Impact of a collagen matrix on early healing, aesthetics and patient morbidity in oral mucosal wounds - A randomized study in humans

Journal of Clinical Periodontology

Volumn 39, Issue 2, 2012, Pages 157-165

  Thoma, Daniel S ^a   Sancho Puchades, Manuel ^a   Ettlin, Dominik A ^a   Hämmerle, Christoph H F ^a   Jung, Ronald E ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

collagen matrix; keratinized tissue; soft tissue augmentation; substitute; transplant; wound healing

Indexed keywords

EID: 84855901130     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2011.01823.x     Document Type: Article

References (32)

1. Bengazi, F., Wennstrom, J. L., &, Lekholm, U., (1996) Recession of the soft tissue margin at oral implants. A 2-year longitudinal prospective study. Clinical Oral Implants Research 7, 303-310. (Pubitemid 126670545)
2. Bouri, A. Jr, Bissada, N., Al-Zahrani, M. S., Faddoul, F., &, Nouneh, I., (2008) Width of keratinized gingiva and the health status of the supporting tissues around dental implants. International Journal of Oral & Maxillofacial Implants 23, 323-326.
3. Farnoush, A., (1978) Techniques for the protection and coverage of the donor sites in free soft tissue grafts. Journal of Periodontology 49, 403-405. (Pubitemid 9015389)
4. Friedmann, A., Strietzel, F. P., Maretzki, B., Pitaru, S., &, Bernimoulin, J. P., (2002) Histological assessment of augmented jaw bone utilizing a new collagen barrier membrane compared to a standard barrier membrane to protect a granular bone substitute material. Clinical Oral Implants Research 13, 587-594. (Pubitemid 41749845)
5. Griffin, T. J., Cheung, W. S., Zavras, A. I., &, Damoulis, P. D., (2006) Postoperative complications following gingival augmentation procedures. Journal of Periodontology 77, 2070-2079. (Pubitemid 46002088)
6. Hammerle, C. H., &, Jung, R. E., (2003) Bone augmentation by means of barrier membranes. Periodontology 2000 33, 36-53. (Pubitemid 37492913)
7. Hammerle, C. H., &, Karring, T., (1998) Guided bone regeneration at oral implant sites. Periodontology 2000 17, 151-175. (Pubitemid 128556026)
8. Hammerle, C. H., &, Lang, N. P., (2001) Single stage surgery combining transmucosal implant placement with guided bone regeneration and bioresorbable materials. Clinical Oral Implants Research 12, 9-18. (Pubitemid 33723208)
9. Jung, R. E., Hurzeler, M. B., Thoma, D. S., Khraisat, A., &, Hammerle, C. H., (2011) Local tolerance and efficiency of two prototype collagen matrices to increase the width of keratinized tissue. Journal of Clinical Periodontology 38, 173-179.
10. Jung, R. E., Siegenthaler, D. W., &, Hammerle, C. H., (2004) Postextraction tissue management: a soft tissue punch technique. International Journal of Periodontics and Restorative Dentistry 24, 545-553. (Pubitemid 39524500)
11. Karring, T., Lang, N. P., &, Loe, H., (1975) The role of gingival connective tissue in determining epithelial differentiation. Journal of Periodontal Research 10, 1-11.
12. Karring, T., Ostergaard, E., &, Loe, H., (1971) Conservation of tissue specificity after heterotopic transplantation of gingiva and alveolar mucosa. Journal of Periodontal Research 6, 282-293.
13. Klinger, A., Asad, R., Shapira, L., &, Zubery, Y., (2010) In vivo degradation of collagen barrier membranes exposed to the oral cavity. Clinical Oral Implants Research 8, 873-876.
14. McGuire, M. K., &, Nunn, M. E., (2005) Evaluation of the safety and efficacy of periodontal applications of a living tissue-engineered human fibroblast-derived dermal substitute. I. Comparison to the gingival autograft: a randomized controlled pilot study. Journal of Periodontology 76, 867-880. (Pubitemid 40903827)
15. McGuire, M. K., Scheyer, E. T., Nunn, M. E., &, Lavin, P. T., (2008) A pilot study to evaluate a tissue-engineered bilayered cell therapy as an alternative to tissue from the palate. Journal of Periodontology 79, 1847-1856.
