Energy restriction negates NMDA receptor antagonist efficacy in ischemic stroke

NeuroMolecular Medicine

Volumn 13, Issue 3, 2011, Pages 175-178

  Yoon, Jeong Seon ^a   Mughal, Mohamed R ^a   Mattson, Mark P ^a,b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral ischemia; Diabetes; Dizocilpine; Excitotoxicity; MK 801; Obesity

Indexed keywords

DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; FOOD DRUG INTERACTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

ANIMALS; BRAIN ISCHEMIA; CALORIC RESTRICTION; ENERGY INTAKE; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; MALE; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION; RECEPTORS, N-METHYL-D-ASPARTATE; STROKE;

MUS; RODENTIA;

EID: 84855874814     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-011-8145-y     Document Type: Article

References (16)

1. Albers, G. W., Goldstein, L. B., Hall, D., Lesko, L. M., & Aptiganel Acute Stroke Investigators. (2001). Aptiganel hydrochloride in acute ischemic stroke: A randomized controlled trial. JAMA, 286, 2673-2682. (Pubitemid 33135073)
2. Arumugam, T. V., Phillips, T. M., Cheng, A., Morrell, C. H., Mattson, M. P., & Wan, R. (2010). Age and energy intake interact to modify cell stress pathways and stroke outcome. Annals of Neurology, 67, 41-52.
3. Boxer, P. A., Cordon, J. J., Mann, M. E., Rodolosi, L. C., Vartanian, M. G., Rock, D. M., et al. (1990). Comparison of phenytoin with noncompetitive N-methyl-D-aspartate antagonists in a model of focal brain ischemia in rat. Stroke, 21, S47-S51.
4. Cheng, B., & Mattson, M. P. (1994). NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain Research, 640, 56-67. (Pubitemid 24086531)
5. Hyun, D. H., Emerson, S. S., Jo, D. G., Mattson, M. P., & de Cabo, R. (2006). Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proceedings of the National Academy of Sciences USA, 103, 19908-199912.
6. Kochhar, A., Zivin, J. A., Lyden, P. D., & Mazzarella, V. (1988). Glutamate antagonist therapy reduces neurologic deficits produced by focal central nervous system ischemia. Archives of Neurology, 45, 148-153. (Pubitemid 18054529)
7. Ma, J., Endres, M., & Moskowitz, M. A. (1998). Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice. British Journal of Pharmacology, 124, 756-762. (Pubitemid 28276813)
8. Martin, B., Ji, S., Maudsley, S., & Mattson, M. P. (2010). "Control" laboratory rodents are metabolically morbid: Why it matters. Proceedings of the National Academy of Sciences USA, 107, 6127-6133.
9. Martin, B., Mattson, M. P., & Maudsley, S. (2006). Caloric restriction and intermittent fasting: Two potential diets for successful brain aging. Ageing Research Reviews, 5, 332-353. (Pubitemid 44374430)
10. Mattson, M. P., Lovell, M. A., Furukawa, K., & Markesbery, W. R. (1995). Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxi-dant enzyme activities in hippocampal neurons. Journal of Neurochemistry, 65, 1740-1751.
11. Minematsu, K., Fisher, M., Li, L., Davis, M. A., Knapp, A. G., Cotter, R. E., et al. (1993). Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology, 43, 397-403. (Pubitemid 23060278)
12. Robertson, C., Goodman, J. C., Grossman, R. G., Claypool, M., & White, A. (1992). Dietary nonprotein calories and cerebral infarction size in rats. Stroke, 23, 564-568.
13. Stranahan, A. M., Lee, K., Martin, B., Maudsley, S., Golden, E., Cutler, R. G., et al. (2009). Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus, 19, 951-961.
14. Tureyen, K., Bowen, K., Liang, J., Dempsey, R. J., & Vemuganti, R. (2011). Exacerbated brain damage, edema and inflammation in type-2 diabetic mice subjected to focal ischemia. Journal of Neurochemistry, 116, 499-507.
15. Uranga, R. M., Bruce-Keller, A. J., Morrison, C. D., Fernandez-Kim, S. O., Ebenezer, P. J., Zhang, L., et al. (2010). Intersection between metabolic dysfunction, high fat diet consumption, and brain aging. Journal of Neurochemistry, 114, 344-361.
16. Yoon, J. S., Lee, J. H., Son, T. G., Mughal, M. R., Greig, N. H., & Mattson, M. P. (2011). Pregabalin suppresses calcium-mediated proteolysis and improves stroke outcome. Neurobiology of Disease, 41, 624-629.