-
2
-
-
0023881950
-
Gastrointestinal stromal tumors. An immunohistochemical study of cellular differentiation
-
Miettinen M. 1988. Gastrointestinal stromal tumors. An immunohistochemical study of cellular differentiation. Am. J. Clin. Pathol. 89:601-10
-
(1988)
Am. J. Clin. Pathol.
, vol.89
, pp. 601-610
-
-
Miettinen, M.1
-
3
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
DOI 10.1126/science.279.5350.577
-
Hirota S, Isozaki K, Moriyama Y, et al. 1998. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 279:577-80 (Pubitemid 28067289)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Tunio, G.M.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
4
-
-
0030846533
-
Stem cell factor and hematopoiesis
-
Broudy VC. 1997. Stem cell factor and hematopoiesis. Blood 90:1345-64 (Pubitemid 27355406)
-
(1997)
Blood
, vol.90
, Issue.4
, pp. 1345-1364
-
-
Broudy, V.C.1
-
5
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
DOI 10.1056/NEJM200104053441404
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al. 2001. Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N. Engl. J. Med. 344:1052-56 (Pubitemid 32267975)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.14
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
Andersson, L.C.4
Tervahartiala, P.5
Tuveson, D.6
Silberman, S.L.7
Capdeville, R.8
Dimitrijevic, S.9
Druker, B.10
Demetri, G.D.11
-
6
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
DOI 10.1056/NEJMoa020461
-
Demetri GD, vonMehren M, Blanke CD, et al. 2002. Efficacy and safety of imatinibmesylate in advanced gastrointestinal stromal tumors. N. Engl. J. Med. 347:472-80 (Pubitemid 34879334)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.7
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
Van Den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
Heinrich, M.C.7
Tuveson, D.A.8
Singer, S.9
Janicek, M.10
Fletcher, J.A.11
Silverman, S.G.12
Silberman, S.L.13
Capdeville, R.14
Kiese, B.15
Peng, B.16
Dimitrijevic, S.17
Druker, B.J.18
Corless, C.19
Fletcher, C.D.M.20
Joensuu, H.21
more..
-
7
-
-
0036846345
-
Management of malignant gastrointestinal stromal tumours
-
DOI 10.1016/S1470-2045(02)00899-9
-
Joensuu H, Fletcher C, Dimitrijevic S, et al. 2002. Management of malignant gastrointestinal stromal tumours. Lancet Oncol. 3:655-64 (Pubitemid 35314908)
-
(2002)
Lancet Oncology
, vol.3
, Issue.11
, pp. 655-664
-
-
Joensuu, H.1
Fletcher, C.2
Dimitrijevic, S.3
Silberman, S.4
Roberts, P.5
Demetri, G.6
-
8
-
-
39349085208
-
Incidence and clinicopathologic features of gastrointestinal stromal tumors A population-based study
-
Mucciarini C, Rossi G, Bertolini F, et al. 2007. Incidence and clinicopathologic features of gastrointestinal stromal tumors. A population-based study. BMC Cancer 7:230
-
(2007)
BMC Cancer
, vol.7
, pp. 230
-
-
Mucciarini, C.1
Rossi, G.2
Bertolini, F.3
-
9
-
-
13444270334
-
Gastrointestinal stromal tumors: The incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era - A population-based study in western Sweden
-
DOI 10.1002/cncr.20862
-
Nilsson B, Bumming P, Meis-Kindblom JM, et al. 2005. Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinibmesylate era-a population-based study in western Sweden. Cancer 103:821-29 (Pubitemid 40216412)
-
(2005)
Cancer
, vol.103
, Issue.4
, pp. 821-829
-
-
Nilsson, B.1
Bumming, P.2
Meis-Kindblom, J.M.3
Oden, A.4
Dortok, A.5
Gustavsson, B.6
Sablinska, K.7
