Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28)

Virology Journal

Volumn 9, Issue , 2012, Pages

  Tomtishen Iii, John ^a  

^a BUCKNELL UNIVERSITY   (United States)

Author keywords

Confocal microscopy; HCMV; Human cytomegalovirus; pp150; pp28; pp65; pp71; Tegument; Transfection

Indexed keywords

CYTOMEGALOVIRUS ANTIGEN PP65; CYTOMEGALOVIRUS PROTEIN PP150; CYTOMEGALOVIRUS PROTEIN PP28; CYTOMEGALOVIRUS PROTEIN PP71; PLASMID DNA; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRULENCE FACTOR;

CYTOMEGALOVIRUS INFECTION; GENE EXPRESSION; HUMAN CYTOMEGALOVIRUS; LIFE CYCLE; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; VIRION; VIRUS CAPSID; VIRUS ENTRY; VIRUS MORPHOLOGY; VIRUS PARTICLE; CYTOMEGALOVIRUS; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNE EVASION; METABOLISM; PATHOGENICITY; PHYSIOLOGY; VIRUS ASSEMBLY; VIRUS RELEASE;

BETAHERPESVIRINAE; HERPESVIRIDAE; HUMAN HERPESVIRUS 5;

CYTOMEGALOVIRUS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; IMMUNE EVASION; VIRAL STRUCTURAL PROTEINS; VIRULENCE FACTORS; VIRUS ASSEMBLY; VIRUS RELEASE;

EID: 84855767648     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-9-22     Document Type: Review

References (46)

