Antimicrobial peptides in Caenorhabditis elegans

Invertebrate Survival Journal

Volumn 7, Issue 1, 2010, Pages 45-52

  Bogaerts, Annelies ^a   Beets, I ^a   Schoofs, L ^a   Verleyen, P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

ABFs; Caenacins; Caenopores; Host pathogen interaction; Immunity; Insulin signalling

Indexed keywords

EID: 84855852625     PISSN: None     EISSN: 1824307X     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Abada EA, Sung H, Dwivedi M, Park BJ, Lee SK, Ahnn J. C. elegans behavior of preference choice on bacterial food. Mol. Cells 28: 209-213, 2009.
2. Alegado RA, Tan MW. Resistance to antimicrobial peptides contributes to persistence of Salmonella typhimurium in the C. elegans intestine. Cell. Microbiol. 10: 1259-1273, 2008.
3. Alper S, McBride SJ, Lackford B, Freedman JH, Schwartz DA. Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol. Cell. Biol. 27: 5544-5553, 2007.
4. Banyai L, Patthy L. Amoebapore homologs of Caenorhabditis elegans. Biochim. Biophys. Acta 1429: 259-264, 1998.
5. Brandazza A, Angeli S, Tegoni M, Cambillau C, Pelosi P. Plant stress proteins of the thaumatin-like family discovered in animals. FEBS Lett. 572: 3-7, 2004.
6. Brogden K. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3: 238-250, 2005.
7. Bruhn H. A short guided tour through functional and structural features of saposin-like proteins. Biochem. J. 389: 249-257, 2005.
8. Bulet P, Hetru C, Dimarcq JL, Hoffmann D. Antimicrobial peptides in insects; structure and function. Dev. Comp. Immunol. 23: 329-344, 1999.
9. Bulet P, Stöcklin R, Menin L. Anti-microbial peptides: from invertebrates to vertebrates. Immunol. Rev. 198: 169-184, 2004.
10. Chen X, Niyonsaba F, Ushio H, Okuda D, Nagaoka I, Ikeda S, et al. Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli. J Dermatol Sci. 40: 123-132, 2005.
11. Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, et al. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat. Immunol. 5: 488-494, 2004.
12. Evans EA, Kawli T, Tan MW. Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans. PLoS Pathog. 4: 1000175, 2008.
13. Fjell CD, Hancock RE, Cherkasov A. AMPer: a database and an automated discovery tool for antimicrobial peptides. Bioinformatics 23: 1148-1155, 2007.
14. Froy O. Convergent evolution of invertebrate defensins and nematode antibacterial factors. Trends Microbiol. 13: 314-319, 2005.
15. Grenier J, Potvin C, Trudel J, Asselin A. Some thaumatinlike proteins hydrolyse polymeric beta-1, 3-glucans. Plant J. 19: 473-480, 1999.
16. Jenssen H, Hamill P, Hancock RE. Peptide antimicrobial agents. Clin. Microbiol. Rev. 19: 491-511, 2006.
17. Kato Y. Nematode antimicrobial peptides. Curr. Top. Pept. Protein Res. 8: 1-10, 2007.
18. Kato Y, Aizawa T, Hoshino H, Kawano K, Nitta K, Zhang H. abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans. Biochem. J. 361: 221-230, 2002.
19. Kato Y, Komatsu S. ASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suum. Purification, primary structure and molecular cloning of cDNA. J. Biol. Chem. 271: 30493-30498, 1996.
20. Kurz CL, Tan MW. Regulation of aging and innate immunity in C. elegans. Aging Cell 3:185-193, 2004.
21. Leippe M. Antimicrobial and cytolytic polypeptides of amoeboid protozoa-effector molecules of primitive phagocytes. Dev. Comp. Immunol. 23: 267-279, 1999.
22. Mallo GV, Kurz CL, Couillault C, Pujol N, Granjeaud S, Kohara Y, et al. Inducible antibacterial defense system in C. elegans. Curr. Biol. 12: 1209-1214, 2002.
23. Means TK, Mylonakis E, Tampakakis E, Colvin RA, Seung E, Puckett L, et al. Evolutionarily conserved recognition and innate immunity to fungal pathogens by scavenger receptors SCARF1 and CD36. J. Exp. Med. 206: 637-653, 2009.
24. Minabi M, Ueno S, Pillai A, Kato Y. Evolution of ASABF-type antimicrobial peptides in nematodes: putative rearrangement of disulfide bonding patterns. Dev. Comp. Immunol. 33: 1147-1150, 2009.
25. Muir RE, Tan MW. Virulence of Leucobacter chromiireducens subsp. solipictus to Caenorhabditis elegans: characterization of a novel host-pathogen interaction. Appl. Environ. Microbiol. 74: 4185-4195, 2008.
26. Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283, 2003.
