Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: Acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Munakata, Kaori ^a   Takashima, Kiyoe ^a   Nishiyama, Mitsue ^b   Asano, Naoko ^b   Mase, Akihito ^b   Hioki, Kyoji ^c   Ohnishi, Yasuyuki ^c   Yamamoto, Masahiro ^a,b   Watanabe, Kenji ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TSUMURA AND CO   (Japan)

^c CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON REGULATORY FACTOR 7; INTERFERON STIMULATED GENE FACTOR 3; JUZENTAIHOTO; PLANT EXTRACT; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEEDBACK SYSTEM; GENE; GENE EXPRESSION; GENE SEQUENCE; INTESTINE FLORA; IRF7 GENE; ISGF3G GENE; LARGE INTESTINE; MALE; MICROARRAY ANALYSIS; MOUSE; MOUSE STRAIN; NONHUMAN; PROMOTER REGION; SIGNAL TRANSDUCTION; SMALL INTESTINE; STAT1 GENE; STEADY STATE; STRAIN DIFFERENCE; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CLUSTER ANALYSIS; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TRADITIONAL MEDICINE;

ANIMALIA; MUS;

ANIMALS; CLUSTER ANALYSIS; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; INTERFERON-STIMULATED GENE FACTOR 3; MALE; MEDICINE, TRADITIONAL; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 84855869716     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-30     Document Type: Article

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