Nociception affects motor output: A review on sensory-motor interaction with focus on clinical implications

Clinical Journal of Pain

Volumn 28, Issue 2, 2012, Pages 175-181

  Nijs, Jo ^a,b,c   Daenen, Liesbeth ^a,b,d   Cras, Patrick ^d,e   Struyf, Filip ^a,b   Roussel, Nathalie ^a,d   Oostendorp, Rob A B ^f  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b Hogeschool Antwerpen   (Belgium)

^c UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

central sensitization; motor control; movement; musculoskeletal disorders; nociception; pain

Indexed keywords

ADRENERGIC SYSTEM; ARTICLE; BODY IMAGE; CHRONIC PAIN; EFFERENT NERVE; HUMAN; HYPERALGESIA; MUSCLE FORCE; MUSCLE FUNCTION; MUSCLE TRAINING; NEUROMUSCULAR BLOCKING; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PAIN; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PROPRIOCEPTION; SENSORIMOTOR FUNCTION; SKELETAL MUSCLE; SOMATOSENSORY CORTEX; SOMATOSENSORY STIMULATION; TRANSCRANIAL MAGNETIC STIMULATION; VASOCONSTRICTION;

ANIMALS; BRAIN; HUMANS; MODELS, NEUROLOGICAL; MOVEMENT; MUSCLE CONTRACTION; MUSCLE, SKELETAL; NOCICEPTION; PAIN; SPINAL CORD;

EID: 84855835501     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0b013e318225daf3     Document Type: Article

References (84)

