An experimental design approach for the forced degradation studies and development of a stabilityindicating lc method for eplerenone in tablets

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 17, 2011, Pages 2020-2031

  Sonawane, Sandeep ^a   Gide, Paraag ^a  

^a MET's Institute of Pharmacy   (India)

Author keywords

Eplerenone; Experimental design; LC MS; Multiple regression; Stabilityindicating method

Indexed keywords

ACCURACY AND PRECISION; ACTIVE PHARMACEUTICAL INGREDIENTS; CHROMATOGRAPHIC METHODS; DEGRADATION PRODUCTS; EPLERENONE; FORCED DEGRADATION; LC-MS; MASS FRAGMENTATION; MOBILE PHASE; MULTIPLE REGRESSIONS; PHOTOLYTIC CONDITIONS; QUANTITATIVE DETERMINATIONS; STABILITYINDICATING METHOD; TRIAL AND ERROR;

CHROMATOGRAPHIC ANALYSIS; DEGRADATION; DESIGN; DRUG PRODUCTS; HYDROGEN; HYDROGEN PEROXIDE; LIQUID CHROMATOGRAPHY; METHANOL; STATISTICS;

DESIGN OF EXPERIMENTS;

EPLERENONE;

ARTICLE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG OXIDATION; DRUG SOLUTION; DRUG STABILITY; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTOLYSIS; TABLET FORMULATION; TEMPERATURE STRESS; VALIDATION STUDY;

EID: 84855803163     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.582913     Document Type: Article

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