Methods for the detection of DNA adducts

Methods in Molecular Biology

Volumn 817, Issue , 2012, Pages 207-230

  Brown, Karen ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Accelerator mass spectrometry; Immunoassay; Mass spectrometry; P post labelling

Indexed keywords

MUTAGENIC AGENT; PHOSPHORUS;

ANIMAL; ARTICLE; CHEMISTRY; DNA ADDUCT; GENETICS; HUMAN; IMMUNOASSAY; MASS SPECTROMETRY; METHODOLOGY; MUTAGEN TESTING; SPECTROFLUOROMETRY;

ANIMALS; DNA ADDUCTS; HUMANS; IMMUNOASSAY; MASS SPECTROMETRY; MUTAGENICITY TESTS; MUTAGENS; PHOSPHORUS RADIOISOTOPES; SPECTROMETRY, FLUORESCENCE;

ANIMALIA;

EID: 84855998884     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-421-6_11     Document Type: Article

References (76)

1. Phillips, D. H. (2005) DNA adducts as markers of exposure and cancer risk. Mutat. Res. 577, 284-292. (Pubitemid 41225507)
2. Reddy, M. V. (2000) Methods for testing compounds for DNA adduct formation. Regulatory Toxicol. Pharmacol. 32, 256-263. (Pubitemid 32163698)
3. Poirier, M. C. (2004) Chemical-induced DNA damage and human cancer risk. Nature Reviews Cancer 4, 630-636.
4. Sharma, R. A. and Farmer, P. B. (2004) Biological relevance of adduct detection to the chemoprevention of cancer. Clin. Cancer Res. 10, 4901-4912. (Pubitemid 39099763)
5. Egner, P. A., Groopman, J. D., Wang, J. S., Kensler, T. W. and Friesen, M. D. (2006) Quantification of aflatoxin-B-1-N-7-guanine in human urine by high-performance liquid chromatography and isotope dilution tandem mass spectrometry. Chem. Res. Toxicol. 19, 1191-1195. (Pubitemid 44454035)
6. Turesky, R. J. and Vouros, P. (2004) Formation and analysis of heterocyclic amine-DNA adducts in vitro and in vivo. J. Chromatog. B 802, 155-166. (Pubitemid 38224281)
7. Tang DL, Phillips DH, Stampfer M, Mooney LA, Hsu YZ, Cho S, Tsai WY, Ma J, Cole KJ, Ni She M, Perera FP (2001) Association between carcinogen-DNA adducts in white blood cells and lung cancer risk in the physicians health study. Cancer Res. 62, 6708-6712. (Pubitemid 32896491)
8. Phillips, D. H., Farmer, P. B., Beland, F. A., Nath, R. G., Poirier, M. C. Reddy, M. V. and Turteltaub, K. W. (2000) Methods of DNA adduct determination and their application to testing compounds for genotoxicity. Environ. Mol. Mutagenesis 35, 222-233. (Pubitemid 30196666)
9. 32 P-Labeling test for DNA damage. Proc. Natl. Acad. Sci. USA. 78, 6126-6129.
10. 32 P-postlabeling assay. Carcinogenesis 13, 1053-1074.
11. 32 P-postlabeling assay based on the specific enzymatic conversion of bulky DNA lesions to radiolabeled dinucleotides and nucle-oside 5 ¢-monophosphates. Carcinogenesis 10, 1231-1239. (Pubitemid 19177226)
12. 32 P-postlabelling: evidence for the non-random manifestation of phosphotriester lesions in vivo. Cancer Res. 60, 1276-1282. (Pubitemid 30151995)
13. 32 P-postlabeling assay for DNA adducts. Nature Protocols 2, 2772-2781.
14. 32 P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 7, 1543-1551.
15. 32 P-postlabeling analysis of aromatic carcinogen:DNA adducts. Cancer Res. 25, 5656-5662. (Pubitemid 16218569)
16. 6-methylguanine in DNA from human tissues. Carcinogenesis 13, 469-475.
