The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4

Biochemical and Biophysical Research Communications

Volumn 417, Issue 1, 2012, Pages 346-351

  Vatsyayan, Rit ^a   Lelsani, Poorna Chandra Rao ^a   Chaudhary, Pankaj ^a   Kumar, Sushil ^a   Awasthi, Sanjay ^a   Awasthi, Yogesh C ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

4 Hydroxy t 2 nonenal; Glutathione S transferasesA4 4; Lipid peroxidation; Retinal pigment epithelium cells; Vascular endothelial growth factor; Vascular endothelial growth factor receptor

Indexed keywords

4 HYDROXYNONENAL; GLUTATHIONE TRANSFERASE A4; MATRIGEL; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL CULTURE; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DOSE RESPONSE; FETUS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MALE; OXIDATIVE STRESS; PARACRINE SIGNALING; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WOUND HEALING;

ALDEHYDES; CELL LINE; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; GLUTATHIONE TRANSFERASE; HORMESIS; HUMANS; MALE; OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84855790697     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.113     Document Type: Article

References (28)

1. Chung F.L., Chen H.J., Nath R.G. Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis 1996, 17:2105-2111.
2. K. Uchida, E.R. Stadtman, Modification of histidine residues in proteins by reaction with 4-hydroxynonenal, Proc. Natl.Acad. Sci. USA 89 (1992) 4544-4548.
3. Singh S.P., Niemczyk M., Saini D., et al. Disruption of the mGsta4 gene increases life span of C57BL mice. J. Gerontol. A Biol. Sci. Med. Sci. 2010, 65:14-23.
4. Yancopoulos G.D., Davis S., Gale N.W., et al. Vascular-specific growth factors and blood vessel formation. Nature 2000, 407:242-248.
5. Adamis A.P., Shima D.T., Yeo K.T., et al. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 1993, 193:631-638.
6. Vatsyayan R., Chaudhary P., Sharma A., et al. Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells. Exp. Eye Res. 2011, 92:147-154.
7. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
9. Xu K.P., Yu F.S. Cross talk between c-Met and epidermal growth factor receptor during retinal pigment epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 2007, 48:2242-2248.
10. Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 1991, 11:81-128.
11. Awasthi Y.C., Yang Y., Tiwari N.K., et al. Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases. Free Radic. Biol. Med. 2004, 37:607-619.
12. Awasthi Y.C., Sharma R., Sharma A., et al. Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death. Free Radic. Biol. Med. 2008, 45:111-118.
13. Li J., Sharma R., Patrick B., et al. Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal. Biochemistry 2006, 45:12253-12264.
14. P.Chaudhary, R. Sharma, A. Sharma, et al., Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling, Biochemistry 49 (2010) 6263-6275.
15. Sharma A., Sharma R., Chaudhary P., et al. 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells. Arch. Biochem. Biophys. 2008, 480:85-94.
16. Bressler N.M., Bressler S.B., Fine S.L. Age-related macular degeneration. Surv. Ophthalmol. 1988, 32:375-413.
17. Liang C.C., Park A.Y., Guan J.L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat. Protoc. 2007, 2:329-333.
18. Ohno-Matsui, I. Morita, J. Tombran-Tink, et al., Novel mechanism for age-related macular degeneration:an equilibrium shift between the angiogenesis factors VEGF and PEDF, J. Cell Physiol. 189 (2001) 323-333.
19. Liekens S., De Clercq E., Neyts J. Angiogenesis: regulators and clinical applications. Biochem. Pharmacol. 2001, 61:253-270.
20. Papetti M., Herman I.M. Mechanisms of normal and tumor-derived angiogenesis. Am. J. Physiol. Cell Physiol. 2002, 282:C947-C970.
21. Kohn E.C., Alessandro R., Spoonster J. Et al., Angiogenesis: role of calcium-mediated signal transduction. Proc. Natl. Acad. Sci. USA 1995, 92:1307-1311.
22. Liu W., Akhand A.A., Kato M., et al. 4-Hydroxynonenal Triggers an Epidermal Growth Factor Receptor-Linked Signal Pathway for Growth Inhibition. J. Cell Sci. 1999, 112:2409-2417.
23. Yang Y., Sharma A., Sharma R., et al. Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA induced apoptosis: role of 4-hydroxynonenal in UVA mediated signaling for apoptosis. J. Biol. Chem. 2003, 278:41380-41388.
24. Cheng J.Z., Sharma R., Yang Y., et al. Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress. J. Biol. Chem. 2001, 276:41213-41223.
25. Jacobs A.T., Marnett L.J. Heat shock factor 1 attenuates 4-Hydroxynonenal mediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL. J. Biol. Chem. 2007, 282:33412-33420.
26. T. Ishii., K. Itoh, E. Ruiz, et al., Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal, Circ. Res. 94 (2004) 609-616.
27. Khelifi A.F., D'Alcontres M.S., Salomoni P. Daxx is required for stress-induced cell death and JNK activation. Cell Death Differ. 2005, 12:724-733.
28. Lotem J., Peled-Kamar M., Groner Y., et al. Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines. Proc. Natl. Acad. Sci. USA 1996, 93:9166-9171.