Reconstruction of 3D stacked hepatocyte tissues using degradable, microporous poly(d,l-lactide-co-glycolide) membranes

Biomaterials

Volumn 33, Issue 9, 2012, Pages 2693-2700

  Kasuya, Junichi ^a   Sudo, Ryo ^a   Tamogami, Ryu ^a   Masuda, Genta ^a   Mitaka, Toshihiro ^b   Ikeda, Mariko ^a   Tanishita, Kazuo ^a  

^a KEIO UNIVERSITY   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Biodegradation; Cell culture; Hepatocyte; Liver; Polyglycolic acid; Polylactic acid

Indexed keywords

CELL POLARITY; CULTURE METHODS; HEPATIC TISSUE; HEPATOCYTES; IMMUNOFLUORESCENT STAINING; IN-VITRO; LIVER-SPECIFIC FUNCTIONS; MICROPOROUS; MULTI-LAYERED; POLY GLYCOLIC ACID; POLY LACTIC ACID; POLY(D ,L-LACTIDE-CO- GLYCOLIDE); STACKED STRUCTURE; THREE-DIMENSIONAL (3D);

BIODEGRADATION; CELL CULTURE; CELLS; HISTOLOGY; LIVER; MONOLAYERS; ORGANIC POLYMERS; SCAFFOLDS (BIOLOGY); TISSUE;

THREE DIMENSIONAL;

POLYGLYCOLIDE; POLYLACTIDE; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIODEGRADATION; CELL CULTURE; CELL POLARITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOFLUORESCENCE TEST; LIVER CELL; LIVER FUNCTION; MALE; MEMBRANE STRUCTURE; NONHUMAN; POROSITY; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CELL ADHESION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SHAPE; CELLS, CULTURED; GENE EXPRESSION REGULATION; HEPATOCYTES; LACTIC ACID; LIVER; MEMBRANES, ARTIFICIAL; MICROSCOPY, ELECTRON, SCANNING; ORGAN SPECIFICITY; POLYGLYCOLIC ACID; POROSITY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84855956929     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.12.039     Document Type: Article

References (28)

