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Volumn , Issue , 2010, Pages 200-209

Functional Brain Imaging Studies in Bipolar Disorder: Focus on Cerebral Metabolism and Blood Flow

Author keywords

Cerebral blood flow and metabolism across affective states; Cerebral blood flow studies in bipolar depression; Cerebral blood flow studies in euthymic bipolar disorder patients; Cerebral metabolism studies in mania; Dorsolateral prefrontal and oribitofrontal circuits; Functional brain imaging studies in bipolar disorder and cerebral metabolism; Single photon emission computed tomography (SPECT)

Indexed keywords


EID: 84855999787     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470661277.ch15     Document Type: Chapter
Times cited : (6)

References (63)
  • 1
    • 33646193782 scopus 로고    scopus 로고
    • Brain network dysfunction in bipolar disorder
    • Adler, C.M., DelBello, M.P. and Strakowski, S.M. (2006) Brain network dysfunction in bipolar disorder. CNS Spectrums, 11 (4), 312-320.
    • (2006) CNS Spectrums , vol.11 , Issue.4 , pp. 312-320
    • Adler, C.M.1    DelBello, M.P.2    Strakowski, S.M.3
  • 2
    • 74349101913 scopus 로고    scopus 로고
    • Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder
    • Brooks, J.O., Hoblyn, J.C., Woodard, S.A. et al. (2009) Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder. J. Psychiatr. Res., 94, 32-37.
    • (2009) J. Psychiatr. Res. , vol.94 , pp. 32-37
    • Brooks, J.O.1    Hoblyn, J.C.2    Woodard, S.A.3
  • 3
    • 0030858270 scopus 로고    scopus 로고
    • Limbic-Cortical dysregulation: A proposed model of depression
    • Mayberg, H.S. (1997) Limbic-Cortical dysregulation: A proposed model of depression. J. Neuropsych. Clin. N., 9 (3), 471-481.
    • (1997) J. Neuropsych. Clin. N. , vol.9 , Issue.3 , pp. 471-481
    • Mayberg, H.S.1
  • 4
    • 12344250469 scopus 로고    scopus 로고
    • The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings
    • Strakowski, S.M., Delbello, M.P. and Adler, C.M. (2005) The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings. Mol. Psychiatry, 10 (1), 105-116.
    • (2005) Mol. Psychiatry , vol.10 , Issue.1 , pp. 105-116
    • Strakowski, S.M.1    Delbello, M.P.2    Adler, C.M.3
  • 5
    • 0025613142 scopus 로고
    • Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions
    • Alexander, G.E., Crutcher, M.D. and DeLong, M.R. (1990) Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. Prog. Brain Res., 85, 119-146.
    • (1990) Prog. Brain Res. , vol.85 , pp. 119-146
    • Alexander, G.E.1    Crutcher, M.D.2    DeLong, M.R.3
  • 6
    • 57749204561 scopus 로고    scopus 로고
    • Decreased prefrontal, anterior cingulate, insula, and ventral striatal metabolism in medication-free depressed outpatients with bipolar disorder
    • Brooks, J.O., Wang, P.W., Bonner, J.C. et al. (2009) Decreased prefrontal, anterior cingulate, insula, and ventral striatal metabolism in medication-free depressed outpatients with bipolar disorder. J. Psychiatr. Res., 43 (3), 181-188.
    • (2009) J. Psychiatr. Res. , vol.43 , Issue.3 , pp. 181-188
    • Brooks, J.O.1    Wang, P.W.2    Bonner, J.C.3
  • 7
    • 0028036428 scopus 로고
    • Frontal-Subcortical circuits and neuropsychiatric disorders
    • Mega, M.S. and Cummings, J.L. (1994) Frontal-Subcortical circuits and neuropsychiatric disorders. J. Neuropsych. Clin. N., 6 (4), 358-370.
    • (1994) J. Neuropsych. Clin. N. , vol.6 , Issue.4 , pp. 358-370
    • Mega, M.S.1    Cummings, J.L.2
  • 8
    • 0034625673 scopus 로고    scopus 로고
    • Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control
    • MacDonald, A.W., Cohen, J.D., Stenger, V.A. and Carter, C.S. (2000) Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science, 288 (5472), 1835-1838.
