Baseline imaging reveals preexisting retinal abnormalities in mice

Advances in Experimental Medicine and Biology

Volumn 723, Issue , 2012, Pages 459-469

  Bell, Brent A ^a   Kaul, Charles ^a   Rayborn, Mary E ^a   Hollyfield, Joe G ^a  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

Author keywords

Abnormalities; Baseline; Fundus; Imaging; Lesion; Mice; Ophthalmoscope; Optical Coherence Tomography; Retina; Scanning Laser

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EYE PHOTOGRAPHY; HISTOLOGY; IMAGE ANALYSIS; IMAGE DISPLAY; MOUSE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RETINA DISEASE; SCANNING LASER OPHTHALMOSCOPY;

ANIMALS; DISEASE MODELS, ANIMAL; LASERS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; OPHTHALMOSCOPY; RETINA; RETINAL DISEASES; TOMOGRAPHY, OPTICAL COHERENCE;

ANIMALIA; MUS;

EID: 84855959725     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0631-0_58     Document Type: Conference Paper

References (11)

1. Eter N, Engel DR, Meyer L et al (2008) In vivo visualization of dendritic cells, macrophages, and microglial cells responding to laser-induced damage in the fundus of the eye. Invest Ophthalmol Vis Sci 49:3649-3658
2. Fischer MD, Huber G, Beck SC et al (2009) Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography. PLoS One 4:e7507
3. Gabriele ML, Ishikawa H, Schuman JS et al (2010) Reproducibility of Spectral-Domain Optical Coherence Tomography Total Retinal Thickness Measurements in Mice. Invest Ophthalmol Vis Sci
4. Hawes NL, Smith RS, Chang B et al (1999) Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis 5:22
5. Hollyfield JG, Bonilha VL, Rayborn ME et al (2008) Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med 14:194-198 (Pubitemid 351214555)
6. Huber G, Beck SC, Grimm C et al (2009) Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest Ophthalmol Vis Sci 50:5888-5895
7. Kocaoglu OP, Uhlhorn SR, Hernandez E et al (2007) Simultaneous fundus imaging and optical coherence tomography of the mouse retina. Invest Ophthalmol Vis Sci 48:1283-1289 (Pubitemid 351261425)
8. Luhmann UF, Robbie S, Munro PM et al (2009) The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages. Invest Ophthalmol Vis Sci 50:5934-5943
9. Paques M, Guyomard JL, Simonutti M et al (2007) Panretinal, high-resolution color photography of the mouse fundus. Invest Ophthalmol Vis Sci 48:2769-2774 (Pubitemid 351261232)
10. Ruggeri M, Tsechpenakis G, Jiao S et al (2009) Retinal tumor imaging and volume quantification in mouse model using spectral-domain optical coherence tomography. Opt Express 17:4074-4083
11. Xu H, Chen M, Manivannan A et al (2008) Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice. Aging Cell 7:58-68