Development of a gas chromatography/mass spectrometry based metabolomics protocol by means of statistical experimental design

Metabolomics

Volumn 8, Issue 1, 2012, Pages 50-63

  Danielsson, Anders P H ^a,b   Moritz, Thomas ^c   Mulder, Hindrik ^a   Spégel, Peter ^a  

^a LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^b LUND INSTITUTE OF TECHNOLOGY   (Sweden)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Blood plasma; DOE; Gas chromatography; Mass spectrometry; Metabolomics; MTBSTFA

Indexed keywords

N TERT BUTYLDIMETHYLSILYL N METHYLTRIFLUOROACETAMIDE; TRIFLUOROACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ADULT; ARTICLE; BLOOD ANALYSIS; CHEMICAL MODIFICATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERIVATIZATION; DESILYLATION; EXPERIMENTAL DESIGN; FEMALE; FLOW RATE; HUMAN; HYDROLYSIS; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MASS FRAGMENTOGRAPHY; METABOLITE; METABOLOMICS; METHOXIMATION; PROCESS OPTIMIZATION; SIGNAL NOISE RATIO; SILYLATION; THERMOSTABILITY; VALIDATION STUDY;

EID: 84855879323     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-011-0283-6     Document Type: Article

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