    • (2000) Science , vol.288 , Issue.5472 , pp. 1835-1838
    • MacDonald, A.W.1    Cohen, J.D.2    Stenger, V.A.3    Carter, C.S.4
  • 9
    • 0030935403 scopus 로고    scopus 로고
    • Subgenual prefrontal cortex abnormalities in mood disorders
    • Drevets, W.C., Price, J.L., Simpson, J.R. et al. (1997) Subgenual prefrontal cortex abnormalities in mood disorders. Nature, 386 (6627), 824-827.
    • (1997) Nature , vol.386 , Issue.6627 , pp. 824-827
    • Drevets, W.C.1    Price, J.L.2    Simpson, J.R.3
  • 10
    • 34548039062 scopus 로고    scopus 로고
    • Resting- State functional connectivity in major depression: Abnormally increased contributions from subgenual cingulate cortex and thalamus
    • Greicius, M.D., Flores, B.H., Menon, V. et al. (2007) Resting- State functional connectivity in major depression: Abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol. Psychiatry, 62 (5), 429-437.
    • (2007) Biol. Psychiatry , vol.62 , Issue.5 , pp. 429-437
    • Greicius, M.D.1    Flores, B.H.2    Menon, V.3
  • 11
    • 42449097200 scopus 로고    scopus 로고
    • Medication effects in neuroimaging studies of bipolar disorder
    • Phillips, M.L., Travis, M.J., Fagiolini, A. and Kupfer, D.J. (2008) Medication effects in neuroimaging studies of bipolar disorder. Am. J. Psychiatry, 165 (3), 313-320.
    • (2008) Am. J. Psychiatry , vol.165 , Issue.3 , pp. 313-320
    • Phillips, M.L.1    Travis, M.J.2    Fagiolini, A.3    Kupfer, D.J.4
  • 12
    • 0021815444 scopus 로고
    • Cerebral metabolic rates for glucose in mood disorders. Studies with positron emission tomography and fluorodeoxyglucose F 18
    • Baxter, L.R., Phelps, M.E., Mazziotta, J.C. et al. (1985) Cerebral metabolic rates for glucose in mood disorders. Studies with positron emission tomography and fluorodeoxyglucose F 18. Arch. Gen. Psychiatry, 42 (5), 441-447.
    • (1985) Arch. Gen. Psychiatry , vol.42 , Issue.5 , pp. 441-447
    • Baxter, L.R.1    Phelps, M.E.2    Mazziotta, J.C.3
  • 13
    • 0021340932 scopus 로고
    • Positron emission tomographic image measurement in schizophrenia and affective disorders
    • Buchsbaum, M.S., Cappelletti, J., Ball, R. et al. (1984) Positron emission tomographic image measurement in schizophrenia and affective disorders. Ann. Neurol, (15 Suppl), S157-S165.
    • (1984) Ann. Neurol , Issue.15 SUPPL.
    • Buchsbaum, M.S.1    Cappelletti, J.2    Ball, R.3
  • 14
    • 0022477071 scopus 로고
    • Frontal cortex and basal ganglia metabolic rates assessed by positron emission tomography with [18F]2-deoxyglucose in affective illness
    • Buchsbaum, M.S., Wu, J., DeLisi, L.E. et al. (1986) Frontal cortex and basal ganglia metabolic rates assessed by positron emission tomography with [18F]2-deoxyglucose in affective illness. J. Affect. Disord., 10 (2), 137-152.
    • (1986) J. Affect. Disord. , vol.10 , Issue.2 , pp. 137-152
    • Buchsbaum, M.S.1    Wu, J.2    DeLisi, L.E.3
  • 15
    • 0024828787 scopus 로고
    • Evidence for common alterations in cerebral glucose metabolism in major affective disorders and schizophrenia
    • Cohen, R.M., Semple, W.E., Gross, M. et al. (1989) Evidence for common alterations in cerebral glucose metabolism in major affective disorders and schizophrenia. Neuropsychopharmacology, 2 (4), 241-254.
    • (1989) Neuropsychopharmacology , vol.2 , Issue.4 , pp. 241-254
    • Cohen, R.M.1    Semple, W.E.2    Gross, M.3
  • 16
    • 0035863256 scopus 로고    scopus 로고
    • Effects of mood and subtype on cerebral glucose metabolism in treatment-resistant bipolar disorder
    • Ketter, T.A., Kimbrell, T.A., George, M.S. et al. (2001) Effects of mood and subtype on cerebral glucose metabolism in treatment-resistant bipolar disorder. Biol. Psychiatry, 49 (2), 97-109.
