The plant limonoid 7-oxo-deacetoxygedunin inhibits RANKL-induced osteoclastogenesis by suppressing activation of the NF-κB and MAPK pathways

Biochemical and Biophysical Research Communications

Volumn 415, Issue 2, 2011, Pages 361-366

  Wisutsitthiwong, Chonnaree ^a   Buranaruk, Chayanit ^a   Pudhom, Khanitha ^a   Palaga, Tanapat ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

MAPK pathway; NF B pathway; Osteoclast; Plant limonoid; RANKL

Indexed keywords

7 OXO DEACETOXYGEDUNIN; CATHEPSIN K; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; LIMONOID; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PLANT EXTRACT; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; GENE EXPRESSION; GIANT CELL; IC 50; MACROPHAGE; MANGROVE; MONOCYTE; NONHUMAN; OSTEOCLASTOGENESIS; PLANT SEED; PRIORITY JOURNAL; STEM CELL; XYLOCARPUS MOLUCCENSIS;

ANIMALS; BONE REMODELING; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; OSTEOCLASTS; RANK LIGAND;

XYLOCARPUS MOLUCCENSIS;

EID: 84855872407     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.073     Document Type: Article

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