Kindblom, L.-G.8
-
10
-
-
33646119879
-
Trends in incidence and survival of mesenchymal neoplasm of the digestive tract within a defined population of northern Norway
-
Steigen SE, Eide TJ. 2006. Trends in incidence and survival of mesenchymal neoplasm of the digestive tract within a defined population of northern Norway. APMIS 114:192-200
-
(2006)
APMIS
, vol.114
, pp. 192-200
-
-
Steigen, S.E.1
Eide, T.J.2
-
11
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
DOI 10.1126/science.1079666
-
Heinrich MC, Corless CL, Duensing A, et al. 2003. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 299:708-10 (Pubitemid 36159485)
-
(2003)
Science
, vol.299
, Issue.5607
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
McGreevey, L.4
Chen, C.-J.5
Joseph, N.6
Singer, S.7
Griffith, D.J.8
Haley, A.9
Town, A.10
Demetri, G.D.11
Fletcher, C.D.M.12
Fletcher, J.A.13
-
12
-
-
0141486251
-
PDGF receptors as cancer drug targets
-
DOI 10.1016/S1535-6108(03)00089-8, PII S1535610803000898
-
Pietras K, Sjoblom T, Rubin K, et al. 2003. PDGF receptors as cancer drug targets. Cancer Cell 3:439-43 (Pubitemid 38340290)
-
(2003)
Cancer Cell
, vol.3
, Issue.5
, pp. 439-443
-
-
Pietras, K.1
Sjoblom, T.2
Rubin, K.3
Heldin, C.-H.4
Ostman, A.5
-
13
-
-
24944536236
-
Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: A study by the Spanish Group for Sarcoma Research (GEIS)
-
Martin J, Poveda A, Llombart-Bosch A, et al. 2005. Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS). J. Clin. Oncol. 23:6190-98
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6190-6198
-
-
Martin, J.1
Poveda, A.2
Llombart-Bosch, A.3
-
14
-
-
38749149936
-
Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST)
-
DOI 10.1002/cncr.23199
-
DeMatteo RP, Gold JS, Saran L, et al. 2008. Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST). Cancer 112:608-15 (Pubitemid 351186201)
-
(2008)
Cancer
, vol.112
, Issue.3
, pp. 608-615
-
-
DeMatteo, R.P.1
Gold, J.S.2
Saran, L.3
Gonen, M.4
Kui, H.L.5
Maki, R.G.6
Singer, S.7
Besmer, P.8
Brennan, M.F.9
Antonescu, C.R.10
-
15
-
-
33751225088
-
High incidence of microscopic gastrointestinal stromal tumors in the stomach
-
DOI 10.1016/j.humpath.2006.07.002, PII S0046817706004163
-
Kawanowa K, Sakuma Y, Sakurai S, et al. 2006. High incidence of microscopic gastrointestinal stromal tumors in the stomach. Hum. Pathol. 37:1527-35 (Pubitemid 44792229)
-
(2006)
Human Pathology
, vol.37
, Issue.12
, pp. 1527-1535
-
-
Kawanowa, K.1
Sakuma, Y.2
Sakurai, S.3
Hishima, T.4
Iwasaki, Y.5
Saito, K.6
Hosoya, Y.7
Nakajima, T.8
Funata, N.9
-
16
-
-
33845940073
-
Minute Gastric Sclerosing Stromal Tumors (GIST Tumorlets) are common in adults and frequently show c-KIT mutations
-
DOI 10.1097/01.pas.0000213307.05811.f0, PII 0000047820070100000014
-
Agaimy A, Wunsch PH, Hofstaedter F, et al. 2007. Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations. Am. J. Surg. Pathol. 31:113-20 (Pubitemid 46036910)
-
(2007)
American Journal of Surgical Pathology
, vol.31
, Issue.1
, pp. 113-120
-
-
Agaimy, A.1
Wunsch, P.H.2
Hofstaedter, F.3
Blaszyk, H.4
Rummele, P.5
Gaumann, A.6
Dietmaier, W.7
Hartmann, A.8
-
17
-
-
70249090434
-
DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: A study of 1840 cases
-
Miettinen M, Wang ZF, Lasota J. 2009. DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases. Am. J. Surg. Pathol. 33:1401-8
-
(2009)
Am. J. Surg. Pathol.