16. Megias-Alguacil, D., Keller, T., Lutz, K., Barlow, A. P., &, Ettlin, D. A., (2008) Design and construction of a magnetic resonance compatible multi-injector gas jet delivery system. Review of Scientific Instruments 79, 014301.
17. Oh, T. J., Meraw, S. J., Lee, E. J., Giannobile, W. V., &, Wang, H. L., (2003) Comparative analysis of collagen membranes for the treatment of implant dehiscence defects. Clinical Oral Implants Research 14, 80-90. (Pubitemid 37490594)
18. Orsini, M., Orsini, G., Benlloch, D., Aranda, J. J., Lazaro, P., &, Sanz, M., (2004) Esthetic and dimensional evaluation of free connective tissue grafts in prosthetically treated patients: a 1-year clinical study. Journal of Periodontology 75, 470-477. (Pubitemid 38461130)
19. Rossmann, J. A., &, Rees, T. D., (1999) A comparative evaluation of hemostatic agents in the management of soft tissue graft donor site bleeding. Journal of Periodontoloy 70, 1369-1375.
20. Sanz, M., Lorenzo, R., Aranda, J. J., Martin, C., &, Orsini, M., (2009) Clinical evaluation of a new collagen matrix (Mucograft prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial. Journal of Clinical Periodontology 36, 868-876.
21. Schrott, A. R., Jimenez, M., Hwang, J. W., Fiorellini, J., &, Weber, H. P., (2009) Five-year evaluation of the influence of keratinized mucosa on peri-implant soft-tissue health and stability around implants supporting full-arch mandibular fixed prostheses. Clinical Oral Implants Research 20, 1170-1177.
22. Schwarz, F., Rothamel, D., Herten, M., Sager, M., &, Becker, J., (2006) Angiogenesis pattern of native and cross-linked collagen membranes: an immunohistochemical study in the rat. Clinical Oral Implants Research 17, 403-409. (Pubitemid 44114705)
23. Seibert, J. S., (1983) Reconstruction of deformed, partially edentulous ridges, using full thickness onlay grafts. Part I. Technique and wound healing. Compendium of Continuing Education in Dentistry 4, 437-453.
24. Siar, C. H., Toh, C. G., Romanos, G., &, Ng, K. H., (2011) Subcutaneous reactions and degradation characteristics of collagenous and noncollagenous membranes in a macaque model. Clinical Oral Implants Research 22, 113-120.
25. Slade, G. D., &, Spencer, A. J., (1994) Development and evaluation of the Oral Health Impact Profile. Community Dental Health 11, 3-11.
26. Soileau, K. M., &, Brannon, R. B., (2006) A histologic evaluation of various stages of palatal healing following subepithelial connective tissue grafting procedures: a comparison of eight cases. Journal of Periodontology 77, 1267-1273. (Pubitemid 44725036)
27. Tal, H., Kozlovsky, A., Artzi, Z., Nemcovsky, C. E., &, Moses, O., (2008) Cross-linked and non-cross-linked collagen barrier membranes disintegrate following surgical exposure to the oral environment: a histological study in the cat. Clinical Oral Implants Research 19, 760-766.
28. Thoma, D. S., Benic, G. I., Zwahlen, M., Hammerle, C. H., &, Jung, R. E., (2009) A systematic review assessing soft tissue augmentation techniques. Clinical Oral Implants Research 20 (Suppl. 4), 146-165.
29. Thoma, D. S., Subramani, K., Weber, F. E., Luder, H. U., Hämmerle, C. H. F., &, Jung, R. E., (2011) Biodegradation, soft and hard tissue integration of various polyethylene glycol hydrogels: A histomorphometric study in rabbits. Clinical Oral Implants Research 22, 1247-1254.
30. Wei, P. C., Laurell, L., Geivelis, M., Lingen, M. W., &, Maddalozzo, D., (2000) Acellular dermal matrix allografts to achieve increased attached gingiva. Part 1. A clinical study. Journal of Periodontology 71, 1297-1305.
31. Wennstrom, J. L., Bengazi, F., &, Lekholm, U., (1994) The influence of the masticatory mucosa on the peri-implant soft tissue condition. Clinical Oral Implants Research 5, 1-8.
32. Zigdon, H., &, Machtei, E. E., (2008) The dimensions of keratinized mucosa around implants affect clinical and immunological parameters. Clinical Oral Implants Research 19, 387-392.