rTMS for Suppressing Neuropathic Pain: A Meta-Analysis

Journal of Pain

Volumn 10, Issue 12, 2009, Pages 1205-1216

  Leung, Albert ^a   Donohue, Michael ^a   Xu, Ronghui ^b   Lee, Ryan ^b   Lefaucheur, Jean Pascal ^c   Khedr, Eman M ^d   Saitoh, Youichi ^e   André Obadia, Nathalie ^f   Rollnik, Jens ^g   Wallace, Mark ^a   Chen, Robert ^h  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HENRI MONDOR HOSPITAL   (France)

^d ASSIUT UNIVERSITY   (Egypt)

^e OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f CENTRE HOSPITALIER LYON SUD   (France)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

meta analysis; neuromodulation; neuropathic pain; rTMS; TMS; Transcranial magnetic stimulation

Indexed keywords

ANALGESIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DISEASE DURATION; HUMAN; META ANALYSIS; MOTOR CORTEX; NEUROANATOMY; NEUROMODULATION; NEUROPATHIC PAIN; PATHOPHYSIOLOGY; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REVIEW; SYSTEMATIC REVIEW; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

DATABASES, FACTUAL; FEMALE; HUMANS; MALE; NEURALGIA; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 68249105673     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2009.03.010     Document Type: Review

References (87)