, vol.33
, pp. 1401-1408
-
-
Miettinen, M.1
Wang, Z.F.2
Lasota, J.3
-
18
-
-
77955817308
-
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
-
Novelli M, Rossi S, Rodriguez-Justo M, et al. 2010. DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours. Histopathology 57:259-70
-
(2010)
Histopathology
, vol.57
, pp. 259-270
-
-
Novelli, M.1
Rossi, S.2
Rodriguez-Justo, M.3
-
19
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
DOI 10.1053/hupa.2002.123545
-
Fletcher CD, Berman JJ, Corless C, et al. 2002. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum. Pathol. 33:459-65 (Pubitemid 34747864)
-
(2002)
Human Pathology
, vol.33
, Issue.5
, pp. 459-465
-
-
Fletcher, C.D.M.1
Berman, J.J.2
Corless, C.3
Gorstein, F.4
Lasota, J.5
Longley B.Jack6
Miettinen, M.7
O'Leary, T.J.8
Remotti, H.9
Rubin, B.P.10
Shmookler, B.11
Sobin, L.H.12
Weiss, S.W.13
-
20
-
-
33750618188
-
Gastrointestinal stromal tumors: Pathology and prognosis at different sites
-
DOI 10.1053/j.semdp.2006.09.001, PII S0740257006001432
-
Miettinen M, Lasota J. 2006. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin. Diagn. Pathol. 23:70-83 (Pubitemid 44692418)
-
(2006)
Seminars in Diagnostic Pathology
, vol.23
, Issue.2
, pp. 70-83
-
-
Miettinen, M.1
Lasota, J.2
-
21
-
-
50649085726
-
Risk stratification of patients diagnosed with gastrointestinal stromal tumor
-
Joensuu H. 2008. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum. Pathol. 39:1411-19
-
(2008)
Hum. Pathol.
, vol.39
, pp. 1411-1419
-
-
Joensuu, H.1
-
22
-
-
71449088757
-
Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumor: A retrospective analysis
-
Gold JS, Gonen M, Gutierrez A, et al. 2009. Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumor: a retrospective analysis. Lancet Oncol. 10:1045-52
-
(2009)
Lancet Oncol.
, vol.10
, pp. 1045-1052
-
-
Gold, J.S.1
Gonen, M.2
Gutierrez, A.3
-
23
-
-
0026598711
-
Prognostic factors influencing survival in gastrointestinal leiomyosarcomas. Implications for surgical management and staging
-
Ng EH, Pollock RE, Munsell MF, et al. 1992. Prognostic factors influencing survival in gastrointestinal leiomyosarcomas. Implications for surgical management and staging. Ann. Surg. 215:68-77
-
(1992)
Ann. Surg.
, vol.215
, pp. 68-77
-
-
Ng, E.H.1
Pollock, R.E.2
Munsell, M.F.3
-
24
-
-
78049483265
-
Pattern of recurrence in patients with ruptured primary gastrointestinal stromal tumour
-
Hohenberger P, Ronellenfitsch U, Oladeji O, et al. 2010. Pattern of recurrence in patients with ruptured primary gastrointestinal stromal tumour. Br. J. Surg. 97:1854-59
-
(2010)
Br. J. Surg.
