Effects of hydroxydecine® (10-hydroxy-2-decenoic acid) on skin barrier structure and function in vitro and clinical efficacy in the treatment of UV-induced xerosis

European Journal of Dermatology

Volumn 21, Issue 6, 2011, Pages 906-915

  Duplan, Hélène ^a   Questel, Emmanuel ^b   Hernandez Pigeon, Hélène ^a   Galliano, Marie Florence ^a   Caruana, Antony ^a   Ceruti, Isabelle ^a   Ambonati, Marco ^c   Mejean, Carine ^c   Damour, Odile ^d   Castex Rizzi, Nathalie ^a   Bessou Touya, Sandrine ^a   Schmitt, Anne Marie ^b  

^a Centre d'Immunologie Pierre Fabre   (France)

^b Centre de Recherche sur la Peau   (France)

^c Laboratoires Dermatologiques DUCRAY   (France)

^d EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

10 hydroxy 2 decenoic acid; Skin barrier dysfunction

Indexed keywords

10 HYDROXY 2 DECENOIC ACID; COLECALCIFEROL; FILAGGRIN; HYDROXYDECINE; ICTYANE; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INVOLUCRIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; THYMIC STROMAL LYMPHOPOIETIN; TRANSGLUTAMINASE 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CREAM; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG EFFICACY; DRUG SCREENING; DRY SKIN; EMULSION; EPIDERMIS; EXPLANT; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MALE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SKIN FUNCTION; SKIN INFLAMMATION; SKIN STRUCTURE; STRATUM CORNEUM; TREATMENT DURATION; ULTRAVIOLET RADIATION; VOLUNTEER; XEROSIS;

BODY WATER; CELL DIFFERENTIATION; EMOLLIENTS; EPIDERMIS; FATTY ACIDS, MONOUNSATURATED; HUMANS; IMMUNOHISTOCHEMISTRY; SKIN DISEASES; SKIN PHYSIOLOGICAL PROCESSES; ULTRAVIOLET RAYS;

EID: 84856021216     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2011.1531     Document Type: Article

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