Early endothelial progenitor cells in bone marrow are a biomarker of cell therapy success in patients with critical limb ischemia

Cytotherapy

Volumn 14, Issue 2, 2012, Pages 232-239

  Smadja, David M ^a,b,c,d   Duong Van Huyen, Jean Paul ^a,c   Dal Cortivo, Liliane ^a,e   Blanchard, Anne ^a,c   Bruneval, Patrick ^a,c   Emmerich, Joseph ^a,b,c   Gaussem, Pascale ^a,c  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Bone marrow mononuclear cells; Cell therapy; Colony forming unitendothelial cells; Critical limb ischemia; Endothelial progenitor cells

Indexed keywords

BIOLOGICAL MARKER; CD34 ANTIBODY;

ADULT; AGED; AMPUTATION; ANGIOGENESIS; ARTICLE; BONE MARROW CELL; CELL COUNT; CELL THERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CRITICAL LIMB ISCHEMIA; ENDOTHELIAL PROGENITOR CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMB ISCHEMIA; METATARSAL BONE; MONONUCLEAR CELL; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; TOE;

EID: 84855891796     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653249.2011.627917     Document Type: Article

References (44)

1. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997;275:964-7. (Pubitemid 27087709)
2. Smadja DM, Cornet A, Emmerich J, Aiach M, Gaussem P. Endothelial progenitor cells: characterization, in vitro expansion, and prospects for autologous cell therapy. Cell Biol Toxicol. 2007;23:223-39. (Pubitemid 46474922)
3. Cannon RO 3rd, Dunbar CE. BM-derived cell therapies for cardiovascular disease. Cytotherapy. 2007;9:305-15. (Pubitemid 46994539)
4. Mund JA, Ingram DA, Yoder MC, Case J. Endothelial progenitor cells and cardiovascular cell-based therapies. Cyto-therapy. 2009;11:103-13.
5. Fadini GP, Agostini C, Avogaro A. Autologous stem cell therapy for peripheral arterial disease meta-analysis and systematic review of the literature. Atherosclerosis. 2010;209:10-7.
6. Hur J, Yoon CH, Kim HS, Choi JH, Kang HJ, Hwang KK, et al. Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler Thromb Vasc Biol. 2004;24:288-93. (Pubitemid 38197580)
7. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med. 2003;348:593-600. (Pubitemid 36204953)
8. Hur J, Yang HM, Yoon CH, Lee CS, Park KW, Kim JH, et al. Identification of a novel role of T cells in postnatal vasculo-genesis: characterization of endothelial progenitor cell colonies. Circulation. 2007;116:1671-82. (Pubitemid 47537841)
9. Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res. 2001;89:E1-7.
10. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med. 2005;353:999-1007. (Pubitemid 41262334)
11. Smadja DM, Godier A, Susen S, Packard RR, Fabiani JN, Aiach M, et al. Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery. Thromb Haemost. 2009;101:983-5.
12. Yoder MC, Mead LE, Prater D, Krier TR, Mroueh KN, Li F, et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood. 2007;109:1801-9. (Pubitemid 46348173)
13. Huang L, Critser PJ, Grimes BR, Yoder MC. Human umbilical cord blood plasma can replace fetal bovine serum for in vitro expansion of functional human endothelial colony-forming cells. Cytotherapy. 2011;13:712-21.
14. Guven H, Shepherd RM, Bach RG, Capoccia BJ, Link DC. The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically signifi-cant coronary artery disease. J Am Coll Cardiol. 2006;48: 1579-87. (Pubitemid 44528190)
15. Massa M, Campanelli R, Bonetti E, Ferrario M, Marinoni B, Rosti V. Rapid and large increase of the frequency of circulating endothelial colony-forming cells (ECFCs) generating late outgrowth endothelial cells in patients with acute myocardial infarction. Exp Hematol. 2009;37:8-9.
16. Smadja DM, Mauge L, Gaussem P, d'Audigier C, Israel-Biet D, Celermajer DS, et al. Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension. Angiogenesis. 2011; 14:17-27.
17. Toshner M, Voswinckel R, Southwood M, Al-Lamki R, Howard LS, Marchesan D, et al. Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2009;180:780-7.
18. Sandri M, Adams V, Gielen S, Linke A, Lenk K, Krankel N, et al. Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 randomized studies. Circulation. 2005;111:3391-9. (Pubitemid 40923392)
19. Shaffer RG, Greene S, Arshi A, Supple G, Bantly A, Moore JS, et al. Effect of acute exercise on endothelial progenitor cells in patients with peripheral arterial disease. Vasc Med. 2006;11:219-26. (Pubitemid 46470499)
20. Fadini GP, Sartore S, Albiero M, Baesso I, Murphy E, Menegolo M, et al. Number and function of endothelial progenitor cells as a marker of severity for diabetic vascu-lopathy. Arterioscler Thromb Vasc Biol. 2006;26:2140-6. (Pubitemid 44253800)
21. Delva P, De Marchi S, Prior M, Degan M, Lechi A, Trettene M, et al. Endothelial progenitor cells in patients with severe peripheral arterial disease. Endothelium. 2008;15:246-53.
22. Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H, et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet. 2002;360:427-35.
23. Duong-Van-Huyen JP, Smadja DM, Bruneval P, Gaussem P, Dal-Cortivo L, Julia P, et al. Bone marrow-derived mononu-clear cell therapy induces distal angiogenesis after local injection in critical leg ischemia. Mod Pathol. 2008;21:837-46. (Pubitemid 351896658)
24. Heeschen C, Lehmann R, Honold J, Assmus B, Aicher A, Walter DH, et al. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation. 2004; 109:1615-22. (Pubitemid 38451717)
25. Smadja DM, Bieche I, Silvestre JS, Germain S, Cornet A, Laurendeau I, et al. Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis. Arterioscler Thromb Vasc Biol. 2008;28:2137-43.
26. Smadja DM, d'Audigier C, Bieche I, Evrard S, Mauge L, Dias JV, et al. Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties. Arterioscler Thromb Vasc Biol. 2011; 31:551-9.
27. Hansen S, Grabau DA, Sorensen FB, Bak M, Vach W, Rose C. The prognostic value of angiogenesis by Chalkley counting in a confirmatory study design on 836 breast cancer patients. Clin Cancer Res. 2000;6:139-46. (Pubitemid 30064986)
28. Beaujean F, Hartmann O, Kuentz M, Le Forestier C, Divine M, Duedari N. A simple, efficient washing procedure for cryopreserved human hematopoietic stem cells prior to reinfusion. Bone Marrow Transplant. 1991;8:291-4.
29. Preti RA, Ahmed T, Ayello J, Helson L, Argani I, Wuest D, et al. Hemopoietic stem cell processing: comparison of progenitor cell recovery using the Cobe 2991 cell washer and the Haemonetics V50 apheresis system. Bone Marrow Transplant. 1992;9:377-81.
30. Six EM, Bonhomme D, Monteiro M, Beldjord K, Jurkowska M, Cordier-Garcia C, et al. A human postnatal lymphoid progenitor capable of circulating and seeding the thymus. J Exp Med. 2007;204:3085-93.
31. Purhonen S, Palm J, Rossi D, Kaskenpaa N, Rajantie I, Yla-Herttuala S, et al. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothe-lium and are not needed for tumor growth. Proc Natl Acad Sci USA. 2008;105:6620-5. (Pubitemid 351754556)
32. Dudley AC, Udagawa T, Melero-Martin JM, Shih SC, Curatolo A, Moses MA, et al. Bone marrow is a reservoir for proangiogenic myelomonocytic cells but not endothelial cells in spontaneous tumors. Blood. 2010;116:3367-71.
33. Urbich C, Aicher A, Heeschen C, Dernbach E, Hofmann WK, Zeiher AM, et al. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J Mol Cell Cardiol. 2005;39:733-42. (Pubitemid 41464410)
34. Ingram DA, Mead LE, Moore DB, Woodard W, Fenoglio A, Yoder MC. Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood. 2005;105:2783-6. (Pubitemid 40446270)
35. Walter DH, Krankenberg H, Balzer JO, Kalka C, Baumgartner I, Schluter M, et al. Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA). Circ Cardiovasc Interv. 2011;4:26-37.
36. Hiatt WR, Baumgartner II, Van Belle E, Driver VR, Norgren L, Belch JJ. NV1FGF gene therapy on amputation-free survival in critical limb ischemia-phase 3 randomized doubleblind placebo-controlled trial. Late-Breaking Clinical Trials, Abstracts AHA 2010 21790. Circulation. 2010.
37. Dudek AZ. Endothelial lineage cell as a vehicle for systemic delivery of cancer gene therapy. Transl Res. 2010;156:136-46.
38. Marboeuf P, Corseaux D, Mouquet F, Van Belle E, Jude B, Susen S. Infl ammation triggers colony forming endothelial cell mobilization after angioplasty in chronic lower limb ischemia. J Thromb Haemost. 2008;6:195-7.
39. Ingram DA, Mead LE, Tanaka H, Meade V, Fenoglio A, Mortell K, et al. Identification of a novel hierarchy of endothe-lial progenitor cells using human peripheral and umbilical cord blood. Blood. 2004;104:2752-60. (Pubitemid 39434958)
40. Au P, Daheron LM, Duda DG, Cohen KS, Tyrrell JA, Lanning RM, et al. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008;111:1302-5. (Pubitemid 351213415)
41. Vanneaux V, El-Ayoubi F, Delmau C, Driancourt C, Lecourt S, Grelier A, et al. In vitro and in vivo analysis of endothelial progenitor cells from cryopreserved umbilical cord blood: are we ready for clinical application? Cell Transplant. 2010;19: 1143-55.
42. Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, et al. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 2011;117:4773-7.
43. Kim SW, Han H, Chae GT, Lee SH, Bo S, Yoon JH, et al. Successful stem cell therapy using umbilical cord blood-derived multipotent stem cells for Buerger's disease and ischemic limb disease animal model. Stem Cells. 2006;24:1620-6. (Pubitemid 44464680)
44. Melero-Martin JM, De Obaldia ME, Kang SY, Khan ZA, Yuan L, Oettgen P, et al. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res. 2008;103: 194-202.