting announcement. Retrieved from http://www.fda.gov/AdvisoryCommittees/Calendar/ucm277069.htm
10. U.S. Food and Drug Administration. (2011b). Memorandum: December 12, 2011 Meeting of the Psychopharmacologic Drugs Advisory Committee. Retrieved from http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/UCM282897.pdf