1. Silverthorn DU. Human Physiology: An Integrated Approach. 4th edition. San Fransisco, CA, USA: Pearson Education Inc.; 2007:444-447.
2. Latash ML. Neurophysiological Basis of Movement. Leeds, United Kingdom: Human Kinetics; 1998:74.
3. Hodges PW, Moseley GL. Pain and motor control of the lumbopelvic region: effect and possible mechanisms. J Electromyogr Kinesiol. 2003;13:361-370. (Pubitemid 36794254)
4. Nijs J, Van Oosterwijck J, De Hertogh W. Rehabilitation of chronic whiplash: treatment of cervical dysfunctions or chronic pain syndrome? Clin Rheumatol. 2009;28:243-251.
5. Sterling M, Jull G, Vicenzino B, et al. Development of motor dysfunction following whiplash injury. Pain. 2003;103:65-73. (Pubitemid 36579086)
6. Schwenkreis P, Maier C, Tegenthoff M. Functional imaging of central nervous system involvement in complex regional pain syndrome. Am J Neuroradiol. 2009;30:1279-1284.
7. Nijs J, Van de Putte K, Louckx F, et al. Exercise performance and chronic pain in chronic fatigue syndrome: the role of pain catastrophizing. Pain Med. 2009;9:1164-1172.
8. Nijs J, Van Houdenhove B. From acute musculoskeletal pain to chronic widespread pain and fibromyalgia: application of pain neurophysiology in manual therapy practice. Manual Ther. 2009;14:3-12.
9. Henriksen M, Alkjaer T, Simonsen EB, et al. Experimental muscle pain during a forward lunge-the effects on knee joint dynamics and electromyographic activity. Br J Sports Med. 2009;43:503-507.
10. Hodges PW. The role of the motor system in spinal pain: implications for rehabilitation of the athlete following lower back pain. J Sci Med Sport. 2000;3:243-253. (Pubitemid 32186663)
11. Hodges PW, Richardson CA. Inefficient muscular stabilization of the lumbar spine associated with low back pain. A motor control evaluation of transversus abdominis. Spine. 1996;21: 2640-2650. (Pubitemid 26419101)
12. Tsao H, Galea MP, Hodges PW. Reorganization of the motor cortex is associated with postural control deficits in recurrent low back pain. Brain. 2008;131:2161-2171.
13. Hodges PW, Moseley GL, Gabrielsson A, et al. Experimental muscle pain changes feedforward postural responses of the trunk muscles. Exp Brain Res. 2003;151:262-271. (Pubitemid 36836532)
14. Graven-Nielsen T, Svensson P, Arendt-Nielsen L. Effects of experimental muscle pain on muscle activity and co-ordination during static and dynamic motor function. Electroencephal Clin Neurophysiol. 1997;105:156-164. (Pubitemid 27230281)
15. Farina D, Arendt-Nielsen L, Graven-Nielsen T. Experimental muscle pain decreases voluntary EMG activity but does not affect the muscle potential evoked by transcutaneous electrical stimulation. Clin Neurophysiol. 2005;116:1558-1565. (Pubitemid 40805436)
16. Farina D, Arendt-Nielsen L, Roatta S, et al. The pain-induced decrease in low-threshold motor unit discharge rate is not associated with the amount of increase in spike-triggered average torque. Clin Neurophysiol. 2008;119:43-51.
17. Falla D, Andersen H, Danneskiold-Samsøe B, et al. Adaptations of upper trapezius muscle activity during sustained contractions in women with fibromyalgia. J Electromyogr Kinesiol. 2010;20:457-464.
18. Farina S, Valeriani M, Rosso T, et al. Transient inhibition of the human cortex by capsaicin-induced pain. A study with transcranial magnetic stimulation. Neurosci Lett. 2001;314:97-101. (Pubitemid 33043813)
19. Valeriani M, Restuccia D, Di Lazzaro V, et al. Inhibition of the human primary motor area by painful heat stimulation of the skin. Clin Neurophysiol. 1999;110:1475-1480. (Pubitemid 29333887)
20. Le Pera D, Graven-Nielsen T, Valeriani M, et al. Inhibition of motor system excitability at cortical and spinal level by tonic muscle pain. Clin Neurophysiol. 2001;112:1633-1641. (Pubitemid 32763246)
21. Gill JR, Brown CA. A structured review of the evidence for pacing as a chronic pain intervention. Eur J Pain. 2009;13: 214-216.
22. Schaible HG, Grubb BD. Afferent and spinal mechanisms of joint pain. Pain. 1993;55:5-54. (Pubitemid 23300815)
23. Bandholm T, Rasmussen L, Aagaard P, et al. Effects of experimental muscle pain on shoulder-abduction force steadiness and muscle activity in healthy subjects. Eur J Appl Physiol. 2008;102:643-650.
24. Hodges PW, Ervilha UF, Graven-Nielsen T. Changes in motor unit firing rate in synergist muscles cannot explain the maintenance of force during constant force painful contractions. J Pain. 2008;9:1169-1174.
25. Tucker K, Butler J, Graven-Nielsen T, et al. Motor unit recruitment strategies are altered during deep-tissue pain. J Neurosci. 2009;29:10820-10826.
26. Tucker KJ, Hodges PW. Motoneurone recruitment is altered with pain induced in non-muscular tissue. Pain. 2009;141: 151-155.
27. Arendt-Nielsen L, Falla D. Motor control adjustments in musculoskeletal pain and the implications for pain recurrence. Pain. 2009;142:171-172.
28. Leo RJ, Latif T. Repetitive Transcranial Magnetic Stimulation (rTMS) in experimentally induced and chronic neuropathic pain: a review. J Pain. 2007;8:453-459. (Pubitemid 46843687)