    • (2001) Biol. Psychiatry , vol.49 , Issue.2 , pp. 97-109
    • Ketter, T.A.1    Kimbrell, T.A.2    George, M.S.3
  • 17
    • 0025053032 scopus 로고
    • Left prefrontal glucose hypometabolism in the depressed state: A confirmation
    • Martinot, J.L., Hardy, P., Feline, A. et al. (1990) Left prefrontal glucose hypometabolism in the depressed state: A confirmation. Am. J. Psychiatry, 147 (10), 1313-1317.
    • (1990) Am. J. Psychiatry , vol.147 , Issue.10 , pp. 1313-1317
    • Martinot, J.L.1    Hardy, P.2    Feline, A.3
  • 18
    • 0030298319 scopus 로고    scopus 로고
    • Gender differences in regional cerebral blood flow during transient self-induced sadness or happiness
    • George, M.S., Ketter, T.A., Parekh, P.I. et al. (1996) Gender differences in regional cerebral blood flow during transient self-induced sadness or happiness. Biol. Psychiatry, 40 (9), 859-871.
    • (1996) Biol. Psychiatry , vol.40 , Issue.9 , pp. 859-871
    • George, M.S.1    Ketter, T.A.2    Parekh, P.I.3
  • 19
    • 0027413760 scopus 로고
    • A test-retest study of cerebral blood flow during somatosensory stimulation in depressed patients with schizophrenia and major depression
    • Ebert, D., Feistel, H., Barocka, A. et al. (1993) A test-retest study of cerebral blood flow during somatosensory stimulation in depressed patients with schizophrenia and major depression. Eur. Arch. Psy. Clin. N., 242 (4), 250-254.
    • (1993) Eur. Arch. Psy. Clin. N. , vol.242 , Issue.4 , pp. 250-254
    • Ebert, D.1    Feistel, H.2    Barocka, A.3
  • 20
    • 0029978042 scopus 로고    scopus 로고
    • Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique
    • Ito, H., Kawashima, R., Awata, S. et al. (1996) Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique. J. Nucl. Med., 37 (3), 410-414.
    • (1996) J. Nucl. Med. , vol.37 , Issue.3 , pp. 410-414
    • Ito, H.1    Kawashima, R.2    Awata, S.3
  • 21
    • 0026650353 scopus 로고
    • Preliminary data on the metabolic brain pattern of patients with winter seasonal affective disorder
    • Cohen, R.M., Gross, M., Nordahl, T.E. et al. (1992) Preliminary data on the metabolic brain pattern of patients with winter seasonal affective disorder. Arch. Gen. Psychiatry, 49 (7), 545-552.
    • (1992) Arch. Gen. Psychiatry , vol.49 , Issue.7 , pp. 545-552
    • Cohen, R.M.1    Gross, M.2    Nordahl, T.E.3
  • 22
    • 0026644617 scopus 로고
    • Cerebral glucose metabolism in patients with summer seasonal affective disorder
    • Goyer, P.F., Schulz, P.M., Semple, W.E. et al. (1992) Cerebral glucose metabolism in patients with summer seasonal affective disorder. J. Nuc. Med., 7 (3), 233-240.
    • (1992) J. Nuc. Med. , vol.7 , Issue.3 , pp. 233-240
    • Goyer, P.F.1    Schulz, P.M.2    Semple, W.E.3
  • 23
    • 0032575978 scopus 로고    scopus 로고
    • Changes in regional cerebral blood flow demonstrated by single photon emission computed tomography in depressive disorders: Comparison of unipolar vs
    • Tutus, A., Simsek, A., Sofuoglu, S. et al. (1998) Changes in regional cerebral blood flow demonstrated by single photon emission computed tomography in depressive disorders: Comparison of unipolar vs. Bipolar Subtypes. Psychiatry Res., 83 (3), 169-177.
    • (1998) Bipolar Subtypes. Psychiatry Res. , vol.83 , Issue.3 , pp. 169-177
    • Tutus, A.1    Simsek, A.2    Sofuoglu, S.3
  • 24
    • 60049101442 scopus 로고    scopus 로고
    • Brain glucose metabolism difference between bipolar and unipolar mood disorders in depressed and euthymic states
    • Hosokawa, T., Momose, T. and Kasai, K. (2008) Brain glucose metabolism difference between bipolar and unipolar mood disorders in depressed and euthymic states. Prog. Neuropsychopharmacol. Biol. Psychiatry, 33 (2), 243-250.
