Thyroid hormones in children on antiepileptic therapy

International Journal of Neuroscience

Volumn 122, Issue 2, 2012, Pages 69-73

  Aygün, Fatih ^a   Ekici, Bariş ^a   Aydinli, Nur ^a   Aydin, Banu Küçükemre ^a   Baş, Firdevs ^a   Tatli, Burak ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

electroencephalography; epilepsy; thyroid hormones; thyroid stimulating hormone; valproate

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETIRACETAM; OXCARBAZEPINE; PHENOBARBITAL; THYROTROPIN; THYROXINE; TOPIRAMATE; VALPROIC ACID;

ADOLESCENT; ANTICONVULSANT THERAPY; ARTICLE; BENIGN CHILDHOOD EPILEPSY; CHILD; ELECTROENCEPHALOGRAPHY; FEMALE; FOLLOW UP; FREE THYROXINE INDEX; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD; SIDE EFFECT; THYROID DISEASE; THYROID FUNCTION; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; IRAN; MALE; RETROSPECTIVE STUDIES; THYROID DISEASES; THYROID FUNCTION TESTS; THYROTROPIN; THYROXINE;

EID: 84855774306     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2011.627486     Document Type: Article

References (17)

1. Luef G, Rauchenzauner M. Epilepsy and hormones: a critical review. Epilepsy Behav. 2009;15:73-7.
2. Cansu A. Antiepileptic drugs and hormones in children. Epilepsy Res. 2010;89:89-95.
3. Pennell PB. Hormonal aspects of epilepsy. Neurol Clin. 2009;27:941-65.
4. Setian NS. Hypothyroidism in children: diagnosis and treatment. J Pediatr. (Rio J) 2007;83:209-16.
5. Benedetti MS, Whomsley R, Baltes E, Tonner F. Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction. Eur J Clin Pharmacol. 2005;61:863-72. (Pubitemid 41803695)
6. Oppenheimer JH, McPherson HT. The syndrome of iodideinduced goiter and myxedema. Am J Med. 1961;30:281-8.
7. Cansu A, Serdaroglu A, Camurdan O, Hirfanoglu T, Bideci A, Gucuyener K. The evaluation of thyroid functions, thyroid antibodies, and thyroid volumes in children with epilepsy during short-term administration of oxcarbazepine and valproate. Epilepsia. 2006;47:1855-9. (Pubitemid 44730054)
8. Hirfanoglu T, Serdaroglu A, Camurdan O, Cansu A, Bideci A, Cinaz P, Gucuyener K. Thyroid function and volume in epileptic children using carbamazepine, oxcarbazepine and valproate. Pediatr Int. 2007;49:822-6. (Pubitemid 350197123)
9. Attilakos A, Katsarou E, Prassouli A, Mastroyianni S, Voudris K, Fotinou A, Garoufi A. Thyroid function in children with epilepsy treated with sodium valproatemonotherapy: a prospective study. Clin Neuropharmacol. 2009;32:32-4.
10. de Vries L, Karasik A, Landau Z, Phillip M, Kiviti S, Goldberg- Stern H. Endocrine effects of valproate in adolescent girls with epilepsy. Epilepsia. 2007;48:470-77. (Pubitemid 46365184)
11. Verrotti A, Basciani F, Morresi S,Morgese G, Chiarelli F. Thyroid hormones in epileptic children receiving carbamazepine and valproic acid. Pediatr Neurol. 2001;25:43-6. (Pubitemid 32727774)
12. Castro-Gago M, Novo-Rodríguez MI, Gómez-Lado C, Rodríguez-García J, Rodríguez-Segade S, Eirís-Puñal J. Evolution of subclinical hypothyroidism in children treated with antiepileptic drugs. Pediatr Neurol. 2007;37:426-30. (Pubitemid 350087635)
13. Vainionpää LK, Mikkonen K, Rättyä J, Knip M, Pakarinen AJ, Myllylä VV, Isojärvi JIT. Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication. Epilepsia. 2004;45:197-203. (Pubitemid 38332744)
14. Löscher W, Schmidt D. Increase of human plasma GABA by sodium valproate. Epilepsia. 1980;21:611-5. (Pubitemid 11179700)
15. Graf WD, Oleinik OE, Glauser TA,Maertens P, Eder DN, Pippenger CE. Altered antioxidant enzyme activities in children with a serious adverse experience related to valproic acid therapy. Neuropediatrics. 1998;29:195-201. (Pubitemid 28396070)
16. Tanaka K, Kodoma S, Yokohama S, Komatsu M, Konishi H, Momota K, Matsuo T. Thyroid function in children with long term anticonvulsant treatment. Pediatr Neurol. 1987;13: 90-4. (Pubitemid 17167675)
17. Yesiltepe Mutlu G R, Vitrinel A, Agzikuru T, Cömert S, Edag GÇ , Akin Y. Serum hormone levels of children receiving anticonvulsants. Ege J Med. 2008;47:47-50.