17. 32 P-Postlabelling method for the detection of 7-alkyguanine adducts formed by reaction of different 1, 2-alkyl epoxides with DNA. Carcinogenesis 16, 483-489.
18. Arlt, V. M., Gingerich, J. Schmeiser, H. H., Phillips, D. H., Douglas, G. R. and White, P. A. (2008) Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in Muta (TM) Mouse and lung epithelial cells derived from Muta (TM) Mouse. Mutagenesis 23, 483-490.
19. 32 P-postlabelled tamoxifen-DNA adducts: a comparison with thin layer chromatography. Carcinogenesis 19, 1061-1069. (Pubitemid 28375402)
20. 32 P-Postlabeling/polyacrylamide gel electrophoresis analysis: Application to the detection of DNA adducts. Chem. Res. Toxicol. 15, 305-311. (Pubitemid 34241367)
21. Pavanello, S., Favretto, D., Brugnone, F., Mastrangelo, G., Dal Pra, G. and Clonfero, E. (1999) HPLC/fluorescence determination of anti-BPDE-DNA adducts in mononuclear white blood cells from PAH-exposed humans. Carcinogenesis 20, 431-435. (Pubitemid 29112631)
22. Weaver, V. M. and Groopman, J. D. (1994) Fluorescence quantification of aflatoxin N 7-guanine adducts. Cancer Epidemiol. Biomarkers Prev. 3, 669-674. (Pubitemid 24377960)
23. Sharma, M. (2000) Analysis of tamoxifen-DNA adducts by high-performance liquid chroma-tography using postcolumn online photochemical activation. Biochem. Biophys. Res. Commun. 273, 40-44. (Pubitemid 30426859)
24. 1, its metabolites, and DNA adducts by synchronous fluorescence spectro-photometry. Cancer Res. 46, 3249-3253. (Pubitemid 16096850)
25. Jang, H. G., Park, M., Wishnok, J. S., Tannenbaum, S. R. and Wogan G. N. (2006) Hydroxyl-specific fluorescence labeling of ABP-deoxyguanosine, PhIP-deoxyguanosine, and AFB1-formamidopyrimidine with BODIPY-FL. Anal. Biochem. 359, 151-160. (Pubitemid 44821043)
26. Borthakur, G., Butryee, C., Stacewicz-Sapuntzakis, M. and Bowen, P. E. (2008) Exfoliated buccal mucosa cells as a source of DNA to study oxidative stress. Cancer Epidemiol. Biomarkers Prev. 17, 212-219. (Pubitemid 351196293)
27. Loft, S., Svoboda, P., Kasai, H., Tjonneland, A., Vogel, U., Moller, P., Overvad, K. and Raaschou-Nielsen, O. (2006) Prospective study of 8-oxo-7, 8-dihydro-2 ¢-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis 27, 1245-1250. (Pubitemid 43985440)
28. Sawa, T., Tatemichi, M., Akaike, T., Barbin, A. and Ohshima, H. (2006) Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chro-matography-electrochemical detection coupled with immunoaffinity purification: Association with cigarette smoking. Free Radical Biology and Medicine 40, 711-720. (Pubitemid 43170823)
29. Poirier, M. C. and Weston, A. (1996) Human DNA adduct measurements: state of the art. Environ. Health Perspectives 104, 883-893. (Pubitemid 26402326)
30. de Koc, T. M. C. M., Moonen, H. J. J., van Delft. J. and van Schooten F. J. (2002) Methodologies for bulky DNA adduct analysis in biomonitoring of environmental and occupational exposures. J. Chromatog. B. 778, 345-355.
31. Manchester, D. K., Weston, A., Choi, J. S., Trivers, G., Fennessey, P. V., Quintana, E., Farmer, P. B., Mann, D. L. and Harris, C. C. (1988) Detection of benzo(a)pyrene diol epox-ide-DNA adducts in human placenta. Proc. Natl. Acad. Sci. USA, 85, 9243-9247. (Pubitemid 19001873)