29. Lefaucheur JP. The use of repetitive transcranial magnetic stimulation (rTMS) in chronic neuropathic pain. Clin Neurophysiol. 2006;36:117-124. (Pubitemid 44566463)
30. Leung A, Donohue M, Xu R, et al. rTMS for suppressing neuropathic pain: a meta-analysis. J Pain. 2009;10:1205-1216.
31. Passard A, Attal N, Benadhira R, et al. Effects of unilateral repetitive transcranial magnetic stimulation of the motor cortex on chronic widespread pain in fibromyalgia. Brain. 2007;130:2661-2670. (Pubitemid 47511708)
32. Mylius V. Pain relieving effects of repetitive transcranial magnetic stimulation of the motor cortex: what can we learn from experimentally-induced pain? Clin Neurophysiol. 2010; 121:807-808.
33. Capra NF, Ro JY. Experimental muscle pain produces central modulation of proprioceptive signals arising from jaw muscle spindles. Pain. 2000;86:151-162. (Pubitemid 30211714)
34. Rossi S, della Volpe R, Ginanneschi F, et al. Early somatosensory processing during tonic muscle pain in humans: relation to loss of proprioception and motor "defensive" strategies. Clin Neurophysiol. 2003;114:1351-1358. (Pubitemid 36776834)
35. Haigh RC, McCabe CS, Halligan P, et al. Joint stiffness in a phantom limb: evidence of central nervous system involvement in rheumatoid arthritis. Rheumatology. 2003;42:888-892. (Pubitemid 37220939)
36. Karl A, Birbaumer N, Lutzenberger W, et al. Reorganization of motor and somatosensory cortex in upper extremity amputees with phantom limb pain. J Neurosci. 2001;21: 3609-3618. (Pubitemid 32422825)
37. Flor H, Braun C, Elbert T, et al. Extensive reorganization of primary somatosensory cortex in chronic back pain patients. Neurosci Lett. 1997;224:5-8. (Pubitemid 27112856)
38. Knecht S, Henningsen H, Elbert T, et al. Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb. Neurosci Lett. 1995;201:262-264. (Pubitemid 26009991)
39. Maihöfner C, Handwerker HO, Neundörfer B, et al. Patterns of cortical reorganization in complex regional pain syndrome. Neurology. 2003;61:1707-1715. (Pubitemid 38020816)
40. Maihöfner C, Handwerker H, Neundörfer B, et al. Cortical reorganization during recovery from complex regional pain syndrome. Neuroogy. 2004;63:693-701. (Pubitemid 39100828)
41. Knecht S, Soros P, Gurtler S, et al. Phantom sensations following acute pain. Pain. 1998;77:209-213. (Pubitemid 28403552)
42. Birbaumer N, Lutzenberger W, Montoya P, et al. Effects of regional anesthesia on phantom limb pain are mirrored in changes in cortical reorganization. J Neurosci. 1997;17: 5503-5508. (Pubitemid 27300315)
43. Flor H, Birbaumer N. Phantom limb pain: cortical plasticity and novel therapeutic approaches. Curr Opin Anaesthesiol. 2000;13:561-564.
44. Byl NN, Nagarajan S, McKenzie AL. Effect od sensory discrimination training on structure and function in patients with focal hand dystonia: a case series. Arch Phys Rehabil. 2003;84:1505-1514. (Pubitemid 37237260)
45. Passatore M, Roatta S. Influence of sympathetic nervous system on sensorimotor function: whiplash associated disorders (WAD degree as a model). Eur J Appl Physiol. 2006;98: 423-449. (Pubitemid 44882605)
46. Sjögaard G, Sögaard K. Muscle injury in repetitive motion disorders. Clin Orthop Rel Res. 1998;351:21-31. (Pubitemid 28275384)
47. Akoev GN. Catecholamines, acetylcholine and excitability of mechanoreceptors. Prog Neurobiol. 1981;15:269-294. (Pubitemid 11179955)
48. Madeleine P, Mathiassen SE, Arendt-Nielsen L. Changes in the degree of motor variability associated with experimental and chronic neck-shoulder pain during a standardized repetitive arm movement. Exp Brain Res. 2008;185:689-698.
49. Falla D, Lindstrøm R, Rechter L, et al. Effect of pain on the modulation in discharge rate of sternocleidomastoid motor units with force direction. Clin Neurophysiol. 2010;121:744-753.
50. Falla D, Farina D, Kanstrup Dahl M, et al. Muscle pain induces task-dependent changes in cervical agonist/antagonist activity. J Appl Physiol. 2007;102:601-609. (Pubitemid 46220888)
51. Le Bars D. The whole body receptive field of dorsal horn multireceptive neurones. Brain Res Rev. 2002;40:29-44. (Pubitemid 36183156)
52. Fields HL. Role of central chages in secondary hyperalgesia: overview. In: Willis W, ed. Hyperalgesia and Allodynia. New York: Raven Press; 1992.
53. Meyer RA, Campbell JN, Raja SN. Peripheral neural mechanisms of nociception. In: Wall PD, Melzack R, eds. Textbook of Pain. 3rd ed. Churchill Livingstone: Edinburgh; 1995:13-44.
54. Staud R, Craggs JG, RobinsonME, et al. Brain activity related to temporal summation of C-fiber evoked pain. Pain. 2007;129: 130-142. (Pubitemid 46551377)
55. Meeus M, Nijs J, Van de Wauwer N, et al. Diffuse noxious inhibitory control is delayed in chronic fatigue syndrome: an experimental study. Pain. 2008;139:439-448.
56. Meeus M, Nijs J. Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome. Clin Rheumatol. 2007;26:465-473. (Pubitemid 46359284)
