Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males

Neuropsychopharmacology

Volumn 37, Issue 3, 2012, Pages 669-676

  Xie, Pingxing ^a   Kranzler, Henry R ^b   Zhang, Huiping ^a   Oslin, David ^b   Anton, Raymond F ^c   Farrer, Lindsay A ^d   Gelernter, Joel ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

childhood adversity; CHRNA5; Fagerstrom test for nicotine dependence score; gene environment interaction; nicotine dependence

Indexed keywords

NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA5; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHILDHOOD; EUROPEAN AMERICAN; FEMALE; GENETIC ASSOCIATION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; SEX DIFFERENCE; TOBACCO DEPENDENCE;

ADULT; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LIFE CHANGE EVENTS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; RECEPTORS, NICOTINIC; SEX FACTORS; TOBACCO USE DISORDER;

EID: 84855881844     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.240     Document Type: Article

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