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , Issue.2 , pp. 243-250
    • Hosokawa, T.1    Momose, T.2    Kasai, K.3
  • 25
    • 33847268162 scopus 로고    scopus 로고
    • Regional cerebral glucose metabolic abnormalities in bipolar II depression
    • Mah, L., Zarate, C.A., Singh, J. et al. (2007) Regional cerebral glucose metabolic abnormalities in bipolar II depression. Biol. Psychiatry, 61 (6), 765-775.
    • (2007) Biol. Psychiatry , vol.61 , Issue.6 , pp. 765-775
    • Mah, L.1    Zarate, C.A.2    Singh, J.3
  • 26
    • 33646566350 scopus 로고    scopus 로고
    • Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controls
    • Brooks, J.O., Wang, P.W., Strong, C. et al. (2006) Preliminary evidence of differential relations between prefrontal cortex metabolism and sustained attention in depressed adults with bipolar disorder and healthy controls. Bipolar Disord., 8 (3), 248-254.
    • (2006) Bipolar Disord. , vol.8 , Issue.3 , pp. 248-254
    • Brooks, J.O.1    Wang, P.W.2    Strong, C.3
  • 27
    • 0024508732 scopus 로고
    • Reduction of prefrontal cortex glucose metabolism common to three types of depression
    • Baxter, L.R., Schwartz, J.M., Phelps, M.E. et al. (1989) Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch. Gen. Psychiatry, 46 (3), 243-250.
    • (1989) Arch. Gen. Psychiatry , vol.46 , Issue.3 , pp. 243-250
    • Baxter, L.R.1    Schwartz, J.M.2    Phelps, M.E.3
  • 28
    • 0023095954 scopus 로고
    • Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls
    • Baxter, L.R., Phelps, M.E., Mazziotta, J.C. et al. (1987) Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls. Arch. Gen. Psychiatry, 44 (3), 211-218.
    • (1987) Arch. Gen. Psychiatry , vol.44 , Issue.3 , pp. 211-218
    • Baxter, L.R.1    Phelps, M.E.2    Mazziotta, J.C.3
  • 29
    • 0028069191 scopus 로고
    • Frontal and parietal metabolic disturbances in unipolar depression
    • Biver, F., Goldman, S., Delvenne, V. et al. (1994) Frontal and parietal metabolic disturbances in unipolar depression. Biol. Psychiatry, 36 (6), 381-388.
    • (1994) Biol. Psychiatry , vol.36 , Issue.6 , pp. 381-388
    • Biver, F.1    Goldman, S.2    Delvenne, V.3
  • 30
    • 0026705402 scopus 로고
    • A functional anatomical study of unipolar depression
    • Drevets, W.C., Videen, T.O., Price, J.L. et al. (1992) A functional anatomical study of unipolar depression. Neuropsychopharmacology, 12 (9), 3628-3641.
    • (1992) Neuropsychopharmacology , vol.12 , Issue.9 , pp. 3628-3641
    • Drevets, W.C.1    Videen, T.O.2    Price, J.L.3
  • 31
    • 0036159139 scopus 로고    scopus 로고
    • Glucose metabolism in the amygdala in depression: Relationship to diagnostic subtype and plasma cortisol levels
    • Drevets, W.C., Price, J.L., Bardgett, M.E. et al. (2002) Glucose metabolism in the amygdala in depression: Relationship to diagnostic subtype and plasma cortisol levels. Pharmacol. Biochem. Behav., 71 (3), 431-447.
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , Issue.3 , pp. 431-447
    • Drevets, W.C.1    Price, J.L.2    Bardgett, M.E.3
  • 32
    • 0344011517 scopus 로고    scopus 로고
    • State and trait influences on mood regulation in bipolar disorder: Blood flow differences with an acute mood challenge
    • Krüger, S., Seminowicz, D., Goldapple, K. et al. (2003) State and trait influences on mood regulation in bipolar disorder: Blood flow differences with an acute mood challenge. Biol. Psychiatry, 54 (11), 1274-1283.