57. Zhuo M. A synaptic model for pain: long-term potentiation in the anterior cingulated cortex. Mol Cells. 2007;23:259-271. (Pubitemid 47181042)
58. Seifert F, Maihöfner C. Central mechanisms of experimental and chronic neuropathic pain: Findings from functional imaging studies. Cell Mol Life Sci. 2009;66:375-390.
59. Schwoebel J, Coslett HB, Bradt J, et al. Pain and the body schema: effects of pain severity on mental representations of movement. Neurology. 2002;59:775-777.
60. Fiorio M, Tinazzi M, Ionta S, et al. Mental rotation of body parts and non-corporeal objects in patients with idiopathic cervical dystonia. Neuropsychologia. 2007;45:2346-2354. (Pubitemid 46678093)
61. McCabe CS, Haigh RC, Shenker NG, et al. Phantoms in rheumatology. Novartis Found Symp. 2004;260:154-178. (Pubitemid 41322991)
62. Moseley GL, Sim DF, Henry ML, et al. Experimental hand pain delays recognition of the contralateral hand: evidence that acute and chronic pain have opposite effects on information processing? Cogn Brain Res. 2005;25:188-194. (Pubitemid 41278496)
63. Moseley GL. I can't find it! Distorted body image and tactile dysfunction in patients with chronic back pain. Pain. 2008;140:239-243.
64. Nijs J, Van Houdenhove B, Oostendorp RAB. Recognition of central sensitization in patients with musculoskeletal pain: application of pain neurophysiology in manual therapy practice. Manual Ther. 2010;15:135-141.
65. Falla D, Jull G, Edwards S, et al. Neuromuscular efficiency of the sternocleidomastoid and anterior scalene muscles in patients with neck pain. Disabil Rehabil. 2004;26:712-717. (Pubitemid 38878402)
66. MacDonald D, Moseley GL, Hodges PW. Why do some patients keep hurting their back? Evidence of ongoing back muscle dysfunction during remission from recurrent back pain. Pain. 2009;142:183-188.
67. Quintero GC, Erzurumlu RS, Vaccarino AL. Evaluation of morphine analgesia and motor coordination in mice following cortex-specific knockout of the N-methyl-D-aspartate NR1-subunit. Neurosci Lett. 2008;437:55-58.
68. Le Pera D, Brancucci A, DE Armas L, et al. Inhibitory effect of voluntary movement preparation on cutaneous heat pain and laser-evoked potentials. Eur J Neurosci. 2007;25:1900-1907. (Pubitemid 46549991)
69. Skyba DA, Radhakrishnan R, Rohlwing JJ, et al. Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord. Pain. 2003;106:159-168. (Pubitemid 37329626)
70. Mauger AR, Jones AM, Williams CA. Influence of acetaminophen on performance during time trial cycling. J Appl Physiol. 2010;108:98-104.
71. Pickering G, Estève V, Loriot MA, et al. Acetaminophen reinforces descending inhibitory pathways. Clin Pharmacol Ther. 2008;84:47-51. (Pubitemid 351861483)
72. Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci. 1984;7:309-338. (Pubitemid 14155301)
73. Goldstein DJ, Lu Y, Detke MJ, et al. Duloxetine versus placebo in patients with painful diabetic neuropathy. Pain. 2005;116:109-118. (Pubitemid 40828506)
74. Arnold LM, Lu Y, Crofford LJ, et al. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Athritis Rheum. 2004;50:2974-2984. (Pubitemid 39209537)
75. Chappell AS, Ossanna MJ, Liu-Seifert H, et al. Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebocontrolled trial. Pain. 2009;146:253-260.
76. Sharar SR, Miller W, Teeley A, et al. Applications of virtual reality for pain management in burn-injured patients. Expert Rev Neurother. 2008;8:1667-1674.
77. Wismeijer AAJ, Vingerhoets JJM. The use of virtual reality and audiovisual eyeglass systems as adjunct analgesic techniques: a review of the literature. Ann Behav Med. 2005; 30:268-278. (Pubitemid 41832020)
78. Gold JI, Belmont KA, Thomas DA. The neurobiology of virtual reality pain attenuation. Cyberpsychol Behav. 2007; 10:536-544. (Pubitemid 47328667)
79. DeSantana JM, Da Silva LF, De Resende MA, et al. Transcutaneous electrical nerve stimulation at both high and low frequencies activates ventrolateral periaqueductal grey to decrease mechanical hyperalgesia in arthritic rats. Neuroscience. 2009;163:1233-1241.
80. Kalra A, Urban MO, Sluka KA. Blockade of opioid receptors in rostral ventral medulla prevents antihyperalgesia produced by transcutaneous electrical nerve stimulation (TENS). J Pharmacol Exp Ther. 2001;298:257-263. (Pubitemid 32574535)
81. Moss P, Sluka K, Wright A. The initial effects of knee joint mobilization on osteoarthritic hyperalgesia. Manual Ther. 2007;12:109-118. (Pubitemid 46602065)
82. Sluka KA, Skyba DA, Radhakrishnan R, et al. Joint mobilization reduces hyperalgesia associated with chronic muscle and joint inflammation in rats. J Pain. 2006;7:602-607. (Pubitemid 44119292)
83. Sluka KA, Wright A. Knee joint mobilization reduces secondary mechanical hyperalgesia induced by capsaicin injection into the ankle joint. Eur J Pain. 2001;5:81-87. (Pubitemid 32661930)
84. Sluka KA, Bailey K, Bogush J, et al. Treatment with either high or low frequency TENS reduces secondary hyperalgesia observed after injection of kaolin and carrageenan into the knee joint. Pain. 1998;77:97-102. (Pubitemid 28398839)