32. Shuker, D. E. G. and Farmer, P. B. (1992) Relevance of urinary DNA adducts as markers of carcinogen exposure. Crit. Rev Toxicol. 5, 450-460.
33. 4-ethylthymidine in human biomonitoring studies. Chem. Res. Toxicol. 15, 433-437. (Pubitemid 34241383)
34. Santella, R. M. (1999) Immunological methods for detection of carcinogen-DNA damage in humans. Cancer Epidemiol. Biomarkers Prev. 8, 733-739. (Pubitemid 29445009)
35. Leuratti, C., Singh, R., Lagneau, C., Farmer, P. B., Plastaras, J. P., Marnett, L. J. and Shuker, D. E. G. (1998) Determination of malondial-dehyde- induced DNA damage in human tissues using an immunoslot blot assay. Carcinogenesis 19, 1919-1924. (Pubitemid 28521931)
36. Santella, R. M., Weston, A., Perera, F. P., Trivers, G. T., Harris, C. C., Young, T. L., Nguyen, D., Lee, B. M. and Poirier, M. C. (1988) Interlaboratory comparison of antisera and immunoassays for benzo a pyrene-diol-epoxide-I-modified DNA. Carcinogenesis 9, 1265-1269.
37. Divi, R. L., Beland, F. A., Fu, P. F., Von Tungeln, L. S., Schoket, B., Camara, J. E., Ghei, M., Rothman, N., Sinha, R., Poirier, M. C. (2002) Highly sensitive chemiluminescence immunoassay for benzo a pyrene-DNA adducts: validation by comparison with other methods, and use in biomonitoring. Carcinogenesis 23, 2043-2049. (Pubitemid 36104956)
38. 32 P-postlabeling. Cancer Res. 59, 4829-4833. (Pubitemid 29472884)
39. Santella, R. M. (1991) DNA adducts in humans as biomarkers of exposure to environmental and occupational carcinogens. Environ. Cancer Rev. C9, 57-81.
40. Mumford, J. L., Williams, K., Wilcosky, T. C., Everson, R. B., Young, T. L. and Santella, R. M. (1996) A sensitive color ELISA for detecting polycyclic aromatic hydrocarbon-DNA adducts in human tissues. Mutat. Res. 359, 171-177. (Pubitemid 26122141)
41. 1-DNA adducts formed in vivo. Cancer Res. 48, 6328-6331.
42. Wilson, V. L., Weston, A., Manchester, D. K., Trivers, G. E., Roberts, D. W., Kadlubar, F. F., Montesano, R., Willey, J. C., Mann, D. L. and Harris, C. C. (1989) Alkyl and aryl carcinogen adducts detected in human peripheral lung. Carcinogenesis 10, 2149-2153. (Pubitemid 19280500)
43. Sharma, R. A., McLelland, H. R., Hill, K. A., Ireson, C. R., Euden, S. A., Manson, M. M., Pirmohamed, M., Marnett, L. J., Gescher, A. J. and Steward, W. P. (2001) Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Clin. Cancer Res. 7, 1894-1900. (Pubitemid 32994823)
44. Van Gijssel, H. E., Schild, L. J., Watt, D. L., Roth, M. J., Wang, G. Q., Dawsey, S. M., Albert, P. S., Qiao, Y. L., Taylor, P. R., Dong, Z. W. and Poirier, M. C. (2004) Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985. Mutat. Res. 547, 55-62. (Pubitemid 38315072)
45. Rybicki, B. A., Rundle, A., Savera, A. T., Sankey, S. S. and Tang, D. (2004) Polycyclic aromatic hydrocarbon-DNA adducts in prostate cancer. Cancer Res. 64, 8854-8859. (Pubitemid 39665489)
46. Zhang, Y. J., Hsu, T. M. and Santella, R. M. (1995) Immunoperoxidase detection of poly-cyclic aromatic hydrocarbon-DNA adducts in oral mucosa cells of smokers and non-smokers. Cancer Epidemiol. Biomarkers Prev. 4, 133-138.
47. Rundle, A., Tang, D. L., Zhou, J. Z., Cho, S. and Perera, F. (2000) The association between glutathione S-transferase M1 genotype and polycyclic aromatic hydrocarbon-DNA adducts in breast tissue. Cancer Epidemiol. Biomarkers Prev. 9, 1079-1085.