1. Cooke S.F., and Bliss T.V. Plasticity in the human central nervous system. Brain 129 Pt 7 (2006) 1659-1673
2. Farajidavar A., Saeb S., and Behbehani K. Incorporating synaptic time-dependent plasticity and dynamic synapse into a computational model of wind-up. Neural Netw 21 (2008) 241-249
3. Lang S., Klein T., Magerl W., and Treede R.D. Modality-specific sensory changes in humans after the induction of long-term potentiation (LTP) in cutaneous nociceptive pathways. Pain 128 (2007) 254-263
4. Ren K., and Dubner R. Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: Role of BDNF-TrkB signaling and NMDA receptors. Mol Neurobiol 35 (2007) 224-235
5. Sandkuhler J. Understanding LTP in pain pathways. Mol Pain 3 (2007) 9
6. Zhuo M. Molecular mechanisms of pain in the anterior cingulate cortex. J Neurosci Res 84 (2006) 927-933
7. Lefaucheur J.P. New insights into the therapeutic potential of non-invasive transcranial cortical stimulation in chronic neuropathic pain. Pain 122 (2006) 11-13
8. Canavero S., and Bonicalzi V. Extradural cortical stimulation for central pain. Acta Neurochir Suppl 97 (2007) 27-36
9. Aleman A., Sommer I.E., and Kahn R.S. Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: A meta-analysis. J Clin Psychiatry 68 (2007) 416-421
10. Simons W., and Dierick M. Transcranial magnetic stimulation as a therapeutic tool in psychiatry. World J Biol Psychiatry 6 (2005) 6-25
11. Loo C.K., and Mitchell P.B. A review of the efficacy of transcranial magnetic stimulation (TMS) treatment for depression, and current and future strategies to optimize efficacy. J Affect Disord 88 (2005) 255-267
12. Krause P, Forderreuther S, Straube A: [Motor cortical representation in patients with complex regional pain syndrome A TMS study]. Schmerz 2005
13. Pridmore S., and Oberoi G. Transcranial magnetic stimulation applications and potential use in chronic pain: Studies in waiting. J Neurol Sci 182 (2000) 1-4
14. Leo R.J., and Latif T. Repetitive transcranial magnetic stimulation (rTMS) in experimentally induced and chronic neuropathic pain: A review. J Pain 8 (2007) 453-459
15. Moher D., and Pham B. Meta-analysis: An adolescent in need of evidence and a watchful eye. Ann Med 31 (1999) 153-155
16. Wassermann E.M., Grafman J., Berry C., Hollnagel C., Wild K., Clark K., and Hallett M. Use and safety of a new repetitive transcranial magnetic stimulator. Electroencephalogr Clin Neurophysiol 101 (1996) 412-417
17. Zeger S.L., and Liang K.Y. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42 (1986) 121-130
18. Lefaucheur J.P., Drouot X., Keravel Y., and Nguyen J.P. Pain relief induced by repetitive transcranial magnetic stimulation of precentral cortex. Neuroreport 12 (2001) 2963-2965
19. Lefaucheur J.P., Drouot X., Menard-Lefaucheur I., Zerah F., Bendib B., Cesaro P., Keravel Y., and Nguyen J.P. Neurogenic pain relief by repetitive transcranial magnetic cortical stimulation depends on the origin and the site of pain. J Neurol Neurosurg Psychiatry 75 (2004) 612-616
20. Lefaucheur J.P., Drouot X., and Nguyen J.P. Interventional neurophysiology for pain control: Duration of pain relief following repetitive transcranial magnetic stimulation of the motor cortex. Neurophysiol Clin 31 (2001) 247-252
21. Hirayama A., Saitoh Y., Kishima H., Shimokawa T., Oshino S., Hirata M., Kato A., and Yoshimine T. Reduction of intractable deafferentation pain by navigation-guided repetitive transcranial magnetic stimulation of the primary motor cortex. Pain 122 (2006) 22-27
22. Khedr E.M., Kotb H., Kamel N.F., Ahmed M.A., Sadek R., and Rothwell J.C. Longlasting antalgic effects of daily sessions of repetitive transcranial magnetic stimulation in central and peripheral neuropathic pain. J Neurol Neurosurg Psychiatry 76 (2005) 833-838
23. Pleger B., Janssen F., Schwenkreis P., Volker B., Maier C., and Tegenthoff M. Repetitive transcranial magnetic stimulation of the motor cortex attenuates pain perception in complex regional pain syndrome type I. Neurosci Lett 356 (2004) 87-90
24. Rollnik J.D., Wustefeld S., Dauper J., Karst M., Fink M., Kossev A., and Dengler R. Repetitive transcranial magnetic stimulation for the treatment of chronic pain: A pilot study. Eur Neurol 48 (2002) 6-10
25. Andre-Obadia N., Peyron R., Mertens P., Mauguiere F., Laurent B., and Garcia-Larrea L. Transcranial magnetic stimulation for pain control: Double-blind study of different frequencies against placebo, and correlation with motor cortex stimulation efficacy. Clin Neurophysiol 117 (2006) 1536-1544