    • (2003) Biol. Psychiatry , vol.54 , Issue.11 , pp. 1274-1283
    • Krüger, S.1    Seminowicz, D.2    Goldapple, K.3
  • 33
    • 27544505353 scopus 로고    scopus 로고
    • Preliminary findings of uncoupling of flow and metabolism in unipolar compared with bipolar affective illness and normal controls
    • Dunn, R.T., Willis, M.W., Benson, B.E. et al. (2005) Preliminary findings of uncoupling of flow and metabolism in unipolar compared with bipolar affective illness and normal controls. Psychiatry Res., 140 (2), 181-198.
    • (2005) Psychiatry Res. , vol.140 , Issue.2 , pp. 181-198
    • Dunn, R.T.1    Willis, M.W.2    Benson, B.E.3
  • 34
    • 0026707293 scopus 로고
    • Single photon emission tomography with 99mtc-exametazime in major depression and the pattern of brain activity underlying the psychotic/neurotic continuum
    • Austin, M.P., Dougall, N., Ross, M. et al. (1992) Single photon emission tomography with 99mtc-exametazime in major depression and the pattern of brain activity underlying the psychotic/neurotic continuum. J. Affect. Disord., 26 (1), 31-43.
    • (1992) J. Affect. Disord. , vol.26 , Issue.1 , pp. 31-43
    • Austin, M.P.1    Dougall, N.2    Ross, M.3
  • 35
    • 0027326614 scopus 로고
    • Regional cerebral blood flow in depression measured by positron emission tomography: The relationship with clinical dimensions
    • Bench, C.J., Friston, K.J., Brown, R.G. et al. (1993) Regional cerebral blood flow in depression measured by positron emission tomography: The relationship with clinical dimensions. Psychol. Med., 23 (3), 579-590.
    • (1993) Psychol. Med. , vol.23 , Issue.3 , pp. 579-590
    • Bench, C.J.1    Friston, K.J.2    Brown, R.G.3
  • 36
    • 18244426740 scopus 로고    scopus 로고
    • Cerebral hypoperfusion in medication resistant, depressed patients assessed by tc99m HMPAO SPECT
    • Bonne, O., Krausz, Y., Gorfine, M. et al. (1996) Cerebral hypoperfusion in medication resistant, depressed patients assessed by tc99m HMPAO SPECT. J. Affect. Disord., 41 (3), 163-171.
    • (1996) J. Affect. Disord. , vol.41 , Issue.3 , pp. 163-171
    • Bonne, O.1    Krausz, Y.2    Gorfine, M.3
  • 37
    • 0031557101 scopus 로고    scopus 로고
    • Quantitative regional cerebral flow measured by tc-99m HMPAO SPECT in mood disorder
    • Iidaka, T., Nakajima, T., Suzuki, Y. et al. (1997) Quantitative regional cerebral flow measured by tc-99m HMPAO SPECT in mood disorder. Psychiatry Res., 68 (2-3), 143-154.
    • (1997) Psychiatry Res. , vol.68 , Issue.2-3 , pp. 143-154
    • Iidaka, T.1    Nakajima, T.2    Suzuki, Y.3
  • 38
    • 0025670551 scopus 로고
    • Regional cerebral blood flow in depression
    • Kanaya, T. and Yonekawa, M. (1990) Regional cerebral blood flow in depression. Jpn. J. Psychiatry. Neurol., 44 (3), 571-576.
    • (1990) Jpn. J. Psychiatry. Neurol. , vol.44 , Issue.3 , pp. 571-576
    • Kanaya, T.1    Yonekawa, M.2
  • 39
    • 0036468609 scopus 로고    scopus 로고
    • Regional cerebral glucose utilization in patients with a range of severities of unipolar depression
    • Kimbrell, T.A., Ketter, T.A., George, M.S. et al. (2002) Regional cerebral glucose utilization in patients with a range of severities of unipolar depression. Biol. Psychiatry, 51 (3), 237-252.
    • (2002) Biol. Psychiatry , vol.51 , Issue.3 , pp. 237-252
    • Kimbrell, T.A.1    Ketter, T.A.2    George, M.S.3
  • 40
    • 0024465963 scopus 로고
    • Single photon emission computed tomography (SPECT) with [123I]IMP in the differential diagnosis of psychiatric disorders
    • O'Connell, R.A., Van Heertum, R.L., Billick, S.B. et al. (1989) Single photon emission computed tomography (SPECT) with [123I]IMP in the differential diagnosis of psychiatric disorders. J. Neuropsych. Clin. N., 1 (2), 145-153.
