Mechanical versus alcohol-assisted epithelial debridement during photorefractive keratectomy: A confocal microscopic clinical trial

Journal of Refractive Surgery

Volumn 27, Issue 12, 2011, Pages 887-893

  Einollahi, Bahram ^a   Baradaran Rafii, Alireza ^a   Rezaei Kanavi, Mozhgan ^a   Eslani, Medi ^a   Parchegani, Mohammad Reza ^a   Zare, Mohammad ^a   Feizi, Sepehr ^a   Karimian, Farid ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL ASSISTED EPITHELIAL DEBRIDEMENT; ARTICLE; CELL DENSITY; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORNEA CELL; DEBRIDEMENT; FEMALE; HEALING; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTERNATIONAL STANDARD UNIT; MALE; MECHANICAL ASSISTED EPITHELIAL DEBRIDEMENT; OUTCOME ASSESSMENT; PHOTOREFRACTIVE KERATECTOMY; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; CELL COUNT; CORNEAL KERATOCYTES; CORNEAL STROMA; DEBRIDEMENT; EPITHELIUM, CORNEAL; ETHANOL; FEMALE; HUMANS; MALE; MECHANICAL PHENOMENA; MICROSCOPY, CONFOCAL; MYOPIA; PHOTOREFRACTIVE KERATECTOMY; PROSPECTIVE STUDIES; WOUND HEALING; YOUNG ADULT;

EID: 84855838763     PISSN: 1081597X     EISSN: 19382391     Source Type: Journal    
DOI: 10.3928/1081597X-20110823-02     Document Type: Article

References (30)

