Umbilical cord perivascular cells: A mesenchymal cell source for treatment of tendon injuries

Open Tissue Engineering and Regenerative Medicine Journal

Volumn 4, Issue SPEC. ISSUE 1, 2011, Pages 112-119

  Emrani, Hamideh ^a   Davies, John E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Achilles tendon; Collagenase injury model; HUCPVC; Rat; Regeneration; Tendon repair; Tensile strength; Umbilical cord

Indexed keywords

BETA ACTIN; COLLAGEN TYPE 1; CD68 ANTIGEN; COLLAGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ELONGATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; FRACTURE HEALING; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; NUDE RAT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; TENDON INJURY; TENSILE STRENGTH; ACHILLES TENDON; ANIMAL CELL; ANTIBODY LABELING; CELL ISOLATION; CELL POPULATION; CELL SURVIVAL; CELL THERAPY; HORSE; MESENCHYMAL STEM CELL; MUSCLE REGENERATION; MUSCLE STIFFNESS; PERICYTE; PERIVASCULAR CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL CORD; YOUNG MODULUS;

ANIMALIA; EQUIDAE; RATTUS;

EID: 84855817737     PISSN: None     EISSN: 18750435     Source Type: Journal    
DOI: 10.2174/1875043501104010112     Document Type: Article

References (30)

1. Sharma P, Maffulli N. Biology of tendon injury: healing, modeling and remodeling. J Musculoskelet Neuronal Interact 2006; 6(2): 181-90.
2. Guest DJ, Smith MRW, Allen WR. Monitoring the fate of autologous and allogeneic mesenchymal progenitor cells injected into the superficial digital flexor tendon of horses: preliminary study. Equine Vet J 2008; 40(2): 178-81.
3. Vidal MA, Kilroy GE, Lopez MJ, et al. Characterization of equine adipose tissue-derived stromal cells: adipogenic and osteogenic capacity and comparison with bone marrow-derived mesenchymal stromal cells. Vet Surg 2007; 36(7): 613-22.
4. Koch TG, Heerkens T, Thomsen PD, et al. Isolation of mesenchymal stem cells from equine umbilical cord blood. BMC Biotechnol 2007; 7: 26.
5. Frisbie DD, Smith RKW. Clinical update on the use of mesenchymal stem cells in equine orthopaedics. Equine Vet J 2010; 42(1): 86-9.
6. Smith RKW. Mesenchymal stem cell therapy for equine tendinopathy. Disabil Rehabil 2008; 30(20): 1752.
7. Young RG, Butler DL, Weber W, et al. Use of mesenchymal stem cells in a collagen matrix for achilles tendon repair. J Orthop Res 1998; 16(4): 406-13.
8. Chong AKS, Ang AD, Goh JCH, et al. Bone marrow-derived mesenchymal stem cells influence early tendon-healing in a rabbit achilles tendon model. J Bone Joint Surg Am 2007; 89(1): 74-81.
9. Awad HA, Boivin GP, Dressler MR, et al. Repair of patellar tendon injuries using a cell-collagen composite. J Orthop Res 2003; 21(3): 420-31.
10. Hankemeier S, van Griensven M, Ezechieli M, et al. Tissue engineering of tendons and ligaments by human bone marrow stromal cells in a liquid fibrin matrix in immunodeficient rats: results of a histologic study. Arch Orthop Trauma Surg 2007; 127(9): 815-21.
11. Sarugaser R, Lickorish D, Baksh D, et al. Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 2005; 23(2): 220-9.
12. Schugar RC, Chirieleison SM, Wescoe KE, et al. High harvest yield, high expansion, and phenotype stability of CD146 mesenchymal stromal cells from whole primitive human umbilical cord tissue. J Biomed Biotechnol 2009; [Epub ahead (16)].
13. Farias VA, Linares-Fernández JL, Peñalver JL, et al. Human umbilical cord stromal stem cell express CD10 and exert contractile properties. Placenta 2011; 32(1): 86-95.
14. Sarugaser R, Hanoun L, Keating A, et al. Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy. PLoS ONE 2009; 4(8): e6498.
15. Dominici M, Blanc KL, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. Cytotherapy 2006; 8(4): 315-7.
16. Ennis J, Götherström C, Le Blanc K, et al. In vitro immunologic properties of human umbilical cord perivascular cells. Cytotherapy 2008; 10(2): 174-81.
17. Grinnemo KH, Månsson A, Dellgren G, et al. Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium. J Thorac Cardiovasc Surg 2004; 127(5): 1293-300.
18. Chen Y-J, Wang C-J, Yang KD, et al. Extracorporeal shock waves promote healing of collagenase-induced Achilles tendinitis and increase TGF-beta1 and IGF-I expression. J Orthopaed Res 2004; 22(4): 854-61.
19. Marsolais D, Cote CH, Frenette J. Pifithrin-alpha, an inhibitor of p53 transactivation, alters the inflammatory process and delays tendon healing following acute injury. Am J Physiol Regul Integr Comp Physiol 2007; 292(1): R321-7.
20. Williams IF, McCullagh KG, Goodship AE, Silver IA. Studies on the pathogenesis of equine tendonitis following collagenase injury. Res Vet Sci 1984; 36(3): 326-38.
21. Shi S, Key M, Kalra K. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 1991; 39(6): 741-8.
22. Emrani H. Umbilical cord perivascular cells: A mesenchymal cell source for treatment of tendon and ligament injuries. MSc thesis, University of Toronto, 2009.
23. Williams IF, Heaton A, McCullagh KG. Cell morphology and collagen types in equine tendon scar. Res Vet Sci 1980; 28(3): 302-10.
24. O'Brien M. Structure and metabolism of tendons. Scand J Med Sci Sports 1997; 7(2): 55-61.
25. Davies JE, Matta R, Mendes VC, et al. Development, characterization and clinical use of a biodegradable composite scaffold for bone engineering in oro-maxillo-facial surgery. Organogenesis 2010; 6(3): 161-6.
26. Zebardast N, Lickorish D, Davies JE. Human umbilical cord perivascular cells (HUCPVC): A mesenchymal cell source for dermal wound healing. Organogenesis 2010; 6(4): 197-203.
27. Sharma P. Tendon Injury and Tendinopathy: Healing and Repair. J Bone Joint Surg Am 2005; 87: 187-202.
28. Hankemeier S, Hurschler C, Zeichen J, et al. Bone marrow stromal cells in a liquid fibrin matrix improve the healing process of patellar tendon window defects. Tissue Eng Part A 2009; 15(5): 1019-30.
29. Oshiro W, Lou J, Xing X, et al. Flexor tendon healing in the rat: a histologic and gene expression study. J Hand Surg 2003; 28(5): 814-23.
30. Richardson LE, Dudhia J, Clegg PD, et al. Stem cells in veterinary medicine-attempt at regenerating equine tendon after injury. Trends Biotechnol 2007; 25(9): 409-16.