Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension

Biochimie

Volumn 94, Issue 2, 2012, Pages 461-470

  Mourier, Gilles ^a   Hajj, Mariana ^b   Cordier, Florence ^c   Zorba, Adelajda ^c   Gao, Xinghuang ^a   Coskun, Tolga ^b   Herbet, Amaury ^b   Marcon, Elodie ^a   Beau, Fabrice ^a   Delepierre, Muriel ^c   Ducancel, Frédéric ^b   Servent, Denis ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b DIF   (France)

^c CNRS   (France)

Author keywords

Endothelin receptors; Endothelins; NMR; Pharmacological profile; Sarafotoxins

Indexed keywords

AMINO ACID; CALCIUM; CYSTEINE; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; SARAFOTOXIN; SARAFOTOXIN I3; SARAFOTOXIN M; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHO CELL; GENE OVEREXPRESSION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; STRUCTURE ANALYSIS; SYNTHESIS; TOXICITY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CALCIUM; CHO CELLS; CRICETINAE; ENDOTHELIN-1; INJECTIONS, INTRAVENOUS; ION TRANSPORT; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP; SURVIVAL RATE; TRANSFECTION; VASOCONSTRICTOR AGENTS; VIPER VENOMS;

ATRACTASPIS; ATRACTASPIS MICROLEPIDOTA; MUS;

EID: 84855843784     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.08.014     Document Type: Article

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