, vol.97
, pp. 1854-1859
-
-
Hohenberger, P.1
Ronellenfitsch, U.2
Oladeji, O.3
-
25
-
-
0036305274
-
Clinical management of gastrointestinal stromal tumors: Before and after STI-571
-
DOI 10.1053/hupa.2002.124122
-
DeMatteo RP, Heinrich MC, El-Rifai WM, Demetri G. 2002. Clinical management of gastrointestinal stromal tumors: before and after STI-571. Hum. Pathol. 33:466-77 (Pubitemid 34747865)
-
(2002)
Human Pathology
, vol.33
, Issue.5
, pp. 466-477
-
-
Dematteo, R.P.1
Heinrich, M.C.2
El-Rifai, W.M.3
Demetri, G.4
-
26
-
-
58149399145
-
Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary andmetastatic/recurrent operable gastrointestinal stromal tumor (GIST): Early results of RTOG 0132/ACRIN 6665
-
Eisenberg BL, Harris J, Blanke CD, et al. 2009. Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary andmetastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665. J. Surg. Oncol. 99:42-47
-
(2009)
J. Surg. Oncol.
, vol.99
, pp. 42-47
-
-
Eisenberg, B.L.1
Harris, J.2
Blanke, C.D.3
-
27
-
-
39149123549
-
Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT
-
DOI 10.1200/JCO.2007.13.4403
-
Blanke CD, Demetri GD, von Mehren M, et al. 2008. Long-term results from a randomized phase II trial of standard-versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KI T. J. Clin. Oncol. 26:620-25 (Pubitemid 351264357)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 620-625
-
-
Blanke, C.D.1
Demetri, G.D.2
Von Mehren, M.3
Heinrich, M.C.4
Eisenberg, B.5
Fletcher, J.A.6
Corless, C.L.7
Fletcher, C.D.M.8
Roberts, P.J.9
Heinz, D.10
Wehre, E.11
Nikolova, Z.12
Joensuu, H.13
-
28
-
-
33744795769
-
Surgical management of advanced gastrointestinal stromal tumors after treatment with targeted systemic therapy using kinase inhibitors
-
DOI 10.1200/JCO.2005.05.3439
-
Raut CP, Posner M, Desai J, et al. 2006. Surgical management of advanced gastrointestinal stromal tumors after treatment with targeted systemic therapy using kinase inhibitors. J. Clin. Oncol. 24:2325-31 (Pubitemid 46630664)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.15
, pp. 2325-2331
-
-
Raut, C.P.1
Posner, M.2
Desai, J.3
Morgan, J.A.4
George, S.5
Zahrieh, D.6
Fletcher, C.D.M.7
Demetri, G.D.8
Bertagnolli, M.M.9
-
29
-
-
34247610583
-
Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor
-
DOI 10.1097/01.sla.0000236630.93587.59, PII 0000065820070300000003
-
DeMatteo RP, Maki RG, Singer S, et al. 2007. Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor. Ann. Surg. 245:347-52 (Pubitemid 46673128)
-
(2007)
Annals of Surgery
, vol.245
, Issue.3
, pp. 347-352
-
-
DeMatteo, R.P.1
Maki, R.G.2
Singer, S.3
Gonen, M.4
Brennan, M.F.5
Antonescu, C.R.6
-
30
-
-
0034666327
-
Soft tissue leiomyosarcomas and malignant gastrointestinal stromal tumors: Differences in clinical outcome and expression of multidrug resistance proteins
-
Plaat BE, Hollema H, Molenaar WM, et al. 2000. Soft tissue leiomyosarcomas and malignant gastrointestinal stromal tumors: differences in clinical outcome and expression of multidrug resistance proteins. J. Clin. Oncol. 18:3211-20
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3211-3220
-
-
Plaat, B.E.1
Hollema, H.2
Molenaar, W.M.3
-
31
-
-
39149127634
-
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033