26. Avery D.H., Holtzheimer III P.E., Fawaz W., Russo J., Neumaier J., Dunner D.L., Haynor D.R., Claypoole K.H., Wajdik C., and Roy-Byrne P. Transcranial magnetic stimulation reduces pain in patients with major depression: A sham-controlled study. J Nerv Ment Dis 195 (2007) 378-381
27. Borckardt J.J., Weinstein M., Reeves S.T., Kozel F.A., Nahas Z., Smith A.R., Byrne T.K., Morgan K., and George M.S. Postoperative left prefrontal repetitive transcranial magnetic stimulation reduces patient-controlled analgesia use. Anesthesiology 105 (2006) 557-562
28. Brighina F., Piazza A., Vitello G., Aloisio A., Palermo A., Daniele O., and Fierro B. rTMS of the prefrontal cortex in the treatment of chronic migraine: A pilot study. J Neurol Sci 227 (2004) 67-71
29. Clarke B.M., Upton A.R., Kamath M.V., Al-Harbi T., and Castellanos C.M. Transcranial magnetic stimulation for migraine: Clinical effects. J Headache Pain 7 (2006) 341-346
30. Fregni F., DaSilva D., Potvin K., Ramos-Estebanez C., Cohen D., Pascual-Leone A., and Freedman S.D. Treatment of chronic visceral pain with brain stimulation. Ann Neurol 58 (2005) 971-972
31. Fregni F., Boggio P.S., Lima M.C., Ferreira M.J., Wagner T., Rigonatti S.P., Castro A.W., Souza D.R., Riberto M., Freedman S.D., Nitsche M.A., and Pascual-Leone A. A sham-controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury. Pain 122 (2006) 197-209
32. Graff-Guerrero A., Gonzalez-Olvera J., Fresan A., Gomez-Martin D., Mendez-Nunez J.C., and Pellicer F. Repetitive transcranial magnetic stimulation of dorsolateral prefrontal cortex increases tolerance to human experimental pain. Brain Res Cogn Brain Res 25 (2005) 153-160
33. Inghilleri M., Conte A., Frasca V., Curra A., Gilio F., Manfredi M., and Berardelli A. Antiepileptic drugs and cortical excitability: A study with repetitive transcranial stimulation. Exp Brain Res 154 (2004) 488-493
34. Kofler M., Glocker F.X., Leis A.A., Seifert C., Wissel J., Kronenberg M.F., and Fuhr P. Modulation of upper extremity motoneurone excitability following noxious finger tip stimulation in man: A study with transcranial magnetic stimulation. Neurosci Lett 246 (1998) 97-100
35. Lee S.H., Kim W., Chung Y.C., Jung K.H., Bahk W.M., Jun T.Y., Kim K.S., George M.S., and Chae J.H. A double blind study showing that two weeks of daily repetitive TMS over the left or right temporoparietal cortex reduces symptoms in patients with schizophrenia who are having treatment-refractory auditory hallucinations. Neurosci Lett 376 (2005) 177-181
36. Mosimann U.P., Rihs T.A., Engeler J., Fisch H., and Schlaepfer T.E. Mood effects of repetitive transcranial magnetic stimulation of left prefrontal cortex in healthy volunteers. Psychiatry Res 94 (2000) 251-256
37. Padberg F., Zwanzger P., Keck M.E., Kathmann N., Mikhaiel P., Ella R., Rupprecht P., Thoma H., Hampel H., Toschi N., and Moller H.J. Repetitive transcranial magnetic stimulation (rTMS) in major depression: Relation between efficacy and stimulation intensity. Neuropsychopharmacology 27 (2002) 638-645
38. Pope M.H., Phillips R.B., Haugh L.D., Hsieh C.Y., MacDonald L., and Haldeman S. A prospective randomized three-week trial of spinal manipulation, transcutaneous muscle stimulation, massage and corset in the treatment of subacute low back pain. Spine 19 (1994) 2571-2577
39. Passard A., Attal N., Benadhira R., Brasseur L., Saba G., Sichere P., Perrot S., Januel D., and Bouhassira D. Effects of unilateral repetitive transcranial magnetic stimulation of the motor cortex on chronic widespread pain in fibromyalgia. Brain 130 (2007) 2661-2670
40. Rosenberg J.M., Levy R.C., Cicmanec J.F., Hedges J.R., and Burke B.M. Single-dose ceftriaxone treatment of urinary tract infections. Ann Emerg Med 14 (1985) 970-972
41. Schwenkreis P., Janssen F., Rommel O., Pleger B., Volker B., Hosbach I., Dertwinkel R., Maier C., and Tegenthoff M. Bilateral motor cortex disinhibition in complex regional pain syndrome (CRPS) type I of the hand. Neurology 61 (2003) 515-519
42. Smania N., Corato E., Fiaschi A., Pietropoli P., Aglioti S.M., and Tinazzi M. Repetitive magnetic stimulation: A novel therapeutic approach for myofascial pain syndrome. J Neurol 252 (2005) 307-314
43. Svensson P., Miles T.S., McKay D., and Ridding M.C. Suppression of motor evoked potentials in a hand muscle following prolonged painful stimulation. Eur J Pain 7 (2003) 55-62