1. Cytomegaloviruses. Mocarski ES, Shenk T, Pass RF, Fields virology Philadelphia, PA: Lippincott Williams & Wilkins, Knipe DM, Howley PM, 5 2007 2701 2772
2. A DNA-based vaccine for the prevention of human cytomegalovirus- associated diseases. Selinsky C, Luke C, Wloch M, Geall A, Hermanson G, et al. Human Vaccines 2005 1 16 23 17038834
3. Fibroblasts, epithelial cells, endothelial cells, and smooth muscle cells are major targets of human cytomegalovirus infection in lung and gastrointestinal tissues. Sinzger C, Grefte A, Plachter B, Gouw ASH, The TH, Jahn G, J Gen Virol 1995 76 741 750 10.1099/0022-1317-76-4-741 9049319
4. Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer? Soderberg-Naucler C, J Intern Med 2006 259 219 246 10.1111/j.1365-2796.2006.01618.x 16476101
5. Clinical relevance of cytomegalovirus infection in patients with disorders of the immune system. Steininger C, Clin Microbiol Infect 2007 13 953 963 10.1111/j.1469-0691.2007.01781.x 17803749 (Pubitemid 47382250)
6. Congenital cytomegalovirus (CMV) infection as a cause of permanent bilateral hearing loss: a quantitative assessment. Grosse SD, Ross DS, Dollard SC, J Clin Virol 2008 41 57 62 10.1016/j.jcv.2007.09.004 17959414 (Pubitemid 351179445)
7. Human cytomegalovirus infection and T cell immunosenescence: a mini review. Koch S, Solana R, Dela Rosa O, Pawelec G, Mech Ageing Dev 2006 127 538 543 10.1016/j.mad.2006.01.011 16513159
8. + cells. Saffert RT, Penkert RR, Kalejta RF, J Virol 2010 84 5594 5604 10.1128/JVI.00348-10 20335255
9. Cytomegaloviruses. Mocarski ES, Shenk T, Pass RF, Fields Virology Philadelphia, PA: Lippincott Williams & Wilkins, Knipe DM, Howley PM, 5 2007 2701 2772
10. Antiviral drugs for cytomegalovirus disease. Biron KK, Antivir Res 2006 71 154 163 10.1016/j.antiviral.2006.05.002 16765457 (Pubitemid 44223768)
11. Human Cytomegalovirus. Shenk Thomas, Stinski Mark F, Current Topics in Microbiology and Immunology Berlin: Springer 1 2008 325 Print
12. Tegument proteins of human cytomegalovirus. Kalejta RF, Microbiol Mol Biol Rev 2008 72 249 265 10.1128/MMBR.00040-07 18535146 (Pubitemid 351822292)
13. Latency and reactivation of human cytomegalovirus. Sinclair J, Sissons P, J Gen Virol 2006 87 1763 1779 10.1099/vir.0.81891-0 16760381 (Pubitemid 43985862)
14. Isolation and characterization of a noninfectious virion-like particle released from cells infected with human strains of cytomegalovirus. Irmiere A, Gibson W, Virology 1983 130 118 133 10.1016/0042-6822(83)90122-8 6314643 (Pubitemid 14226847)
15. Three-dimensional visualization of tegument/capsid interactions in the intact human cytomegalovirus. Chen DH, Jiang H, Lee M, Liu F, Zhou ZH, Virology 1999 260 10 16 10.1006/viro.1999.9791 10405351 (Pubitemid 29391728)
16. Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. Varnum SM, Streblow DN, Monroe ME, Smith P, Auberry KJ, Pasa-Tolic L, Wang D, Camp DG, Rodland K, Wiley S, Britt W, Shenk T, Smith RD, Nelson J, J Virol 2004 78 10960 10966 10.1128/JVI.78.20.10960-10966.2004 15452216 (Pubitemid 39299636)
17. Functions of human cytomegalovirus tegument proteins prior to immediate early gene expression. Kalejta RF, Curr Top Microbiol Immunol 2008 325 101 116 10.1007/978-3-540-77349-8-6 18637502
18. Major tegument protein pp 65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages. Chevillotte M, Landwehr S, Linta L, Frascaroli G, Lüske A, et al. J Virol 2009 83 2480 2490 10.1128/JVI.01818-08 19116255
19. Identification of the major late human cytomegalovirus matrix protein pp 65 as a target antigen for CD8 virus-specific cytotoxic T lymphocytes. McLaughlin-Taylor E, Pande H, Forman SJ, Tanamachi B, Li CR, Zaia JA, Greenberg PD, Riddell SR, J Med Virol 1994 43 103 110 10.1002/jmv.1890430119 8083644 (Pubitemid 24146353)
20. Human cytomegalovirus protein pp 65 mediates accumulation of HLA-DR in lysosomes and destruction of the HLA-DR alpha-chain. Odeberg J, Plachter B, Branden L, Soderberg-Naucler C, Blood 2003 101 4870 4877 10.1182/blood-2002-05- 1504 12609847 (Pubitemid 36868942)
21. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Gilbert MJ, Riddell SR, Plachter B, Greenberg PD, Nature 1996 383 720 722 10.1038/383720a0 8878482 (Pubitemid 26360648)
22. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Gilbert MJ, Riddell SR, Plachter B, Greenberg PD, Nature 1996 383 720 722 10.1038/383720a0 8878482 (Pubitemid 26360648)
23. Inhibition of the NKp30 activating receptor by pp 65 of human cytomegalovirus. Arnon TI, Achdout H, Levi O, Markel G, Saleh N, Katz G, Gazit R, Gonen-Gross T, Hanna J, Nahari E, Porgador A, Honigman A, Plachter B, Mevorach D, Wolf DG, Mandelboim O, Nat Immunol 2005 6 515 523 15821739 (Pubitemid 41716765)
24. Tumor and viral recognition by natural killer cells receptors. Arnon TI, Markel G, Mandelboim O, Semin Cancer Biol 2006 16 348 358 10.1016/j.semcancer. 2006.07.005 16893656 (Pubitemid 44311503)