-
DOI 10.1200/JCO.2007.13.4452
-
Blanke CD, Rankin C, Demetri GD, et al. 2008. Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J. Clin. Oncol. 26:626-32 (Pubitemid 351264358)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 626-632
-
-
Blanke, C.D.1
Rankin, C.2
Demetri, G.D.3
Ryan, C.W.4
Von Mehren, M.5
Benjamin, R.S.6
Raymond, A.K.7
Bramwell, V.H.C.8
Baker, L.H.9
Maki, R.G.10
Tanaka, M.11
Hecht, J.R.12
Heinrich, M.C.13
Fletcher, C.D.M.14
Crowley, J.J.15
Borden, E.C.16
-
32
-
-
34249085905
-
Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: Proposal of new computed tomography response criteria
-
DOI 10.1200/JCO.2006.07.3049
-
Choi H, Charnsangavej C, Faria SC, et al. 2007. Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria. J. Clin. Oncol. 25:1753-59 (Pubitemid 46797957)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.13
, pp. 1753-1759
-
-
Choi, H.1
Charnsangavej, C.2
Faria, S.C.3
Macapinlac, H.A.4
Burgess, M.A.5
Patel, S.R.6
Chen, L.L.7
Podoloff, D.A.8
Benjamin, R.S.9
-
33
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
-
DOI 10.1200/JCO.2003.04.190
-
Heinrich MC, Corless CL, Demetri GD, et al. 2003. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J. Clin. Oncol. 21:4342-49 (Pubitemid 46621810)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.23
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
Blanke, C.D.4
Von Mehren, M.5
Joensuu, H.6
McGreevey, L.S.7
Chen, C.-J.8
Van Den Abbeele, A.D.9
Druker, B.J.10
Kiese, B.11
Eisenberg, B.12
Roberts, P.J.13
Singer, S.14
Fletcher, C.D.M.15
Silberman, S.16
Dimitrijevic, S.17
Fletcher, J.A.18
-
34
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
DOI 10.1016/S0140-6736(04)17098-0, PII S0140673604170980
-
Verweij J, Casali PG, Zalcberg J, et al. 2004. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 364:1127-34 (Pubitemid 39296599)
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
LeCesne, A.4
Reichardt, P.5
Blay, J.-Y.6
Issels, R.7
Van Oosterom, A.8
Hogendoorn, P.C.W.9
Van Glabbeke, M.10
Bertulli, R.11
Judson, I.12
-
35
-
-
33746401591
-
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
-
DOI 10.1016/j.ejca.2006.01.030, PII S0959804906001754
-
Debiec-Rychter M, Sciot R, Le Cesne A, et al. 2006. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur. J. Cancer 42:1093-103 (Pubitemid 44275331)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.8
, pp. 1093-1103
-
-
Debiec-Rychter, M.1
Sciot, R.2
Le Cesne, A.3
Schlemmer, M.4
Hohenberger, P.5
Van Oosterom, A.T.6
Blay, J.-Y.7
Leyvraz, S.8
Stul, M.9
Casali, P.G.10
Zalcberg, J.11
Verweij, J.12
Van Glabbeke, M.13
Hagemeijer, A.14
Judson, I.15
-
36
-
-
78651082042
-
Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
-
Janeway KA, Kim SY, Lodish M, et al. 2011. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations. Proc. Natl. Acad. Sci. USA 108:314-18
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 314-318
-
-
Janeway, K.A.1
Kim, S.Y.2
Lodish, M.3
-
37
-
-
79959715470
-
SDHA loss-of-function mutations in KIT-PDGFRA wildtype gastrointestinal stromal tumors identified by massively parallel sequencing
-