44. Cioni B., and Meglio M. Motor cortex stimulation for chronic non-malignant pain: Current state and future prospects. Acta Neurochir Suppl 97 (2007) 45-49
45. Fregni F., and Pascual-Leone A. Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS. Nat Clin Pract Neurol 3 (2007) 383-393
46. Lefaucheur J.P. Use of repetitive transcranial magnetic stimulation in pain relief. Expert Rev Neurother 8 (2008) 799-808
47. Stewart L.A., and Parmar M.K. Meta-analysis of the literature or of individual patient data: Is there a difference?. Lancet 341 (1993) 418-422
48. Clarke M.J., and Stewart L.A. Systematic reviews of randomized controlled trials: The need for complete data. J Eval Clin Pract 1 (1995) 119-126
49. Chen R., Classen J., Gerloff C., Celnik P., Wassermann E.M., Hallett M., and Cohen L.G. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 48 (1997) 1398-1403
50. Wassermann E.M. Risk and safety of repetitive transcranial magnetic stimulation: Report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. Electroencephalogr Clin Neurophysiol 108 (1998) 1-16
51. Cruccu G., Aziz T.Z., Garcia-Larrea L., Hansson P., Jensen T.S., Lefaucheur J.P., Simpson B.A., and Taylor R.S. EFNS guidelines on neurostimulation therapy for neuropathic pain. Eur J Neurol 14 (2007) 952-970
52. Nguyen J.P., Lefaucheur J.P., Decq P., Uchiyama T., Carpentier A., Fontaine D., Brugieres P., Pollin B., Feve A., Rostaing S., Cesaro P., and Keravel Y. Chronic motor cortex stimulation in the treatment of central and neuropathic pain: Correlations between clinical, electrophysiological and anatomical data. Pain 82 (1999) 245-251
53. Shortland P., Kinman E., and Molander C. Sprouting of A-fibre primary afferents into lamina II in two rat models of neuropathic pain. Eur J Pain 1 (1997) 215-227
54. Mannion R.J., Doubell T.P., Coggeshall R.E., and Woolf C.J. Collateral sprouting of uninjured primary afferent A-fibers into the superficial dorsal horn of the adult rat spinal cord after topical capsaicin treatment to the sciatic nerve. J Neurosci 16 (1996) 5189-5195
55. Lekan H.A., Carlton S.M., and Coggeshall R.E. Sprouting of A beta fibers into lamina II of the rat dorsal horn in peripheral neuropathy. Neurosci Lett 208 (1996) 147-150
56. Chung K., Lee B.H., Yoon Y.W., and Chung J.M. Sympathetic sprouting in the dorsal root ganglia of the injured peripheral nerve in a rat neuropathic pain model. J Comp Neurol 376 (1996) 241-252
57. Chung K., Yoon Y.W., and Chung J.M. Sprouting sympathetic fibers form synaptic varicosities in the dorsal root ganglion of the rat with neuropathic injury. Brain Res 751 (1997) 275-280
58. Garcia-Poblete E., Fernandez-Garcia H., Moro-Rodriguez E., Catala-Rodriguez M., Rico-Morales M.L., Garcia-Gomez-de-las-Heras S., and Palomar-Gallego M.A. Sympathetic sprouting in dorsal root ganglia (DRG): A recent histological finding?. Histol Histopathol 18 (2003) 575-586
59. Kim H.J., Na H.S., Sung B., Nam H.J., Chung Y.J., and Hong S.K. Is sympathetic sprouting in the dorsal root ganglia responsible for the production of neuropathic pain in a rat model?. Neurosci Lett 269 (1999) 103-106
60. Kim H.J., Na H.S., Back S.K., and Hong S.K. Sympathetic sprouting in sensory ganglia depends on the number of injured neurons. Neuroreport 12 (2001) 3529-3532
61. Lee B.H., Yoon Y.W., Chung K., and Chung J.M. Comparison of sympathetic sprouting in sensory ganglia in three animal models of neuropathic pain. Exp Brain Res 120 (1998) 432-438
62. Ramer M.S., and Bisby M.A. Normal and injury-induced sympathetic innervation of rat dorsal root ganglia increases with age. J Comp Neurol 394 (1998) 38-47
63. Shinder V., Govrin-Lippmann R., Cohen S., Belenky M., Ilin P., Fried K., Wilkinson H.A., and Devor M. Structural basis of sympathetic-sensory coupling in rat and human dorsal root ganglia following peripheral nerve injury. J Neurocytol 28 (1999) 743-761
64. Ramer M.S., French G.D., and Bisby M.A. Wallerian degeneration is required for both neuropathic pain and sympathetic sprouting into the DRG. Pain 72 (1997) 71-78
65. Ramer M.S., and Bisby M.A. Rapid sprouting of sympathetic axons in dorsal root ganglia of rats with a chronic constriction injury. Pain 70 (1997) 237-244
66. Chang L., Berman S., Mayer E.A., Suyenobu B., Derbyshire S., Naliboff B., Vogt B., FitzGerald L., and Mandelkern M.A. Brain responses to visceral and somatic stimuli in patients with irritable bowel syndrome with and without fibromyalgia. Am J Gastroenterol 98 (2003) 1354-1361