27. Mysliwy J, Dingley AJ, Stanisak M, Jung S, Lorenzen I, Roeder T et al. Caenopore-5: The three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans, Dev. Comp. Immunol. [in press].
28. Nathoo AN, Moeller RA, Westlund BA, Hart AC. Identification of neuropeptide-like protein gene families in Caenorhabditis elegans and other species. Proc. Natl. Acad. Sci. USA 98: 14000-14005, 2001.
29. Patthy L. Consensus approaches in detection of distant homologies. Method Enzymol. 266: 184-198, 1996.
30. Pillai A, Ueno S, Zhang H, Kato Y. Induction of ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptides by bacterial injection: novel members of ASABF in the nematode Ascaris suum. Biochem. J. 371: 663-668, 2003.
31. Pradel E, Zhang Y, Pujol N, Matsuyama T, Bargmann CI, Ewbank JJ. Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 104: 2295-2300, 2007.
32. Pujol N, Link EM, Liu LX, Kurz CL, Alloing G, Tan MW et al. A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans. Curr. Biol. 11: 809-821, 2001.
33. Pujol N, Cypowyj S, Ziegler K, Millet A, Astrain A, Goncharov A, et al. Distinct innate immune responses to infection and wounding in the C. elegans epidermis. Curr. Biol. 18: 481-489, 2008a.
34. Pujol N, Zugasti O, Wong D, Couillault C, Kurz CL, Schulenburg H, et al. Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides. Plos Pathogens 4, 2008b.
35. Ren M, Feng H, Fu Y, Land M, Rubin CS. Protein kinase D is an essential regulator of C. elegans innate immunity. Immunity 30: 521-532, 2009.
36. Rodrígeuz de le Vega RC, Possani LD. On the evolution of invertebrate defensins. Trends Genet. 19: 684-687, 2005.
37. Roeder T, Stanisak M, Gelhaus C, Bruchhaus I, Grotzinger J, Leippe M. Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity. Dev. Comp. Immunol. 34: 203-209, 2010.
38. Schulenburg H, Ewbank JJ. The genetics of pathogen avoidance in Caenorhabditis elegans. Mol. Microbiol. 66: 563-570, 2007.
39. Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, Tan MW. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc. Natl. Acad. Sci. USA 103: 14086-14091, 2006.
40. Shatters RG Jr, Boykin LM, Lapointe SL, Hunter WB, Weathersbee AA. Phylogenetic and structural relationships of the PR5 gene family reveal an ancient multigene family conserved in plants and select animal taxa. J. Mol. Evol. 63: 12-29, 2006.
41. Shtonda BB, Avery L. Dietary choice behaviour in Caenorhabditis elegans. J. Exp. Biol. 209: 89-102, 2006.
42. Styer KL, Singh V, Macosko E, Steele SE, Bargmann CI, Aballay A. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Science 322: 460-464, 2008.
43. Svensson B, Fukuda K, Nielsen PK, Bonsager BC. Proteinaceous alpha-amylase inhibitors. Biochim. Biophys. Acta 1696: 145-156, 2004.
44. Tenor JL, Aballay A. A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity. EMBO Rep. 9: 103-109, 2008.
45. Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet. 2: 183, 2006.
46. Vigers AJ, Roberts WK, Selitrennikoff CP. A new family of plant antifungal proteins. Mol. Plant-Microbe Interact. 4: 315-323, 1991.
47. Wong D, Bazopoulou D, Pujol N, Tavernarakis N, Ewbank JJ. Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection. Genome Biol. 8: R194, 2007.
48. Wu M, McClellan SA, Barrett RP, Zhang Y, Hazlett LD. Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis. J Immunol. 183: 8054-60, 2009.
49. Zhang H, Kato Y. Common structural properties specifically found in the CSalphabeta-type antimicrobial peptides in nematodes and mollusks: evidence for the same evolutionary origin? Dev. Comp Immunol. 27: 499-503, 2003.
50. Zhang H, Yoshida S, Aizawa T, Murakami R, Suzuki M, Koganezawa N, et al. In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum. Antimicrob. Agents Chemother. 44: 2701-2705, 2000.
51. Zhang Y, Lu H, Bargmann CI. Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature 438: 179-184, 2005.
52. Ziegler K, Kurz CL, Cypowyj S, Couillault C, Pophillat M, Pujol N, et al. Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade. Cell Host Microbe 5: 341-352, 2009.
53. Zugasti O, Ewbank JJ. Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-beta signaling pathway in Caenorhabditis elegans epidermis. Nat. Immunol. 10: 249-256, 2009.