Pantaleo MA, Astolfi A, Indio V, et al. 2011. SDHA loss-of-function mutations in KIT-PDGFRA wildtype gastrointestinal stromal tumors identified by massively parallel sequencing. J. Natl. Cancer Inst. 103:983-87
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 983-987
-
-
Pantaleo, M.A.1
Astolfi, A.2
Indio, V.3
-
38
-
-
50249152932
-
Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors
-
Agaram NP, Wong GC, Guo T, et al. 2008. Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors. Genes Chromosomes Cancer 47:853-59
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 853-859
-
-
Agaram, N.P.1
Wong, G.C.2
Guo, T.3
-
39
-
-
34047198463
-
Prospective multicentric randomized phase III study of imatinib in patients with advanced gastrointestinal stromal tumors comparing interruption versus continuation of treatment beyond 1 year: The French sarcoma group
-
DOI 10.1200/JCO.2006.09.0183
-
Blay JY, Le Cesne A, Ray-Coquard I, et al. 2007. Prospective multicentric randomized phase III study of imatinib in patients with advanced gastrointestinal stromal tumors comparing interruption versus continuation of treatment beyond 1 year: the French Sarcoma Group. J. Clin. Oncol. 25:1107-13 (Pubitemid 46596763)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.9
, pp. 1107-1113
-
-
Blay, J.-Y.1
Le Cesne, A.2
Ray-Coquard, I.3
Bui, B.4
Duffaud, F.5
Delbaldo, C.6
Adenis, A.7
Viens, P.8
Rios, M.9
Bompas, E.10
Cupissol, D.11
Guillemet, C.12
Kerbrat, P.13
Fayette, J.14
Chabaud, S.15
Berthaud, P.16
Perol, D.17
-
40
-
-
77957341199
-
Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: An open-label multicentre randomised phase 3 trial
-
Le Cesne A, Ray-Coquard I, Bui BN, et al. 2010. Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial. Lancet Oncol. 11:942-49
-
(2010)
Lancet Oncol.
, vol.11
, pp. 942-949
-
-
Le Cesne, A.1
Ray-Coquard, I.2
Bui, B.N.3
-
41
-
-
67650306170
-
Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors
-
Demetri GD, Wang Y, Wehrle E, et al. 2009. Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors. J. Clin. Oncol. 27:3141-47
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3141-3147
-
-
Demetri, G.D.1
Wang, Y.2
Wehrle, E.3
-
42
-
-
33750595859
-
Molecular correlates of imatinib resistance in gastrointestinal stromal tumors
-
DOI 10.1200/JCO.2006.06.2265
-
Heinrich MC, Corless CL, Blanke CD, et al. 2006. Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J. Clin. Oncol. 24:4764-74 (Pubitemid 46630941)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4764-4774
-
-
Heinrich, M.C.1
Corless, C.L.2
Blanke, C.D.3
Demetri, G.D.4
Joensuu, H.5
Roberts, P.J.6
Eisenberg, B.L.7
Von Mehren, M.8
Fletcher, C.D.M.9
Sandau, K.10
McDougall, K.11
Ou, W.-B.12
Chen, C.-J.13
Fletcher, J.A.14
-
43
-
-
33645693156
-
Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate
-
Wardelmann E, Merkelbach-Bruse S, Pauls K, et al. 2006. Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate. Clin. Cancer Res. 12:1743-49
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1743-1749
-
-
Wardelmann, E.1
Merkelbach-Bruse, S.2
Pauls, K.3
-
44
-
-
50249092801
-
Heterogeneity of kinase inhibitor resistance mechanisms in GIS T
-
Liegl B, Kepten I, Le C, et al. 2008. Heterogeneity of kinase inhibitor resistance mechanisms in GIS T. J. Pathol. 216:64-74
-
(2008)