67. Gracely R.H., Geisser M.E., Giesecke T., Grant M.A., Petzke F., Williams D.A., and Clauw D.J. Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain 127 (2004) 835-843
68. LaGraize S.C., and Fuchs P.N. GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior. Exp Neurol 204 (2007) 182-194
69. Lorenz J., and Casey K.L. Imaging of acute versus pathological pain in humans. Eur J Pain 9 (2005) 163-165
70. Gieteling E.W., van Rijn M.A., de Jong B.M., Hoogduin J.M., Renken R., van Hilten J.J., and Leenders K.L. Cerebral activation during motor imagery in complex regional pain syndrome type 1 with dystonia. Pain 134 (2008) 30230-30239
71. Maihofner C., Baron R., DeCol R., Binder A., Birklein F., Deuschl G., Handwerker H.O., and Schattschneider J. The motor system shows adaptive changes in complex regional pain syndrome. Brain 130 (2007) 2671-2687
72. Maihofner C., Forster C., Birklein F., Neundorfer B., and Handwerker H.O. Brain processing during mechanical hyperalgesia in complex regional pain syndrome: A functional MRI study. Pain 114 (2005) 93-103
73. Maihofner C., Handwerker H.O., and Birklein F. Functional imaging of allodynia in complex regional pain syndrome. Neurology 66 (2006) 711-717
74. Maihofner C., Handwerker H.O., Neundorfer B., and Birklein F. Patterns of cortical reorganization in complex regional pain syndrome. Neurology 61 (2003) 1707-1715
75. Pleger B., Ragert P., Schwenkreis P., Forster A.F., Wilimzig C., Dinse H., Nicolas V., Maier C., and Tegenthoff M. Patterns of cortical reorganization parallel impaired tactile discrimination and pain intensity in complex regional pain syndrome. Neuroimage 32 (2006) 503-510
76. Funamizu H., Ogiue-Ikeda M., Mukai H., Kawato S., and Ueno S. Acute repetitive transcranial magnetic stimulation reactivates dopaminergic system in lesion rats. Neurosci Lett 383 (2005) 77-81
77. Strafella A.P., Paus T., Barrett J., and Dagher A. Repetitive transcranial magnetic stimulation of the human prefrontal cortex induces dopamine release in the caudate nucleus. J Neurosci 21 (2001) RC157
78. Strafella A.P., Paus T., Fraraccio M., and Dagher A. Striatal dopamine release induced by repetitive transcranial magnetic stimulation of the human motor cortex. Brain 126 (2003) 2609-2615
79. Garcia-Larrea L., and Peyron R. Motor cortex stimulation for neuropathic pain: From phenomenology to mechanisms. Neuroimage 37 Suppl 1 (2007) S71-S79
80. Garcia-Larrea L., Peyron R., Mertens P., Gregoire M.C., Lavenne F., Le Bars D., Convers P., Mauguiere F., Sindou M., and Laurent B. Electrical stimulation of motor cortex for pain control: A combined PET-scan and electrophysiological study. Pain 83 (1999) 259-273
81. Peyron R., Faillenot I., Mertens P., Laurent B., and Garcia-Larrea L. Motor cortex stimulation in neuropathic pain: Correlations between analgesic effect and hemodynamic changes in the brain: A PET study. Neuroimage 34 (2007) 310-321
82. Peyron R., Garcia-Larrea L., Deiber M.P., Cinotti L., Convers P., Sindou M., Mauguiere F., and Laurent B. Electrical stimulation of precentral cortical area in the treatment of central pain: Electrophysiological and PET study. Pain 62 (1995) 275-286
83. Reis J., Swayne O.B., Vandermeeren Y., Camus M., Dimyan M.A., Harris-Love M., Perez M.A., Ragert P., Rothwell J.C., and Cohen L.G. Contribution of transcranial magnetic stimulation to the understanding of cortical mechanisms involved in motor control. J Physiol 586 (2008) 325-351
84. Senapati A.K., Huntington P.J., and Peng Y.B. Spinal dorsal horn neuron response to mechanical stimuli is decreased by electrical stimulation of the primary motor cortex. Brain Res 1036 (2005) 173-179
85. Turton A.J., McCabe C.S., Harris N., and Filipovic S.R. Sensorimotor integration in complex regional pain syndrome: A transcranial magnetic stimulation study. Pain 127 (2007) 270-275
86. Maarrawi J., Peyron R., Mertens P., Costes N., Magnin M., Sindou M., Laurent B., and Garcia-Larrea L. Motor cortex stimulation for pain control induces changes in the endogenous opioid system. Neurology 69 (2007) 827-834
87. Maarrawi J., Peyron R., Mertens P., Costes N., Magnin M., Sindou M., Laurent B., and Garcia-Larrea L. Differential brain opioid receptor availability in central and peripheral neuropathic pain. Pain 127 (2007) 183-194