48. Blommaert, F. A., Michael, C., Terheggen, P. M. A. B., Muggia, F. M., Kortes, V., Schornagel, J. H., Hart, A. A. M. and Engelse, L. D. (1993) Drug-induced DNA modification in buccal cells of cancer patients receiving carboplatin and cisplatin combination chemotherapy, as determined by an immunocytochemical method: interindividual variation and correlation with disease response. Cancer Res. 53, 5669-5675. (Pubitemid 23360269)
49. Farmer, P. B., Brown, K., Tompkins, E., Emms, V. L., Jones, D. J. L., Singh, R. and Phillips, D. H. (2005) DNA adducts: mass spectrometry methods and future prospects. Toxicol. Appl. Pharmacol. 207, S293-S301. (Pubitemid 41265528)
50. Ziegel, R., Shallop, A., Jones, R., Tretyakova, N. (2003) K-ras gene sequence effects on the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone (NNK)-DNA adducts. Chem. Res. Toxicol. 16, 541-550. (Pubitemid 36514513)
51. Brown, K.; Harvey, C. A.; Turteltaub, K. W.; Shields, S. J. (2003) Structural characterization of carcinogen-modified oligodeoxynucleotide adducts using matrix-assisted laser desorption/ionization mass spectrometry. J. Mass Spectrom. 38, 68-79. (Pubitemid 36157759)
52. Singh, R. and Farmer, P. B. (2006) Liquid chromatography-electrospray ionization-mass spectrometry: the future of DNA adduct detection. Carcinogenesis 27, 178-196. (Pubitemid 43159870)
53. Koc, H. and Swenberg, J. A. (2002) Applications of mass spectrometry for quantitation of DNA adducts. J. Chromatogr. B. 778, 323-343.
54. Tompkins, E. M., Jones, D. J. L., Lamb, J. H., Marsden, D. A., Farmer, P. B. and Brown, K. (2008) Simultaneous detection of five different 2-hydroxyethyl DNA adducts formed by ethyl-ene oxide exposure, using a high-performance liquid chromatography/electrospray ionisation tandem mass spectrometry assay. Rapid Commun. Mass Spectrom 22, 19-28.
55. Marsden, D. A.; Jones, D. J. L.; Lamb, J. H.; Tompkins, E.; Farmer, P. B.; Brown K. (2007) Determination of endogenous and exogenously derived N 7-(2-hydroxyethyl)guanine adducts in ethylene oxide treated rats. Chem. Res. Toxicol. 20, 290-299. (Pubitemid 46408866)
56. Gamboa da Costa, G., Marques, M. M., Beland, F. A., Freeman, J. P., Churchwell, M. I., Doerge, D. R. (2003) Quantification of tamox-ifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry. Chem. Res. Toxicol. 16, 357-366. (Pubitemid 36373700)
57. Bessette, E. E., Goodenough, A. K., Langouët, S., Yasa, I., Kozekov, I. D., Spivack, S. D., Turesky, R. J. (2009) Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadruple ion trap mass spectrometer. Anal. Chem. 81, 809-819.
58. Kanaly, R. A., Matsui, A., Hanaoka, T. and Matsuda, T. (2007) Application of the adduc-tome approach to assess intertissue DNA damage variations in human lung and esophagus. Mutat. Res. 625, 83-93. (Pubitemid 350016107)
59. Farmer, P. B. and Singh, R. (2008) Use of DNA adducts to identify human health risk from exposure to hazardous environmental pollutants: The increasing role of mass spec-trometry in assessing biologically effective doses of genotoxic carcinogens. Mutat. Res. 659, 68-76.