    • (1989) J. Neuropsych. Clin. N. , vol.1 , Issue.2 , pp. 145-153
    • O'Connell, R.A.1    Van Heertum, R.L.2    Billick, S.B.3
  • 41
    • 0028930945 scopus 로고
    • Single-Photon emission computed tomography of the brain in acute mania and schizophrenia
    • O'Connell, R.A., Van Heertum, R.L., Luck, D. et al. (1995) Single-Photon emission computed tomography of the brain in acute mania and schizophrenia. J. Neuroimaging, 5 (2), 101-104.
    • (1995) J. Neuroimaging , vol.5 , Issue.2 , pp. 101-104
    • O'Connell, R.A.1    Van Heertum, R.L.2    Luck, D.3
  • 42
    • 0024364858 scopus 로고
    • Regional cerebral blood flow in depression: Associations with psychopathology
    • Schlegel, S., Aldenhoff, J.B., Eissner, D. et al. (1989) Regional cerebral blood flow in depression: Associations with psychopathology. J. Affect. Disord., 17 (3), 211-218.
    • (1989) J. Affect. Disord. , vol.17 , Issue.3 , pp. 211-218
    • Schlegel, S.1    Aldenhoff, J.B.2    Eissner, D.3
  • 43
    • 0026676463 scopus 로고
    • Assessment of changes in regional cerebral blood flow in patients with major depression using the 99mtc-hmpao single photon emission tomography method
    • Yazici, K.M., Kapucu, O., Erbas, B. et al. (1992) Assessment of changes in regional cerebral blood flow in patients with major depression using the 99mtc-hmpao single photon emission tomography method. Eur. J. Nucl. Med., 19 (12), 1038-1043.
    • (1992) Eur. J. Nucl. Med. , vol.19 , Issue.12 , pp. 1038-1043
    • Yazici, K.M.1    Kapucu, O.2    Erbas, B.3
  • 44
    • 0027196158 scopus 로고
    • Regional cerebral bloodflowin unipolar depression measured with tc- 99m-hmpao single photon emission computed tomography: Negative findings
    • Maes, M., Dierckx, R., Meltzer, H.Y. et al. (1993) Regional cerebral bloodflowin unipolar depression measured with tc- 99m-hmpao single photon emission computed tomography: Negative findings. Psychiatry Res., 50 (2), 77-88.
    • (1993) Psychiatry Res. , vol.50 , Issue.2 , pp. 77-88
    • Maes, M.1    Dierckx, R.2    Meltzer, H.Y.3
  • 45
    • 0028264040 scopus 로고
    • Paralimbic hypoperfusion in unipolar depression
    • Mayberg, H.S., Lewis, P.J., Regenold, W. and Wagner, H.N. (1994) Paralimbic hypoperfusion in unipolar depression. J. Nuc. Med., 35 (6), 929-934.
    • (1994) J. Nuc. Med. , vol.35 , Issue.6 , pp. 929-934
    • Mayberg, H.S.1    Lewis, P.J.2    Regenold, W.3    Wagner, H.N.4
  • 46
    • 0027337925 scopus 로고
    • 99Mtc-Hmpao single photon emission tomography in late life depression: A pilot study of regional cerebral blood flow at rest and during a verbal fluency task
    • Philpot, M.P., Banerjee, S., Needham-Bennett, H. et al. (1993) 99Mtc-Hmpao single photon emission tomography in late life depression: A pilot study of regional cerebral blood flow at rest and during a verbal fluency task. J. Affect. Disord., 28 (4), 233-240.
    • (1993) J. Affect. Disord. , vol.28 , Issue.4 , pp. 233-240
    • Philpot, M.P.1    Banerjee, S.2    Needham-Bennett, H.3
  • 47
    • 0027142511 scopus 로고
    • Cerebral blood flow in major depression and dysthymia
    • Thomas, P., Vaiva, G., Samaille, E. et al. (1993) Cerebral blood flow in major depression and dysthymia. J. Affect. Disord., 29 (4), 235-242.
