De novo deletions and duplications detected by array CGH: A study of parental origin in relation to mechanisms of formation and size of imbalance

European Journal of Human Genetics

Volumn 20, Issue 2, 2012, Pages 155-160

  Sibbons, Charlene ^a,b   Morris, Joan K ^c   Crolla, John A ^a,b   Jacobs, Patricia A ^a,b   Thomas, N Simon ^a,b  

^a SALISBURY DISTRICT HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

array CGH; de novo chromosome abnormality; deletions and duplications; low copy repeats; non allelic homologous recombination; parental and chromosomal origin

Indexed keywords

ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME REARRANGEMENT; COMPARATIVE GENOMIC HYBRIDIZATION; COMPARATIVE STUDY; DE NOVO CHROMOSOME ABNORMALITY; FEMALE; GENE DELETION; GENE DUPLICATION; HOMOLOGOUS RECOMBINATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NONALLELIC HOMOLOGOUS RECOMBINATION; PARENTAGE ANALYSIS; PARENTAL AGE; PRIORITY JOURNAL; SEGMENTAL DUPLICATION;

AGE FACTORS; ALLELIC IMBALANCE; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GENE DUPLICATION; HUMANS; MALE; SEGMENTAL DUPLICATIONS, GENOMIC; SEQUENCE DELETION; TRANSLOCATION, GENETIC;

EID: 84855767077     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2011.182     Document Type: Article

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