1. Landry J., Bernier D., Ouellet C., Goyette R., Marceau N. Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities. JCell Biol 1985, 101:914-923.
2. Koide N., Sakaguchi K., Koide Y., Asano K., Kawaguchi M., Matsushima H., et al. Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged. Exp Cell Res 1990, 186:227-235.
3. Abu-Absi S.F., Friend J.R., Hansen L.K., Hu W.S. Structural polarity and functional bile canaliculi in rat hepatocyte spheroids. Exp Cell Res 2002, 274:56-67.
4. Matsushita T., Ijima H., Koide N., Funatsu K. High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam. Appl Microbiol Biotechnol 1991, 36:324-326.
5. Yamashita Y., Shimada M., Tsujita E., Shirabe K., Ijima H., Nakazawa K., et al. Efficacy of a larger version of the hybrid artificial liver support system using a polyurethane foam/spheroid packed-bed module in a warm ischemic liver failure pig model for preclinical experiments. Cell Transplant 2003, 12:101-107.
6. Gerlach J.C., Schnoy N., Encke J., Smith M.D., Muller C., Neuhaus P. Improved hepatocyte invitro maintenance in a culture model with woven multicompartment capillary systems: electron microscopy studies. Hepatology 1995, 22:546-552.
7. Sakai Y., Naruse K., Nagashima I., Muto T., Suzuki M. Large-scale preparation and function of porcine hepatocyte spheroids. Int J Artif Organs 1996, 19:294-301.
8. Sudo R., Mitaka T., Ikeda M., Tanishita K. Reconstruction of 3D stacked-up structures by rat small hepatocytes on microporous membranes. FASEB J 2005, 19:1695-1697.
9. Hacker M.C., Mikos A.G. Synthetic polymers. Principles of regenerative medicine 2008, 604-635. Academic Press, Massachusetts. A. Atala, R. Lanza, J. Thomson, R. Nerem (Eds.).
10. Goldstein A.S., Zhu G., Morris G.E., Meszlenyi R.K., Mikos A.G. Effect of osteoblastic culture conditions on the structure of poly(DL-lactic-co-glycolic acid) foam scaffolds. Tissue Eng 1999, 5:421-434.
11. Ionescu L.C., Lee G.C., Sennett B.J., Burdick J.A., Mauck R.L. An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering. Biomaterials 2010, 31:4113-4120.
12. Hasirci V., Berthiaume F., Bondre S.P., Gresser J.D., Trantolo D.J., Toner M., et al. Expression of liver-specific functions by rat hepatocytes seeded in treated poly(lactic-co-glycolic) acid biodegradable foams. Tissue Eng 2001, 7:385-394.
13. Mitaka T., Sato F., Mizuguchi T., Yokono T., Mochizuki Y. Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells. Hepatology 1999, 29:111-125.
14. Kasuya J., Sudo R., Mitaka T., Ikeda M., Tanishita K. Hepatic stellate cell-mediated three-dimensional hepatocyte and endothelial cell triculture model. Tissue Eng Part A 2011, 17:361-370.
15. Michalopoulos G.K., Bowen W.C., Zajac V.F., Beer-Stolz D., Watkins S., Kostrubsky V., et al. Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and epidermal growth factor. Hepatology 1999, 29:90-100.
16. Nahmias Y., Schwartz R.E., Hu W.S., Verfaillie C.M., Odde D.J. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue invitro. Tissue Eng 2006, 12:1627-1638.
17. Nakazawa K., Izumi Y., Fukuda J., Yasuda T. Hepatocyte spheroid culture on a polydimethylsiloxane chip having microcavities. JBiomater Sci Polym Ed 2006, 17:859-873.
18. Ranucci C.S., Kumar A., Batra S.P., Moghe P.V. Control of hepatocyte function on collagen foams: sizing matrix pores toward selective induction of 2-D and 3-D cellular morphogenesis. Biomaterials 2000, 21:783-793.
19. Salerno A., Guarnieri D., Iannone M., Zeppetelli S., Netti P.A. Effect of micro- and macroporosity of bone tissue three-dimensional-poly(epsilon-caprolactone) scaffold on human mesenchymal stem cells invasion, proliferation, and differentiation invitro. Tissue Eng Part A 2010, 16:2661-2673.
20. Sudo R., Takahashi N., Mitaka T., Ikeda M., Tanishita K. The effect of micropatterned pores on the formation and movement of small hepatocyte colonies. JBiomech Sci Eng 2008, 3:249-262.
21. Croll T.I., O'Connor A.J., Stevens G.W., Cooper-White J.J. Controllable surface modification of poly(lactic-co-glycolic acid) (PLGA) by hydrolysis or aminolysis I: physical, chemical, and theoretical aspects. Biomacromolecules 2004, 5:463-473.
22. Tan J.L., Tien J., Pirone D.M., Gray D.S., Bhadriraju K., Chen C.S. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc Natl Acad Sci USA 2003, 100:1484-1489.
23. Talamini M.A., Kappus B., Hubbard A. Repolarization of hepatocytes in culture. Hepatology 1997, 25:167-172.
24. Folkman J., Moscona A. Role of cell shape in growth control. Nature 1978, 273:345-349.
25. Ben-Ze'ev A., Robinson G.S., Bucher N.L., Farmer S.R. Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci USA 1988, 85:2161-2165.
26. Mooney D., Hansen L., Vacanti J., Langer R., Farmer S., Ingber D. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. JCell Physiol 1992, 151:497-505.
27. Watt F.M., Jordan P.W., O'Neill C.H. Cell shape controls terminal differentiation of human epidermal keratinocytes. Proc Natl Acad Sci USA 1988, 85:5576-5580.
28. Sudo R., Mitaka T., Ikeda M., Tanishita K. Morphological and functional changes of rat hepatocytes by vertical cell-cell adhesion in three-dimensional stacked-up culture. JBiomech Sci Eng 2008, 3:235-248.