    • (1993) J. Affect. Disord. , vol.29 , Issue.4 , pp. 235-242
    • Thomas, P.1    Vaiva, G.2    Samaille, E.3
  • 48
    • 0030070943 scopus 로고    scopus 로고
    • Focal cerebral perfusion defects demonstrated by 99mtc-hexamethylpropyleneamine oxime SPECT in elderly depressed patients
    • Vasile, R.G., Schwartz, R.B., Garada, B. et al. (1996) Focal cerebral perfusion defects demonstrated by 99mtc-hexamethylpropyleneamine oxime SPECT in elderly depressed patients. Psychiatry Res., 67 (1), 59-70.
    • (1996) Psychiatry Res. , vol.67 , Issue.1 , pp. 59-70
    • Vasile, R.G.1    Schwartz, R.B.2    Garada, B.3
  • 49
    • 0029781727 scopus 로고    scopus 로고
    • Limbic dysfunction in schizophrenia and mania. A study using 18f-labelled fluorodeoxyglucose and positron emission tomography
    • Al-Mousawi, A.H., Evans, N., Ebmeier, K.P. et al. (1996) Limbic dysfunction in schizophrenia and mania. A study using 18f-labelled fluorodeoxyglucose and positron emission tomography. Brit. J. Psychiat., 169 (4), 509-516.
    • (1996) Brit. J. Psychiat. , vol.169 , Issue.4 , pp. 509-516
    • Al-Mousawi, A.H.1    Evans, N.2    Ebmeier, K.P.3
  • 50
    • 75149185992 scopus 로고    scopus 로고
    • Cerebral metabolic evidence of corticolimbic dysregulation in bipolar mania
    • Brooks, J. O. III, Hoblyn, J. C., and Ketter, T. A. (2010) Cerebral metabolic evidence of corticolimbic dysregulation in bipolar mania. Psychiatry Research: Neuroimaging, 181, 136-140.
    • (2010) Psychiatry Research: Neuroimaging , vol.181 , pp. 136-140
    • Brooks III, J.O.1    Hoblyn, J.C.2    Ketter, T.A.3
  • 51
    • 0024511446 scopus 로고
    • Regional cerebral blood flow in depression and mania
    • Silfverskiöld, P. and Risberg, J. (1989) Regional cerebral blood flow in depression and mania. Arch. Gen. Psychiatry, 46 (3), 253-259.
    • (1989) Arch. Gen. Psychiatry , vol.46 , Issue.3 , pp. 253-259
    • Silfverskiöld, P.1    Risberg, J.2
  • 52
    • 0029063346 scopus 로고
    • Regional cerebral blood flow in mood disorders: IV. Comparison of mania and depression
    • Rubin, E., Sackeim, H.A., Prohovnik, I. et al. (1995) Regional cerebral blood flow in mood disorders: IV. Comparison of mania and depression. Psychiatry Res., 61 (1), 1-10.
    • (1995) Psychiatry Res. , vol.61 , Issue.1 , pp. 1-10
    • Rubin, E.1    Sackeim, H.A.2    Prohovnik, I.3
  • 53
    • 18044364021 scopus 로고    scopus 로고
    • Neuropsychological disturbances and cerebral blood flow in bipolar disorder
    • Benabarre, A., Vieta, E., Martínez-Arán, A. et al. (2005) Neuropsychological disturbances and cerebral blood flow in bipolar disorder. Aust. Nz. J. Psychiat., 39 (4), 227-234.
    • (2005) Aust. Nz. J. Psychiat. , vol.39 , Issue.4 , pp. 227-234
    • Benabarre, A.1    Vieta, E.2    Martínez-Arán, A.3
  • 54
    • 0030612625 scopus 로고    scopus 로고
    • Uptake of 99mtc-exametazime shown by single photon emission computed tomography before and after lithium withdrawal in bipolar patients: Associations with mania
    • Goodwin, G.M., Cavanagh, J.T., Glabus, M.F. et al. (1997) Uptake of 99mtc-exametazime shown by single photon emission computed tomography before and after lithium withdrawal in bipolar patients: Associations with mania. Brit. J. Psych., 170, 426-430.
    • (1997) Brit. J. Psych. , vol.170 , pp. 426-430
    • Goodwin, G.M.1    Cavanagh, J.T.2    Glabus, M.F.3
  • 56
    • 0032727203 scopus 로고    scopus 로고
    • Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder
    • Blumberg, H.P., Stern, E., Ricketts, S. et al. (1999) Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder. Am. J. Psychiatry, 156 (12), 1986-1988.
