Increased plasma levels of NGAL, a marker of neutrophil activation, in patients with abdominal aortic aneurysm

Atherosclerosis

Volumn 220, Issue 2, 2012, Pages 552-556

  Ramos Mozo, Priscila ^a   Madrigal Matute, Julio ^a   Vega de Ceniga, Melina ^b   Blanco Colio, Luis Miguel ^a   Meilhac, Olivier ^c   Feldman, Laurent ^c   Michel, Jean Baptiste ^c   Clancy, Paula ^d   Golledge, Jonathan ^d   Norman, Paul E ^e   Egido, Jesus ^a   Martin Ventura, José Luis ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL DE GALDAKAO   (Spain)

^c INSERM   (France)

^d JAMES COOK UNIVERSITY   (Australia)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Abdominal aortic aneurysm; Biomarkers; Intraluminal thrombus; Neutrophil gelatinase associated lipocalin; Polymorphonuclear neutrophils

Indexed keywords

ANTIPLASMIN; D DIMER; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PLASMIN;

ABDOMINAL AORTA ANEURYSM; AORTA MEDIA; ARTICLE; AUSTRALIA; BLOOD VESSEL BIOPSY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PRIORITY JOURNAL; SPAIN; THROMBUS; WESTERN BLOTTING;

ACUTE-PHASE PROTEINS; AORTIC ANEURYSM, ABDOMINAL; AUSTRALIA; BIOLOGICAL MARKERS; BIOPSY; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FRANCE; HUMANS; LINEAR MODELS; LIPOCALINS; MALE; MULTIVARIATE ANALYSIS; NEUTROPHIL ACTIVATION; NEUTROPHILS; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SPAIN; THROMBOSIS; UP-REGULATION;

EID: 84855917316     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.11.023     Document Type: Article

References (29)

1. Sakalihasan N., Limet R., Defawe O.D. Abdominal aortic aneurysm. Lancet 2005, 365:1577-1589.
2. Swedenborg J., Eriksson P. The intraluminal thrombus as a source of proteolytic activity. Ann N Y Acad Sci 2006, 1085:133-138.
3. Michel J.B., Martin-Ventura J.L., Egido J., et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res 2011, 90:18-27.
4. Thompson R.W., Geraghty P.J., Lee J.K. Abdominal aortic aneurysms: basic mechanisms and clinical implications. Curr Probl Surg 2002, 39:110-230.
5. Michel J.B., Thaunat O., Houard X., Meilhac O., Caligiuri G., Nicoletti A. Topological determinants and consequences of adventitial responses to arterial wall injury. Arterioscler Thromb Vasc Biol 2007, 27:1259-1268.
6. Hannawa K.K., Eliason J.L., Woodrum D.T., et al. L-selectin-mediated neutrophil recruitment in experimental rodent aneurysm formation. Circulation 2005, 112:241-247.
7. Eliason J.L., Hannawa K.K., Ailawadi G., et al. Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation. Circulation 2005, 112:232-324.
8. Lindeman J.H., Abdul-Hussien H., van Bockel J.H., Wolterbeek R., Kleemann R. Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells. Circulation 2009, 119:2209-2216.
9. Kjeldsen L., Johnsen A.H., Sengelov H., Borregaard N. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J Biol Chem 1993, 268:10425-10432.
10. Kjeldsen L., Cowland J.B., Borregaard N. Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim Biophys Acta 2000, 1482:272-283.
11. Elneihoum A.M., Falke P., Hedblad B., Lindgarde F., Ohlsson K. Leukocyte activation in atherosclerosis: correlation with risk factors. Atherosclerosis 1997, 131:79-84.
12. Zografos T., Haliassos A., Korovesis S., Giazitzoglou E., Voridis E., Katritsis D. Association of neutrophil gelatinase-associated lipocalin with the severity of coronary artery disease. Am J Cardiol 2009, 104:917-920.
13. Yndestad A., Landrø L., Ueland T., et al. Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. Eur Heart J 2009, 30:1229-1236.
14. Giaginis C., Zira A., Katsargyris A., Klonaris C., Theocharis S. Clinical implication of plasma neutrophil gelatinase-associated lipocalin (NGAL) concentrations in patients with advanced carotid atherosclerosis. Clin Chem Lab Med 2010, 48:1035-1041.
15. Folkesson M., Kazi M., Zhu C., et al. Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms. Thromb Haemost 2007, 98:427-433.
16. Caligiuri G., Rossignol P., Julia P., et al. Reduced immunoregulatory CD31+ T cells in patients with atherosclerotic abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 2006, 26:618-623.
17. Norman P.E., Flicker L., Almeida O.P., Hankey G.J., Hyde Z., Jamrozik K. Cohort profile the health in men study (HIMS). Int J Epidemiol 2009, 38:48-52.
18. Ferguson C.D., Clancy P., Bourke B., et al. Association of statin prescription with small abdominal aortic aneurysm progression. Am Heart J 2010, 159:307-313.
19. Martinez-Pinna R., Lindholt J.S., Blanco-Colio L.M., et al. Increased levels of thioredoxin in patients with abdominal aortic aneurysms (AAAs). A potential link of oxidative stress with AAA evolution. Atherosclerosis 2010, 212:333-338.
20. Falke P., Elneihoum A.M., Ohlsson K. Leukocyte activation: relation to cardiovascular mortality after cerebrovascular ischemia. Cerebrovasc Dis 2000, 10:97-101.
21. Paulsson J., Dadfar E., Held C., Jacobson S.H., Lundahl J. Activation of peripheral and in vivo transmigrated neutrophils in patients with stable coronary artery disease. Atherosclerosis 2007, 192:328-334.
22. Houard X., Touat Z., Ollivier V., et al. Mediators of neutrophil recruitment in human abdominal aortic aneurysms. Cardiovasc Res 2009, 82:532-541.
23. Delbosc S., Alsac J.M., Journe C., et al. Porphyromonas gingivalis participates in pathogenesis of human abdominal aortic aneurysm by neutrophil activation. proof of concept in rats. PLoS One 2011, 6:e18679.
24. Houard X., Rouzet F., Touat Z., et al. Topology of the fibrinolytic system within the mural thrombus of human abdominal aortic aneurysms. J Pathol 2007, 212:20-28.
25. Kjeldsen L., Sengeløv H., Lollike K., Nielsen M.H., Borregaard N. Isolation and characterization of gelatinase granules from human neutrophils. Blood 1994, 83:1640-1649.
26. Kolkenbrock H., Hecker-Kia A., Orgel D., Ulbrich N., Will H. Activation of progelatinase A and progelatinase A/TIMP-2 complex by membrane type 2-matrix metalloproteinase. Biol Chem 1997, 378:71-76.
27. Flo T.H., Smith K.D., Sato S., et al. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 2004, 432:917-921.
28. Haase M., Bellomo R., Devarajan P., Schlattmann P., Haase-Fielitz A. Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009, 54:1012-1024. NGAL Meta-analysis Investigator Group.
29. Vega de Céniga M., Gómez R., Estallo L., Rodríguez L., Baquer M., Barba A. Growth rate and associated factors in small abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 2006, 31:231-236.