60. Phillips, D. H., Hewer A. and Osborne, M. R. (1992) Interaction of omeprazole with DNA in rat tissues. Mutagenesis 7, 277-283.
61. Vogel. J. S., Turteltaub, K. W., Finkel, R. and Nelson, D. E. (1995) Accelerator mass spec-trometry. Anal. Chem. 67, 353A-359A.
62. Brown, K., Tompkins, E. M. and White, I. N. H. (2006) Applications of accelerator mass spectrometry for pharmacological and toxico-logical research. Mass Spec. Rev. 25, 127-145.
63. Turteltaub, K. W., Vogel, J. S., Frantz, C. E. and Fultz, E. (1993) Studies on DNA adduction with heterocyclic amines by accelerator mass spectrometry: a new technique for tracing isotope-labelled DNA adduction. In Phillips, D. H., Castegno, M., Bartsch, H., editors. Postlabeling methods for detecting DNA adducts. Lyon: IARC, p 293-391.
64. Turteltaub, K. W., Felton, J. S., Gledhill, B. L., Vogel, J. S., Southon, J. R., Caffee, M. W., Finkel, R. C., Nelson, D. E., Proctor, I. D. and Davis, J. C. (1990). Accelerator mass spec-trometry in biomedical dosimetry: relationship between low-level exposure and covalent binding of heterocyclic amine carcinogens to DNA. Proc Natl Acad Sci USA 87, 5288-5292. (Pubitemid 20260164)
65. Mauthe, R. J., Dingley, K. H., Leveson, S. H., Freeman, S. P., Turesky, R. J., Garner, R. C. and Turteltaub, K. W. (1999). Comparison of DNA-adduct and tissue-available dose levels of MeIQx in human and rodent colon following administration of a very low dose. Int J Cancer 80, 539-545. (Pubitemid 29047518)
66. 14 C-ethylene oxide: evidence for a novel mechanism of endogenous DNA adduct formation. Cancer Res. 69, 3052-3059.
67. Martin, E. A., Brown, K., Gaskell, M., Al-Azzawi, F., Garner, R. C., Boocock, D. J., Mattock, E., Pring, D. W., Dingley, K., Turteltaub, K. W., Smith, L. L. and White, I. N. H. (2003) Tamoxifen DNA damage detected in human endometrium using accelerator mass spectrometry. Cancer Research 63, 8461-8465. (Pubitemid 37549502)
68. Coldwell, K. E., Cutts, S. M., Ognibene, T. J., Henderson, P. T. and Phillips, D. R. (2008) Detection of adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant adriamycin concentrations. Nucl. Acids Res. 36, e100.
69. Mally, A., Zepnik, H., Wanek, P., Eder, E., Dingley, K., Ihmels, H., Volkel, W. and Dekant, W. (2004) Ochratoxin A: lack of formation of covalent DNA adducts. Chem. Res. Toxicol. 17, 234-242. (Pubitemid 38252503)
70. 14 C bio-AMS preparation laboratory. Nucl Instr and Meth B 172, 404-408. (Pubitemid 32067561)
71. Brown, K., Dingley, K. H. and Turteltaub, K. W. (2005) Accelerator Mass Spectrometry for Biomedical Research, in Biological Mass Spectrometry, 402, Methods in Enzymology, 423-443 (Ed. Burlingame, A.). Academic Press. San Diego, California, U.S. (Pubitemid 43053135)
72. 14 C-labeled therapeutic dose. Cancer Res. 67, 6995-7002. (Pubitemid 47105548)
73. 14 C-acetic anhydride and accelerator mass spectrometry. Chem. Biol. Interact. 126, 171-183. (Pubitemid 30336354)
74. 6-methyldeoxyguanosine adducts. Rap. Commun. Mass Spectrom. 20, 883-891. (Pubitemid 43326698)
75. 14 C via accelerator mass spectrometry. Anal. Chem. 75, 2192-2196. (Pubitemid 36542364)
76. 14 C in nonvolatile samples by accelerator mass spectrometry. Anal. Chem. 76, 328-334. (Pubitemid 38090768)