    • (1999) Am. J. Psychiatry , vol.156 , Issue.12 , pp. 1986-1988
    • Blumberg, H.P.1    Stern, E.2    Ricketts, S.3
  • 57
    • 0034563661 scopus 로고    scopus 로고
    • Increased anterior cingulate and caudate activity in bipolar mania
    • Blumberg, H.P., Stern, E., Martinez, D. et al. (2000) Increased anterior cingulate and caudate activity in bipolar mania. Biol. Psychiatry, 48 (11), 1045-1052.
    • (2000) Biol. Psychiatry , vol.48 , Issue.11 , pp. 1045-1052
    • Blumberg, H.P.1    Stern, E.2    Martinez, D.3
  • 58
    • 0035212196 scopus 로고    scopus 로고
    • Decision-Making in mania: A PET study
    • Rubinsztein, J.S., Fletcher, P.C., Rogers, R.D. et al. (2001) Decision-Making in mania: A PET study. Brain, 124 (Pt 12), 2550-2563.
    • (2001) Brain , vol.124 , Issue.PART 12 , pp. 2550-2563
    • Rubinsztein, J.S.1    Fletcher, P.C.2    Rogers, R.D.3
  • 59
    • 43149094446 scopus 로고    scopus 로고
    • Changes in regional cerebral blood flow demonstrated by 99mtc-hmpao SPECT in euthymic bipolar patients
    • Culha, A.F., Osman, O., Dogangün, Y. et al. (2008) Changes in regional cerebral blood flow demonstrated by 99mtc-hmpao SPECT in euthymic bipolar patients. Eur. Arch. Psy. Clin. N., 258 (3), 144-151.
    • (2008) Eur. Arch. Psy. Clin. N. , vol.258 , Issue.3 , pp. 144-151
    • Culha, A.F.1    Osman, O.2    Dogangün, Y.3
  • 60
    • 0032886369 scopus 로고    scopus 로고
    • No evidence for left superior temporal dysfunction in asymptomatic schizophrenia and bipolar disorder. PET study of verbal fluency
    • Dye, S.M., Spence, S.A., Bench, C.J. et al. (1999) No evidence for left superior temporal dysfunction in asymptomatic schizophrenia and bipolar disorder. PET study of verbal fluency. Brit. J. Psych., 175, 367-374.
    • (1999) Brit. J. Psych. , vol.175 , pp. 367-374
    • Dye, S.M.1    Spence, S.A.2    Bench, C.J.3
  • 61
    • 0036164459 scopus 로고    scopus 로고
    • Limbic hyperreactivity in bipolar II disorder
    • Berns, G.S., Martin, M. and Proper, S.M. (2002) Limbic hyperreactivity in bipolar II disorder. Am. J. Psychiatry, 159 (2), 304-306.
    • (2002) Am. J. Psychiatry , vol.159 , Issue.2 , pp. 304-306
    • Berns, G.S.1    Martin, M.2    Proper, S.M.3
  • 62
    • 30944467883 scopus 로고    scopus 로고
    • Impaired recruitment of the dorsolateral prefrontal cortex and hippocampus during encoding in bipolar disorder
    • Deckersbach, T., Dougherty, D.D., Savage, C. et al. (2006) Impaired recruitment of the dorsolateral prefrontal cortex and hippocampus during encoding in bipolar disorder. Biol. Psychiatry, 59 (2), 138-146.
    • (2006) Biol. Psychiatry , vol.59 , Issue.2 , pp. 138-146
    • Deckersbach, T.1    Dougherty, D.D.2    Savage, C.3
  • 63
    • 74349118664 scopus 로고    scopus 로고
    • Resting prefrontal hypometabolism and paralimbic hypermetabolism related to verbal recall deficits in euthymic older adults with bipolar disorder
    • Brooks, J. O. III, Hoblyn, J. C., Woodard, S. A., et al. (2009). Resting prefrontal hypometabolism and paralimbic hypermetabolism related to verbal recall deficits in euthymic older adults with bipolar disorder. American Journal of Geriatric Psychiatry, 17, 1022-1029.
    • (2009) American Journal of Geriatric Psychiatry , vol.17 , pp. 1022-1029
    • Brooks III, J.O.1    Hoblyn, J.C.2    Woodard, S.A.3


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