25. Major human cytomegalovirus structural protein pp 65 (ppUL83) prevents interferon response factor 3 activation in the interferon response. Abate DA, Watanabe S, Mocarski E, J Virol 2004 78 10995 11006 10.1128/JVI.78.20.10995- 11006.2004 15452220 (Pubitemid 39299640)
26. Regulation of cytomegalovirus gene expression: and promoters are trans activated by viral functions in permissive human fibroblasts. Spaete RR, Mocarski ES, J Virol 1985 56 135 143 2993644 (Pubitemid 16256865)
27. Daxx: death or survival protein? Salomoni P, Khelifi AF, Trends Cell Biol 2006 16 97 104 10.1016/j.tcb.2005.12.002 16406523 (Pubitemid 43247405)
28. Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp 71 protein stimulates viral immediate early gene expression. Saffert RT, Kalejta RF, J Virol 2006 80 3863 3871 10.1128/JVI.80.8.3863-3871.2006 16571803
29. Human cytomegalovirus tegument protein pp 71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle. Baldick CJ, Marchini A, Patterson CE, Shenk T, J Virol 1997 71 4400 4408 9151830 (Pubitemid 27204129)
30. Human cytomegalovirus protein pp 71 disrupts major histocompatibility complex class I cell surface expression. Trgovcich J, Cebulla C, Zimmerman P, Sedmak DD, J Virol 2006 80 951 63 10.1128/JVI.80.2.951-963.2006 16378997 (Pubitemid 43062907)
31. Control of cytoplasmic maturation events by cytomegalovirus tegument protein pp 150. Tandon R, Mocarski ES, J Virol 2008 82 9433 9444 10.1128/JVI.00533-08 18653449
32. Cytoplasmic envelopment of human cytomegalovirus requires a postlocalization function of a tegument protein pp 28 within the assembly compartment. Seo JY, Britt WJ, J Virol 2007 81 6536 6547 10.1128/JVI.02852-06 17392372 (Pubitemid 46878058)
33. Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface. Compton T, Nepomuceno RR, Nowlin DM, Virology 1992 191 387 395 10.1016/0042-6822(92)90200-9 1329327
34. Cell-cycle-dependent localization of human cytomegalovirus UL83 phosphoprotein in the nucleolus and modulation of viral gene expression in human embryo fibroblasts in vitro. Arcangeletti M-C, Rodighiero I, Mirandola P, De Conto F, Covan S, Germini D, Razin S, Dettori G, Chezzi C, J Cell Biochem 2011 112 307 317 10.1002/jcb.22928 21053310
35. Accumulation of virion tegument and envelope proteins in a stable cytoplasmic compartment during human cytomegalovirus replication: characterization of a potential site of virus assembly. Sanchez V, Greis KD, Sztul E, Britt WJ, J Virol 2000 74 975 986 10.1128/JVI.74.2.975-986.2000 10623760 (Pubitemid 30036234)
36. Nuclear export of the human cytomegalovirus tegument protein pp 65 requires cyclin-dependent kinase activity and the Crm1 exporter. Sanchez V, Mahr JA, Orazio NI, Spector DH, J Virol 2007 81 11730 11736 10.1128/JVI.02760-06 17715235 (Pubitemid 47623805)
37. Cellular and viral control over the initial events of human cytomegalovirus experimental latency in CD34+ cells. Saffert RT, Penkert RR, Kalejta RF, J Virol 2010 84 5594 5604 10.1128/JVI.00348-10 20335255
38. Intracellular localization and expression of the human cytomegalovirus matrix phosphoprotein pp 71 (UL82): evidence for its translocation into the nucleus. Hensel GM, Meyer HH, Buchmann I, Pomnmerehne D, Schmolke S, Plachter B, Radsak K, Kern HF, J Gen Virol 1996 77 3087 3097 10.1099/0022-1317-77-12-3087 9000101 (Pubitemid 27056529)
39. Nuclear localization of the human cytomegalovirus tegument protein pp 150 (ppUL32). Hensel G, Meyer H, Gartner S, Brand G, Kern HF, J Gen Virol 1995 76 1591 1601 10.1099/0022-1317-76-7-1591 9049366
40. Betaherpesvirus-conserved cytomegalovirus tegument protein ppUL32 (pp 150) controls cytoplasmic events during virion maturation. AuCoin DP, Smith GB, Meiering CD, Mocarski ES, J Virol 2006 80 8199 8210 10.1128/JVI.00457-06 16873276 (Pubitemid 44182320)
41. Human cytomegalovirus pp 28 (UL99) localizes to a cytoplasmic compartment which overlaps the endoplasmic reticulum-Golgi-intermediate compartment. Sanchez V, Sztul E, Britt WJ, J Virol 2000 74 3842 3851 10.1128/JVI.74.8.3842- 3851.2000 10729158 (Pubitemid 30180326)
42. Advances in fluorescent protein technology. Shaner NC, Patterson GH, Davidson MW, J Cell Sci 2007 120 4247 4260 10.1242/jcs.005801 18057027
43. Green fluorescent protein as a marker for gene expression. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC, Science 1994 263 802 805 10.1126/science.8303295 8303295 (Pubitemid 24093206)
44. The green fluorescent protein. Tsien RY, Annu Rev Biochem 1998 67 509 544 10.1146/annurev.biochem.67.1.509 9759496 (Pubitemid 28411137)
45. Tomtishen John Paul, Tegument Protein Subcellular Localization of Human Cytomegalovirus Bucknell University, Lewisburg 2011 BS with Honors Thesis. Print
46. Nuclear targeting of the tegument protein pp 65 (UL83) of human cytomegalovirus: an unusual bipartite nuclear localization signal functions with other portions of the protein to mediate its efficient nuclear transport. Schmolke S, Drescher P, Jahn G, Plachter B, J Virol 1995 69 1071 1078 7815485