1. Taneri S, Weisberg M, Azar DT. Surface ablation techniques. J Cataract Refract Surg. 2011;37(2):392-408.
2. Netto MV, Barreto J Jr, Santo R, Bechara S, Kara-Jose N, Wilson SE. Synergistic effect of ethanol and mitomycin C on corneal stroma. J Refract Surg. 2008;24(6):626-632. (Pubitemid 351842089)
3. Carones F, Fiore T, Brancato R. Mechanical vs. alcohol epithelial removal during photorefractive keratectomy. J Refract Surg. 1999;15(5):556-562. (Pubitemid 29451137)
4. Kanitkar KD, Camp J, Humble H, Shen DJ, Wang MX. Pain after epithelial removal by ethanol-assisted mechanical versus transepithelial excimer laser debridement. J Refract Surg. 2000;16(5):519-522.
5. Lee HK, Lee KS, Kim JK, Kim HC, Seo KR, Kim EK. Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser. Am J Ophthalmol. 2005;139(1):56-63. (Pubitemid 40094840)
6. al-Abdulla NA, Jabbur NS, O'Brien TP. Astigmatism outcomes following spherical photorefractive keratectomy for myopia. J Refract Surg. 1998;14(6):610-614. (Pubitemid 28566637)
7. Wilson SE, He YG, Weng J, et al. Epithelial injury induces keratocyte apoptosis: hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing. Exp Eye Res. 1996;62(4):325-327.
8. Hanna KD, Pouliquen YM, Waring GO III, Savoldelli M, Fantes F, Thompson KP. Corneal wound healing in monkeys after repeated excimer laser photorefractive keratectomy. Arch Ophthalmol. 1992;110(9):1286-1291.
9. Fantes FE, Hanna KD, Waring GO III, Pouliquen Y, Thompson KP, Savoldelli M. Wound healing after excimer laser keratomileusis (photorefractive keratectomy) in monkeys. Arch Ophthalmol. 1990;108(5):665-675. (Pubitemid 20168823)
10. Dawson DG, Edelhauser HF, Grossniklaus HE. Long-term histopathologic findings in human corneal wounds after refractive surgical procedures. Am J Ophthalmol. 2005;139(1):168-178. (Pubitemid 40094856)
11. Ghirlando A, Gambato C, Midena E. LASEK and photorefractive keratectomy for myopia: clinical and confocal microscopy comparison. J Refract Surg. 2007;23(7):694-702. (Pubitemid 47424675)
12. Perez-Gomez I, Efron N. Change to corneal morphology after refractive surgery (myopic laser in situ keratomileusis) as viewed with a confocal microscope. Optom Vis Sci. 2003;80(10):690-697. (Pubitemid 37280471)
13. Erie JC, Patel SV, McLaren JW, Hodge DO, Bourne WM. Keratocyte density in the human cornea after photorefractive keratectomy. Arch Ophthalmol. 2003;121(6):770-776. (Pubitemid 36676212)
14. Erie JC, Patel SV, McLaren JW, Hodge DO, Bourne WM. Corneal keratocyte deficits after photorefractive keratectomy and laser in situ keratomileusis. Am J Ophthalmol. 2006;141(5):799-809.
15. Moilanen JA, Vesaluoma MH, Muller LJ, Tervo TM. Long-term corneal morphology after PRK by in vivo confocal microscopy. Invest Ophthalmol Vis Sci. 2003;44(3):1064-1069. (Pubitemid 36297822)
16. Wilson SE, Mohan RR, Ambrósio R Jr, Hung J, Lee J. The corneal wound healing response: cytokine-mediated interaction of the epithelium, stroma, and inflammatory cells. Prog Retin Eye Res. 2001;20(5):625-637. (Pubitemid 32695343)
17. Midena E, Gambato C, Miotto S, Cortese M, Salvi R, Ghirlando A. Long-term effects on corneal keratocytes of mitomycin C during photorefractive keratectomy: a randomized contralateral eye confocal microscopy study. J Refract Surg. 2007;23(9 Suppl):S1011-S1014. (Pubitemid 350175100)
18. Erie JC, McLaren JW, Hodge DO, Bourne WM. Long-term corneal keratoctye deficits after photorefractive keratectomy and laser in situ keratomileusis. Trans Am Ophthalmol Soc. 2005;103:56-66.
19. Erie JC, Nau CB, McLaren JW, Hodge DO, Bourne WM. Longterm keratocyte deficits in the corneal stroma after LASIK. Ophthalmology. 2004;111(7):1356- 1361. (Pubitemid 38844835)
20. Frueh BE, Cadez R, Böhnke M. In vivo confocal microscopy after photorefractive keratectomy in humans. A prospective, long-term study. Arch Ophthalmol. 1998;116(11):1425-1431. (Pubitemid 28520658)
21. Jester JV, Petroll WM, Cavanagh HD. Corneal stromal wound healing in refractive surgery: the role of myofibroblasts. Prog Retin Eye Res. 1999;18(3):311-356. (Pubitemid 29092610)
22. Balestrazzi E, De Molfetta V, Spadea L, et al. Histological, immunohistochemical, and ultrastructural findings in human corneas after photorefractive keratectomy. J Refract Surg. 1995;11(3):181-187.
23. Corbett MC, Prydal JI, Verma S, Oliver KM, Pande M, Marshall J. An in vivo investigation of the structures responsible for corneal haze after photorefractive keratectomy and their effect on visual function. Ophthalmology. 1996;103(9):1366-1380. (Pubitemid 26353041)
24. Moller-Pedersen T, Vogel M, Li HF, Petroll WM, Cavanagh HD, Jester JV. Quantification of stromal thinning, epithelial thickness, and corneal haze after photorefractive keratectomy using in vivo confocal microscopy. Ophthalmology. 1997;104(3):360-368. (Pubitemid 27120285)
25. Abad JC, An B, Power WJ, Foster CS, Azar DT, Talamo JH. A prospective evaluation of alcohol-assisted versus mechanical epithelial removal before photorefractive keratectomy. Ophthalmology. 1997;104(10):1566-1574.
26. de Medeiros FW, Mohan RR, Suto C, et al. Haze development after photorefractive keratectomy: mechanical vs ethanol epithelial removal in rabbits. J Refract Surg. 2008;24(9):923-927.
27. Helena MC, Baerveldt F, Kim WJ, Wilson SE. Keratocyte apoptosis after corneal surgery. Invest Ophthalmol Vis Sci. 1998;39(2):276-283. (Pubitemid 28093862)
28. Wilson SE, Mohan RR, Hong JW, Lee JS, Choi R. The wound healing response after laser in situ keratomileusis and photorefractive keratectomy: elusive control of biological variability and effect on custom laser vision correction. Arch Ophthalmol. 2001;119(6):889-896. (Pubitemid 32530319)
29. Watsky MA. Keratocyte gap junctional communication in normal and wounded rabbit corneas and human corneas. Invest Ophthalmol Vis Sci. 1995;36(13):2568-2576.
30. Chen CC, Chang JH, Lee JB, Javier J, Azar DT. Human corneal epithelial cell viability and morphology after dilute alcohol exposure. Invest Ophthalmol Vis Sci. 2002;43(8):2593-2602. (Pubitemid 34809447)