J. Pathol.
, vol.216
, pp. 64-74
-
-
Liegl, B.1
Kepten, I.2
Le, C.3
-
45
-
-
1842579584
-
Serum KIT and KIT ligand levels in patients with gastrointestinal stromal tumors treated with imatinib
-
DOI 10.1182/blood-2003-10-3443
-
Bono P, Krause A, von Mehren M, et al. 2004. Serum KIT and KIT ligand levels in patients with gastrointestinal stromal tumors treated with imatinib. Blood 103:2929-35 (Pubitemid 38451662)
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 2929-2935
-
-
Bono, P.1
Krause, A.2
Von Mehren, M.3
Heinrich, M.C.4
Blanke, C.D.5
Dimitrijevic, S.6
Demetri, G.D.7
Joensuu, H.8
-
46
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
DOI 10.1016/S0140-6736(06)69446-4, PII S0140673606694464
-
Demetri GD, van Oosterom AT, Garrett CR, et al. 2006. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 368:1329-38 (Pubitemid 44528723)
-
(2006)
Lancet
, vol.368
, Issue.9544
, pp. 1329-1338
-
-
Demetri, G.D.1
Van Oosterom, A.T.2
Garrett, C.R.3
Blackstein, M.E.4
Shah, M.H.5
Verweij, J.6
McArthur, G.7
Judson, I.R.8
Heinrich, M.C.9
Morgan, J.A.10
Desai, J.11
Fletcher, C.D.12
George, S.13
Bello, C.L.14
Huang, X.15
Baum, C.M.16
Casali, P.G.17
-
47
-
-
37849009384
-
Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate
-
Joensuu H, De Braud F, Coco P, et al. 2008. Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate. Ann. Oncol. 19:173-77
-
(2008)
Ann. Oncol.
, vol.19
, pp. 173-177
-
-
Joensuu, H.1
De Braud, F.2
Coco, P.3
-
48
-
-
68949174991
-
Nilotinib in the treatment of advanced gastrointestinal stromal tumours resistant to both imatinib and sunitinib
-
Montemurro M, Schoffski P, Reichardt P, et al. 2009. Nilotinib in the treatment of advanced gastrointestinal stromal tumours resistant to both imatinib and sunitinib. Eur. J. Cancer 45:2293-97
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 2293-2297
-
-
Montemurro, M.1
Schoffski, P.2
Reichardt, P.3
-
49
-
-
77951878436
-
Phase II study of oral masitinibmesilate in imatinib-naive patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST)
-
Le Cesne A, Blay JY, Bui BN, et al. 2010. Phase II study of oral masitinibmesilate in imatinib-naive patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST). Eur. J. Cancer 46:1344-51
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 1344-1351
-
-
Le Cesne, A.1
Blay, J.Y.2
Bui, B.N.3
-
50
-
-
62849096370
-
Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: A randomised, double-blind, placebo-controlled trial
-
DeMatteo RP, Ballman KV, Antonescu CR, et al. 2009. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet 373:1097-104
-
(2009)
Lancet
, vol.373
, pp. 1097-104
-
-
Dematteo, R.P.1
Ballman, K.V.2
Antonescu, C.R.3
-
51
-
-
78649673624
-
Relation of tumor pathologic and molecular features to outcome after surgical resection of localized gastrointestinal stromal tumor (GIST): Results of the intergroup phase III trial ACOSOG Z9001
-
Corless C, Ballman KV, Antonescu CR, et al. 2010. Relation of tumor pathologic and molecular features to outcome after surgical resection of localized gastrointestinal stromal tumor (GIST): results of the intergroup phase III trial ACOSOG Z9001. J. Clin. Oncol. 28:15s
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Corless, C.1
Ballman, K.V.2
Antonescu, C.R.3
-
52
-
-
77956146147
-
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors
-
Bardsley MR, Horvath VJ, Asuzu DT, et al. 2010. Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. Gastroenterology 139:942-52
-
(2010)
Gastroenterology
, vol.139
, pp. 942-952
-
-
Bardsley, M.R.1
Horvath, V.J.2
Asuzu, D.T.3
-
53
-
-
77957367410
-
Imatinib treatment of metastatic GIST: Don't stop (believing)
-
Heinrich MC. 2010. Imatinib treatment of metastatic GIST: don't stop (believing). Lancet Oncol 11:910-11
-
(2010)
Lancet Oncol
, vol.11
, pp. 910-911
-
-
Heinrich, M.C.1
-
54
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
-
Mahon FX, Rea D, Guilhot J, et al. 2010. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol. 11:1029-35
-
(2010)
Lancet Oncol.
, vol.11
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
|