High nuclear protein kinase Cθ expression may correlate with disease recurrence and poor survival in oral squamous cell carcinoma

Human Pathology

Volumn 43, Issue 2, 2012, Pages 276-281

  Chu, Pei Yi ^a,b   Hsu, Nicholas Chung Heng ^c   Tai, Hui Chun ^d   Yeh, Chung Min ^d   Lin, Shu Hui ^d   Hou, Ming Feng ^e,f   Yeh, Kun Tu ^d,e,g  

^a ST MARTIN DE PORRES HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^f KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Oral cancer; Overall survival; Protein kinas C ; Recurrence

Indexed keywords

PROTEIN KINASE C DELTA;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER SIZE; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; MOUTH SQUAMOUS CELL CARCINOMA; OVERALL SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; SURVIVAL TIME;

CARCINOMA, SQUAMOUS CELL; CELL NUCLEUS; CYTOPLASM; FEMALE; HUMANS; ISOENZYMES; KAPLAN-MEIER ESTIMATE; LYMPH NODES; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROTEIN KINASE C; SURVIVAL RATE; TAIWAN;

EID: 84856021065     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.05.001     Document Type: Article

References (32)

1. Y.H. Yang, C.H. Chen, and J.S. Chang Incidence rates of oral cancer and oral pre-cancerous lesions in a 6-year follow-up study of a Taiwanese aboriginal community J Oral Pathol Med 34 2005 596 601 (Pubitemid 41512945)
2. S. Fedele Diagnostic aids in the screening of oral cancer Head Neck Oncol 1 2009 5
3. W.L. Lo, S.Y. Kao, and L.Y. Chi Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival J Oral Maxillofac Surg 61 2003 751 758
4. I.C. Leite, and S. Koifman Survival analysis in a sample of oral cancer patients at a reference hospital in Rio de Janeiro, Brazil Oral Oncol 34 1998 347 352 (Pubitemid 28440295)
5. H. Mellor, and P.J. Parker The extended protein kinase C superfamily Biochem J 332 Pt 2 1998 281 292 (Pubitemid 28271856)
6. A.C. Newton Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions Chem Rev 101 2001 2353 2364 (Pubitemid 35373023)
7. Y. Nishizuka Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 258 1992 607 614
8. S. Ohno, and Y. Nishizuka Protein kinase C isotypes and their specific functions: prologue J Biochem 132 2002 509 511 (Pubitemid 35238901)
9. E.M. Griner, and M.G. Kazanietz Protein kinase C and other diacylglycerol effectors in cancer Nat Rev Cancer 7 2007 281 294 (Pubitemid 46480971)
10. A. Besson, and V.W. Yong Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression Mol Cell Biol 20 2000 4580 4590 (Pubitemid 30396106)
11. I. Gutcher, P.R. Webb, and N.G. Anderson The isoform-specific regulation of apoptosis by protein kinase C Cell Mol Life Sci 60 2003 1061 1070 (Pubitemid 36791911)
12. J. Koivunen, V. Aaltonen, and J. Peltonen Protein kinase C (PKC) family in cancer progression Cancer Lett 235 2006 1 10
13. R. Mandil, E. Ashkenazi, and M. Blass Protein kinase Calpha and protein kinase Cdelta play opposite roles in the proliferation and apoptosis of glioma cells Cancer Res 61 2001 4612 4619 (Pubitemid 32685797)
14. T. Ng, D. Shima, and A. Squire PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic EMBO J 18 1999 3909 3923 (Pubitemid 29335844)
15. Y. Nishizuka Protein kinase C and lipid signaling for sustained cellular responses FASEB J 9 1995 484 496
16. B. Scaglione-Sewell, C. Abraham, and M. Bissonnette Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells Cancer Res 58 1998 1074 1081 (Pubitemid 28182482)
17. M. Villalba, and A. Altman Protein kinase C-theta (PKC theta), a potential drug target for therapeutic intervention with human T cell leukemias Curr Cancer Drug Targets 2 2002 125 137
18. A. Altman, and M. Villalba Protein kinase C-θ (PKCθ): it's all about location, location, location Immunol Rev 192 2003 53 63 (Pubitemid 36613323)
19. L. Hilgenberg, and K. Miles Developmental regulation of a protein kinase C isoform localized in the neuromuscular junction J Cell Sci 108 Pt 1 1995 51 61
20. B. Sparatore, M. Patrone, and M. Passalacqua Neuronal differentiation of PC12 cells involves changes in protein kinase C-theta distribution and molecular properties Biochem Biophys Res Commun 275 2000 149 153 (Pubitemid 30663644)
21. C.R. Monks, H. Kupfer, and I. Tamir Selective modulation of protein kinase C-theta during T-cell activation Nature 385 1997 83 86 (Pubitemid 27024559)
22. C. Bertolotto, L. Maulon, and N. Filippa Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD J Biol Chem 275 2000 37246 37250 (Pubitemid 32002146)
23. M. Villalba, P. Bushway, and A. Altman Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD J Immunol 166 2001 5955 5963 (Pubitemid 32440719)
24. L. Deeds, S. Teodorescu, and M. Chu A p53-independent G1 cell cycle checkpoint induced by the suppression of protein kinase C alpha and theta isoforms J Biol Chem 278 2003 39782 39793 (Pubitemid 37248540)
25. A. Duensing, N.E. Joseph, and F. Medeiros Protein kinase C theta (PKC-theta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs) Cancer Res 64 2004 5127 5131 (Pubitemid 39006529)
26. P. Blay, A. Astudillo, and J.M. Buesa Protein kinase C theta is highly expressed in gastrointestinal stromal tumors but not in other mesenchymal neoplasias Clin Cancer Res 10 2004 4089 4095 (Pubitemid 38812487)
27. K.M. Kim, D.W. Kang, and W.S. Moon PKC[theta] expression in gastrointestinal stromal tumor Mod Pathol 19 2006 1480 1486 (Pubitemid 44624168)
28. C.T. Chiang, T.K. Chang, and Y.H. Hwang A critical exploration of blood and environmental chromium concentration among oral cancer patients in an oral cancer prevalent area of Taiwan Environ Geochem Health 2010 10.1007/s10653-010- 9346-2 [Epub ahead of print]
29. Y.C. Ko, Y.L. Huang, and C.H. Lee Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan J Oral Pathol Med 24 1995 450 453
30. A.M. Martelli, N. Sang, and P. Borgatti Multiple biological responses activated by nuclear protein kinase C J Cell Biochem 74 1999 499 521 (Pubitemid 29372491)
31. P.K. Gill, A. Gescher, and T.W. Gant Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta Eur J Biochem 268 2001 4151 4157 (Pubitemid 32862875)
32. K. Belguise, and G.E. Sonenshein PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis J Clin Invest 117 2007 4009 4021 (Pubitemid 350224110)